Cochrane Review Group

Pregnancy and Childbirth

252 systematic reviews in Pregnancy and Childbirth ask 3,601 questions. 20.2% have no studies to answer them, 23% rest on very low certainty evidence and 17.6% reach moderate or high certainty.

Reviews

252

Questions

3,601

current versions

No studies

20.2%

Moderate or high

17.6%

No studies 726 · 20.2%Ungraded 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Pregnancy and Childbirth

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Magnesium sulphate vs placebo (outcomes Major neurodevelopmental disability (school age)** · women at risk of preterm birth (< 34 weeks' gestation) Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus (2024) · Cochrane	RR 0.92 [0.53, 1.62]	2 studies · 940 participants	Very low
Magnesium sulphate vs placebo (outcomes Breastfeeding at hospital discharge** · women at risk of preterm birth (< 34 weeks' gestation) Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus (2024) · Cochrane	no estimate extracted	NR	No studies
Magnesium sulphate vs placebo (outcomes Women’s views of treatment** · women at risk of preterm birth (< 34 weeks' gestation) Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Midwife continuity models vs other models of care Third or fourth degree tear · childbearing women and their infants (all) (important/secondary outcomes) Midwife continuity of care models versus other models of care for childbearing women (2024) · Cochrane	RR 1.1 [0.81, 1.49]	7 studies · 9437 participants	Very low
Summary of findings table ‐ Midwife continuity models vs other models of care Maternal readmission within 28 days · childbearing women and their infants (all) (important/secondary outcomes) Midwife continuity of care models versus other models of care for childbearing women (2024) · Cochrane	RR 1.52 [0.78, 2.96]	1 study · 1195 participants	Very low
Summary of findings table ‐ Midwife continuity models vs other models of care Attendance at birth by known midwife · childbearing women and their infants (all) (important/secondary outcomes) Midwife continuity of care models versus other models of care for childbearing women (2024) · Cochrane	RR 9.13 [5.87, 14.21]	11 studies · 9273 participants	Very low
Summary of findings table ‐ Midwife continuity models vs other models of care Apgar score less than or equal to 7 at 5 minutes · childbearing women and their infants (all) (important/secondary outcomes) Midwife continuity of care models versus other models of care for childbearing women (2024) · Cochrane	RR 0.95 [0.72, 1.24]	13 studies · 12806 participants	Very low
Summary of findings table ‐ Midwife continuity models vs other models of care Fetal loss before 24 weeks gestation · childbearing women and their infants (all) (important/secondary outcomes) Midwife continuity of care models versus other models of care for childbearing women (2024) · Cochrane	RR 0.82 [0.67, 1.01]	12 studies · 15913 participants	Very low
Summary of findings table ‐ Midwife continuity of care models vs other models of care Regional analgesia (epidural/spinal) · childbearing women and their infants (all) (critical outcomes) Midwife continuity of care models versus other models of care for childbearing women (2024) · Cochrane	RR 0.85 [0.79, 0.92]	15 studies · 17754 participants	Very low
Summary of findings table ‐ Midwife continuity of care models vs other models of care Fetal loss at or after 24 weeks gestation · childbearing women and their infants (all) (critical outcomes) Midwife continuity of care models versus other models of care for childbearing women (2024) · Cochrane	RR 1.24 [0.73, 2.13]	12 studies · 16122 participants	Very low
Summary of findings table ‐ Midwife continuity of care models vs other models of care Neonatal death (baby born alive at any gestation and dies within 28 days) · childbearing women and their infants (all) (critical outcomes) Midwife continuity of care models versus other models of care for childbearing women (2024) · Cochrane	RR 0.85 [0.43, 1.71]	10 studies · 14718 participants	Very low
Summary of findings table ‐ Vitamin B12 supplementation vs placebo/no vitamin B12 supplementation Maternal anaemia · pregnant women Vitamin B12 supplementation during pregnancy for maternal and child health outcomes (2024) · Cochrane	RR 1.08 [0.93, 1.26]	2 studies · 284 participants	Very low

Reviews 252

Different strategies for diagnosing gestational diabetes to improve maternal and infant health

Farrar, D, Duley, L, et al. · Cochrane Database of Systematic Reviews · 2017

Pregnancy and Childbirth

Thinnest evidence

Reviews 252

Different strategies for diagnosing gestational diabetes to improve maternal and infant health

Screening for gestational diabetes mellitus based on different risk profiles and settings for improving maternal and infant health

Medical treatments for incomplete miscarriage

Fetal and umbilical Doppler ultrasound in high‐risk pregnancies

Pharmacological and mechanical interventions for labour induction in outpatient settings

Oral anti‐diabetic agents for women with established diabetes/impaired glucose tolerance or previous gestational diabetes planning pregnancy, or pregnant women with pre‐existing diabetes

Preconception care for diabetic women for improving maternal and infant health

Intermittent auscultation (IA) of fetal heart rate in labour for fetal well‐being

Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy

Pushing/bearing down methods for the second stage of labour

Planned early delivery versus expectant management for hypertensive disorders from 34 weeks gestation to term

Different types of dietary advice for women with gestational diabetes mellitus

Methods of term labour induction for women with a previous caesarean section

Combined diet and exercise interventions for preventing gestational diabetes mellitus

Interventions for treating genital Chlamydia trachomatis infection in pregnancy

Different methods and settings for glucose monitoring for gestational diabetes during pregnancy

Regimens of ultrasound surveillance for twin pregnancies for improving outcomes

Assessment and support during early labour for improving birth outcomes

Iodine supplementation for women during the preconception, pregnancy and postpartum period

Different insulin types and regimens for pregnant women with pre‐existing diabetes

Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes

Lifestyle interventions for the treatment of women with gestational diabetes

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour

Bed rest with and without hospitalisation in multiple pregnancy for improving perinatal outcomes

Insulin for the treatment of women with gestational diabetes