Cochrane · systematic review · CD011970

Lifestyle interventions for the treatment of women with gestational diabetes

Brown, J, Alwan, NA, West, J, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
18
current version
GRADE rated
13
No studies
5
Included studies
NR
No studies 5 · 27.8%Ungraded 0 · 0%Very low 1 · 5.6%Low 7 · 38.9%Moderate 4 · 22.2%High 1 · 5.6%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Lifestyle interventions versus control ‐ Maternal outcomes

Population: Women with gestational diabetes
7 questions
OutcomeEffectEvidenceStatus / GRADE
Hypertensive disorders of pregnancy (pre‐eclampsia)
Lifestyle interventions vs control ‐ Maternal outcomes
RR 0.7 [0.4, 1.22]4 studies · 2796 participantsLow
Downgraded: inconsistency
Perineal trauma/tear
Lifestyle interventions vs control ‐ Maternal outcomes
RR 1.04 [0.93, 1.18]1 study · 1000 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Caesarean section
Lifestyle interventions vs control ‐ Maternal outcomes
RR 0.9 [0.78, 1.05]10 studies · 3545 participantsLow
Induction of labour
Lifestyle interventions vs control ‐ Maternal outcomes
RR 1.2 [0.99, 1.46]4 studies · 2699 participantsHigh
Postnatal depression
Lifestyle interventions vs control ‐ Maternal outcomes
RR 0.49 [0.31, 0.78]1 study · 573 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Postnatal weight retention or return to pre‐pregnancy weight
Lifestyle interventions vs control ‐ Maternal outcomes
RR 1.75 [1.05, 2.9]1 study · 156 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Development of type 2 diabetes (
Lifestyle interventions vs control ‐ Maternal outcomes
RR 0.98 [0.54, 1.76]2 studies · 486 participantsLow
Downgraded: risk of bias, imprecision, inconsistency

Lifestyle versus control ‐ Neonatal and later outcomes

Population: Women with gestational diabetes
11 questions
OutcomeEffectEvidenceStatus / GRADE
Large‐for‐gestational age
Lifestyle vs control ‐ Neonatal and later outcomes
RR 0.6 [0.5, 0.71]6 studies · 2994 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Perinatal (fetal and neonatal death) and later infant mortality
Lifestyle vs control ‐ Neonatal and later outcomes
RR 0.09 [0.01, 1.7]2 studies · 1988 participantsLow
Composite outcome in infant (death, shoulder dystocia, nerve palsy, bone fracture)
Lifestyle vs control ‐ Neonatal and later outcomes
RR 0.57 [0.21, 1.55]2 studies · 1930 participantsVery low
Downgraded: inconsistency
Neonatal hypoglycaemia
Lifestyle vs control ‐ Neonatal and later outcomes
RR 0.99 [0.65, 1.52]6 studies · 3000 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Adiposity (neonatal) ‐ Neonatal fat mass (g)
Lifestyle vs control ‐ Neonatal and later outcomes
no estimate extracted1 study · 958 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Adiposity (child) ‐ Childhood BMI > 85th percentile
Lifestyle vs control ‐ Neonatal and later outcomes
RR 0.91 [0.75, 1.11]3 studies · 767 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Adiposity (adult) not measured
Lifestyle vs control ‐ Neonatal and later outcomes
no estimate extractedNRNo studies
Diabetes (type 2) (child) ‐ not measured
Lifestyle vs control ‐ Neonatal and later outcomes
no estimate extractedNRNo studies
Diabetes (type 2) (adult) ‐ not measured
Lifestyle vs control ‐ Neonatal and later outcomes
no estimate extractedNRNo studies
Neurosensory disability (child) ‐ not measured
Lifestyle vs control ‐ Neonatal and later outcomes
no estimate extractedNRNo studies
Neurosensory disability (adult) ‐ not measured
Lifestyle vs control ‐ Neonatal and later outcomes
no estimate extractedNRNo studies