Cochrane · systematic review · CD012031
Bed rest with and without hospitalisation in multiple pregnancy for improving perinatal outcomes
da Silva Lopes, K, Takemoto, Y, Ota, E, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
9
No studies
3
Included studies
NR
No studies 3 · 25%Ungraded 0 · 0%Very low 0 · 0%Low 9 · 75%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Strict bed rest with and without hospitalisation in multiple pregnancy for improving outcomes
Population: women with multiple pregnancy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Very preterm birth (less than 34 weeks) ‐ assuming complete correlation between twins/triplets | RR 1.02 [0.66, 1.58] | 5 studies · 495 participants | Low |
Perinatal mortality ‐ assuming independence between twins/triplets | RR 0.65 [0.35, 1.21] | 5 studies · 1016 participants | Low |
Low birthweight (less than 2500 g) ‐ assuming independence between twins/triplets | RR 0.95 [0.75, 1.21] | 3 studies · 502 participants | Low Downgraded: risk of bias, inconsistency |
Prelabour preterm rupture of the membrane | RR 1.3 [0.71, 2.38] | 3 studies · 276 participants | Low |
Small‐for‐gestational age ‐ assuming independence between twins/triplets | RR 0.75 [0.56, 1.01] | 2 studies · 293 participants | Low |
Psychosocial effects of bed rest (depression, anxiety, stress) | no estimate extracted | NR | No studies |
Partial bed rest with or without hospitalisation in multiple pregnancy for improving outcomes
Population: women with multiple pregnancy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Very preterm birth (less than 34 weeks) ‐ assuming complete correlation between twins | RR 2.3 [0.84, 6.27] | 1 study · 141 participants | Low Downgraded: risk of bias, imprecision |
Perinatal mortality ‐ assuming independence between twins | RR 4.17 [0.9, 19.31] | 1 study · 282 participants | Low Downgraded: risk of bias, imprecision |
Low birthweight (less than 2500 g) ‐ assuming independence between twins/triplets | no estimate extracted | NR | No studies |
Prelabour preterm rupture of the membrane | RR 1.51 [0.69, 3.3] | 1 study · 141 participants | Low Downgraded: risk of bias, imprecision |
Small‐for‐gestational age ‐ assuming independence between twins | RR 0.93 [0.69, 1.26] | 1 study · 282 participants | Low Downgraded: risk of bias, imprecision |
Psychosocial effects of bed rest (depression, anxiety, stress) | no estimate extracted | NR | No studies |