Cochrane · systematic review · CD009221
Pharmacotherapy for chronic cognitive impairment in traumatic brain injury
Dougall, D, Poole, N, Agrawal, N · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Dementia and Cognitive ImprovementAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 20%Very low 3 · 60%Low 1 · 20%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Pharmacological agents compared to placebo for chronic cognitive impairment in traumatic brain injury
Population: Participants with chronic cognitive impairment in traumatic brain injury
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Cognitive performance on psychometric tests Pharmacological agents vs placebo | no estimate extracted | 4 studies · 274 participants | Very low Downgraded: indirectness |
Clinical global improvement Pharmacological agents vs placebo | no estimate extracted | 1 study · 51 participants | Low Downgraded: indirectness |
Acceptability Pharmacological agents vs placebo | no estimate extracted | 4 studies · 274 participants | Very low Downgraded: indirectness |
Safety Pharmacological agents vs placebo | no estimate extracted | 4 studies · 274 participants | Very low Downgraded: indirectness |
Mortality Pharmacological agents vs placebo | no estimate extracted | 4 studies · 274 participants | Ungraded |