Cochrane · systematic review · CD008991

Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy

Alfirevic, Z, Stampalija, T, Medley, N · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 50%Moderate 2 · 33.3%High 1 · 16.7%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Cerclage versus no cerclage

Population: preventing preterm birth in women with singleton pregnancy
6 questions
OutcomeEffectEvidenceStatus / GRADE
All perinatal losses
Cerclage vs no cerclage
RR 0.82 [0.65, 1.04]10 studies · 2927 participantsModerate
Downgraded: imprecision
Serious neonatal morbidity
Cerclage vs no cerclage
RR 0.8 [0.55, 1.18]6 studies · 883 participantsLow
Downgraded: imprecision
Baby discharged home healthy
Cerclage vs no cerclage
RR 1.02 [0.97, 1.06]4 studies · 657 participantsModerate
Downgraded: imprecision
Stillbirths
Cerclage vs no cerclage
RR 0.89 [0.45, 1.75]5 studies · 1803 participantsLow
Downgraded: imprecision
Neonatal deaths before discharge
Cerclage vs no cerclage
RR 0.85 [0.53, 1.39]6 studies · 1714 participantsLow
Downgraded: imprecision
Preterm birth before 34 completed weeks
Cerclage vs no cerclage
RR 0.77 [0.66, 0.89]9 studies · 2415 participantsHigh