Non-Cochrane · prognostic · PM42117690
Resonance Frequency Analysis and Clinical Outcomes in Implant Dentistry: A Systematic Review and Meta-Analysis.
Tisci Angela, Fanelli Francesco, Caponio Vito Carlo Alberto, et al. · Clinical implant dentistry and related research · 2026 · PubMed · doi:10.1111/cid.70156
Findings
Population Systemically healthy adults undergoing dental implant placement
33 findings
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Levin et al., 2016 | Pearson r 0.454 [0.333, 0.560] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Implant position: Anterior region | Pearson r 0.4760257 [0.201, 0.681] GRADE not reported 2 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: no VIF correction | Pearson r 0.43 [0.32, 0.54] GRADE not reported 21 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Loading protocol: Early loading | Pearson r 0.7551383 [0.614, 0.849] GRADE not reported 2 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Degidi et al., 2012 | Pearson r 0.448 [0.322, 0.558] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Barewal et al., 2012 | Pearson r 0.431 [0.302, 0.544] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Turkyilmaz et al., 2008 | Pearson r 0.403 [0.289, 0.506] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Malchiodi et al., 2016 | Pearson r 0.422 [0.295, 0.534] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Carosi et al., 2025 | Pearson r 0.423 [0.297, 0.535] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting de Moreas Ferreira et al., 2025 | Pearson r 0.450 [0.327, 0.558] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) | Pearson r 0.44 [0.32, 0.55] Very low Downgraded: risk of bias, inconsistency 20 studies · 6160 implants participants |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Do Vale Souza et al., 2021 | Pearson r 0.435 [0.307, 0.547] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Regeneration: Regenerated sites | Pearson r 0.48362 [-0.070, 0.809] GRADE not reported 3 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Dkheel et al., 2024 | Pearson r 0.433 [0.306, 0.545] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: trim-and-fill | Pearson r 0.46 [0.34, 0.57] GRADE not reported 20 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Degidi et al., 2010 | Pearson r 0.446 [0.318, 0.557] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Regeneration: No regeneration | Pearson r 0.3927642 [0.261, 0.509] GRADE not reported 16 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Sarafaz et al., 2018 | Pearson r 0.435 [0.309, 0.550] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Park et al., 2012 | Pearson r 0.436 [0.308, 0.549] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Baldi et al., 2018 | Pearson r 0.432 [0.303, 0.546] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Loading protocol: Delayed loading | Pearson r 0.3953134 [0.271, 0.505] GRADE not reported 9 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Implant position: Posterior region | Pearson r 0.4441092 [0.222, 0.622] GRADE not reported 9 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Bergamo et al., 2021 | Pearson r 0.427 [0.298, 0.540] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Feng et al., 2023 | Pearson r 0.456 [0.338, 0.559] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Park et al., 2019 | Pearson r 0.437 [0.309, 0.549] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting da Rocha Ferreira et al., 2022 | Pearson r 0.445 [0.318, 0.555] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Surgical protocol: Two-stage surgery | Pearson r 0.5649868 [0.377, 0.708] GRADE not reported 3 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Zita Gomes et al., 2017 | Pearson r 0.407 [0.290, 0.513] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Badenes-Catalán and Pallarés-Sabater, 2021 | Pearson r 0.436 [0.306, 0.550] GRADE not reported 19 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Surgical protocol: One-stage surgery | Pearson r 0.4488072 [0.236, 0.620] GRADE not reported 9 studies |
| Implant stability quotient (ISQ, resonance frequency analysis) at implant placement | Insertion torque (IT) as the correlated measure | Pearson correlation (r) between ISQ and insertion torque ISQ at implant placement (T0) · Sensitivity: leave-one-out omitting Simmons et al., 2017 | Pearson r 0.451 [0.329, 0.558] GRADE not reported 19 studies |
| Baseline ISQ of surviving implants | Baseline ISQ of failed implants | Mean difference in baseline ISQ between surviving and failed implants ISQ at baseline (implant placement) | MD 10.22 [-2.14, 22.58] Very low Downgraded: imprecision, inconsistency 3 studies · 769 implants participants |
| Baseline ISQ of surviving implants | Baseline ISQ of failed implants | Mean difference in baseline ISQ between surviving and failed implants ISQ at baseline (implant placement) · Sensitivity: leave-one-out (range of pooled MD 4.92 to 15.74) | Leave-one-out mean differences ranged from 4.92 to 15.74, with significance varying by the study omitted GRADE not reported 2 studies |
Included primary studies 96
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Badenes‐Catalán and Pallarés‐Sabater, 2021 Congenital adrenal hyperplasia: simultaneous determination of plasma aldosterone and 17-hydroxyprogesterone. PMID:202131 | 1978 | 3 other reviews | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Bergamo et al., 2021 Induction of premature parturition in sheep: adrenocorticotrophin and corticosteroid changes during infusion of Synacthen into the foetus. PMID:202133 | 1978 | 3 other reviews | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Dkheel et al., 2024 Histotoxic effects of polybrominated biphenyls in Michigan dairy cattle. PMID:202450 | 1978 | 2 other reviews | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Feng et al., 2023 [Analysis of the nucleotide sequence of DNA]. PMID:202344 | 1977 | 2 other reviews | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Ab Rahman et al., 2019 Congenital cytomegalovirus disease. Is prevention possible? PMID:201966 | 1977 | 1 other review | not stated | not extracted yet |
| Atieh et al., 2014 The pharmacological profile of norgestimate, a new orally active progestin. PMID:201429 | 1977 | 1 other review | not stated | not extracted yet |
| Baldi et al., 2018 The effects of smoking on immunocompetence. PMID:201813 | 1978 | 1 other review | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Cassetta et al., 2022 Corticosteroids in the treatment of Sydenham's chorea. PMID:202236 | 1978 | 1 other review | not stated | not extracted yet |
| Chen et al., 2019 MSH/ACTH4-10 influences on the CAR in human subjects: a negative finding. PMID:201937 | 1977 | 1 other review | Mean difference in baseline ISQ between surviving and failed implants | not extracted yet |
| da Rocha Ferreira et al., 2022 Viral pathogenesis and molecular biology. PMID:202238 | 1977 | 1 other review | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| de Moraes Ferreira et al., 2025 The histoenzymic activity of gyrus cinguli in the course of postnatal ontogeny of the rat. PMID:202545 | 1977 | 1 other review | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Degidi et al., 2012 Alterations of pulmonary vascular resistance and pulmonary cyclic nucleotide metabolism in the hypoxic pig. PMID:201240 | 1977 | 1 other review | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Dragonas et al., 2020 [Drug misuse and heterodox healing in imperial China. Selected materials on legislation and jurisprudence]. PMID:202043 | 1977 | 1 other review | not stated | not extracted yet |
| Fischer et al., 2009 The pathogenesis of endocrine exophthalmos: a short review. PMID:200947 | 1977 | 1 other review | not stated | not extracted yet |
| Gehrke et al., 2023 [Effect of high temperature on the direct cortical response]. PMID:202348 | 1977 | 1 other review | not stated | not extracted yet |
| Kim et al., 2025 Factors affecting the interferon sensitivity of human cytomegalovirus. PMID:202571 | 1978 | 1 other review | not stated | not extracted yet |
| Noaman and Bede, 2022 Murine cytomegalovirus infection in a non-permissive line of mouse fibroblasts. PMID:202228 | 1977 | 1 other review | not stated | not extracted yet |
| Norton et al., 2017 1,2,4-Triazole amino nucleosides. 1-beta-D-3'-Amino-3'-deoxyribofuranosyl-1,2,4-triazole-3-carboxamide and related nucleosides. PMID:201758 | 1977 | 1 other review | not stated | not extracted yet |
| Park et al., 2019 [Participation of the cAMP system in the radioprotective effect]. PMID:201961 | 1977 | 1 other review | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Ab Rahman et al., 2019 Periodic Assessment of Peri-implant Tissue Changes: Imperative for Implant Success. PMID:31058631 | 2019 | this review only | not stated | not extracted yet |
| Atieh et al., 2014 The prognostic accuracy of resonance frequency analysis in predicting failure risk of immediately restored implants. PMID:23113597 | 2014 | this review only | not stated | not extracted yet |
| Back et al., 2025 The regulation of cellular slime mold development: a factor causing development of Polysphondylium violaceum aggregation-defective mutants. PMID:202530 | 1978 | this review only | not stated | not extracted yet |
| Back et al., 2025 Stability Comparison of Implants with Alumina Sandblasting and Acid Etching Surface Treatment: A Retrospective Cohort Study. PMID:39941411 | 2025 | this review only | not stated | not extracted yet |
| Badenes‐Catalán and Pallarés‐Sabater, 2021 Influence of Smoking on Dental Implant Osseointegration: A Radiofrequency Analysis of 194 Implants. PMID:32699886 | 2021 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Baldi et al., 2018 Correlation between Insertion Torque and Implant Stability Quotient in Tapered Implants with Knife-Edge Thread Design. PMID:29862286 | 2018 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Bannwart et al., 2024 Biochemical background of atherosclerotic heart lesion in an experiment. PMID:202432 | 1977 | this review only | not stated | not extracted yet |
| Bannwart et al., 2024 Influence of torque and bone type on stability quotient of two implant platforms: a clinical trial. PMID:38922209 | 2024 | this review only | not stated | not extracted yet |
| Barewal et al., 2012 The in vivo effects of quartz on rat thoracic lymph nodes. PMID:201263 | 1977 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Barewal et al., 2012 A randomized controlled clinical trial comparing the effects of three loading protocols on dental implant stability. PMID:22848898 | 2012 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Bergamo et al., 2021 Osseodensification effect on implants primary and secondary stability: Multicenter controlled clinical trial. PMID:34047046 | 2021 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Brouwers et al., 2021 [Attempts to establish an immunoprevention of transmissible gastroenteritis (TGE) in swine. I. Pathogenicity of the B1 strain following… PMID:202115 | 1977 | this review only | not stated | not extracted yet |
| Brouwers et al., 2021 Resonance frequency analysis with two different devices after conventional implant placement with ridge preservation: A prospective pilot… PMID:34312973 | 2021 | this review only | not stated | not extracted yet |
| Canullo et al., 2024 Human papillomaviruses and their possible role in squamous cell carcinomas. PMID:202434 | 1977 | this review only | not stated | not extracted yet |
| Canullo et al., 2024 Nano-superhydrophilic and bioactive surface in poor bone environment. Part 1: transition from primary to secondary stability. A controlled… PMID:38872049 | 2024 | this review only | not stated | not extracted yet |
| Carosi et al., 2025 Effect of 1-(2-chloroethyl)-3-(beta-D-glucopyranosyl)-1-nitrosourea on experimental tumors. PMID:202535 | 1977 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Carosi et al., 2025 Effect of time and local factors on the stability of hydrophilic self-tapping tissue-level implants: 1-year prospective study. PMID:40919762 | 2025 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Cassetta et al., 2022 Are the Insertion Torque Value and Implant Stability Quotient Correlated, and If So, Can Insertion Torque Values Predict Secondary Implant… PMID:35235632 | 2022 | this review only | not stated | not extracted yet |
| Chen et al.,2019 Resonance Frequency Analysis in Assessing Implant Stability: A Retrospective Analysis. PMID:31283807 | 2019 | this review only | Mean difference in baseline ISQ between surviving and failed implants | not extracted yet |
| da Rocha Ferreira et al., 2022 Insertion Torque Value and Implant Stability Quotient: Separate Evaluation and Correlation for Different Clinical Parameters. PMID:35904839 | 2022 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| de Moraes Ferreira et al., 2025 Changes in stability and marginal bone level around implants with hydrophilic and hydrophobic surfaces for posterior tooth replacement: A… PMID:40101852 | 2025 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| De Santis et al., 2016 Cellular RNA synthesis in normal and mengovirus-infected L-929 cells. PMID:201639 | 1978 | this review only | not stated | not extracted yet |
| De Santis et al., 2016 Relationship Between Primary Stability and Crestal Bone Loss of Implants Placed with High Insertion Torque: A 3-Year Prospective Study. PMID:27632269 | 2016 | this review only | not stated | not extracted yet |
| Degidi et al., 2010 [Effect of thyroxine, insulin and cholesterol on the amount of cyclic adenosine monophosphate in normal and oncornavirus infected cells]. PMID:201057 | 1977 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Degidi et al., 2010 Determination of primary stability: a comparison of the surgeon's perception and objective measurements. PMID:20556255 | 2010 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Degidi et al., 2012 Primary stability determination by means of insertion torque and RFA in a sample of 4,135 implants. PMID:20849539 | 2012 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Dias et al., 2015 Rehabilitation of the elderly cardiac patient hampered by bias. PMID:201541 | 1977 | this review only | not stated | not extracted yet |
| Dias et al., 2015 The effect of marginal bone level changes on the stability of dental implants in a short-term evaluation. PMID:24893883 | 2015 | this review only | not stated | not extracted yet |
| Dkheel et al., 2024 matched by author and year (probable) | NR | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Do Vale Souza et al., 2021 Changes in conditioned reflex behaviour and brain monoamines to ACTH administration. PMID:202142 | 1977 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Do Vale Souza et al., 2021 Relation Between Insertion Torque and Implant Stability Quotient: A Clinical Study. PMID:34233364 | 2021 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Dragonas et al., 2020 One-year implant survival following lateral window sinus augmentation using plasma rich in growth factors (PRGF): a retrospective study. PMID:32142503 | 2020 | this review only | not stated | not extracted yet |
| Feng et al., 2023 Associations between cortical bone-to-implant contact and microstructure derived from CBCT and implant primary stability. PMID:36727924 | 2023 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Filho et al., 2014 [Participation of cyclic-3',5'-adenosine monophosphate in the pathogenesis of myocardial hypertrophy in experimental hypertension]. PMID:201446 | 1977 | this review only | not stated | not extracted yet |
| Filho et al., 2014 Assessment of the correlation between insertion torque and resonance frequency analysis of implants placed in bone tissue of different… PMID:24914911 | 2014 | this review only | not stated | not extracted yet |
| Fischer et al., 2009 Immediate and early loading of oxidized tapered implants in the partially edentulous maxilla: a 1-year prospective clinical, radiographic,… PMID:18384399 | 2009 | this review only | not stated | not extracted yet |
| Gehrke et al., 2023 Randomized Clinical Trial Comparing Insertion Torque and Implant Stability of Two Different Implant Macrogeometries in the Initial Periods… PMID:36676792 | 2023 | this review only | not stated | not extracted yet |
| Homma et al., 2018 Cell transformation with herpes simplex viruses. PMID:201849 | 1977 | this review only | not stated | not extracted yet |
| Homma et al., 2018 Prospective multicenter non-randomized controlled study on intraosseous stability and healing period for dental implants in the posterior… PMID:29594820 | 2018 | this review only | not stated | not extracted yet |
| Karabuda et al., 2011 Differentiation of human neuroblastoma cells in vitro--morphological changes induced by dibutyrl cyclic AMP. PMID:201151 | 1977 | this review only | not stated | not extracted yet |
| Karabuda et al., 2011 Stability, marginal bone loss and survival of standard and modified sand-blasted, acid-etched implants in bilateral edentulous spaces: a… PMID:21198901 | 2011 | this review only | not stated | not extracted yet |
| Kim et al., 2015 Primary action of steroid hormone at the surface of amphibian oocyte in the induction of germinal vesicle breakdown. PMID:201517 | 1977 | this review only | not stated | not extracted yet |
| Kim et al., 2015 Resonance frequency analysis as a predictor of early implant failure in the partially edentulous posterior maxilla following immediate… PMID:24325547 | 2015 | this review only | not stated | not extracted yet |
| Kim et al., 2025 Impact of Plasma Surface Treatment on Implant Stability and Early Osseointegration: A Retrospective Cohort Study. PMID:41095392 | 2025 | this review only | not stated | not extracted yet |
| Ko et al., 2025 Mitochondria and biological mineralization processes: an exploration. PMID:202553 | 1977 | this review only | not stated | not extracted yet |
| Ko et al., 2025 Clinical evaluation of implants placed within or beyond the boundaries of the alveolar ridge preservation: a retrospective case series… PMID:39058351 | 2025 | this review only | not stated | not extracted yet |
| Levin et al., 2016 The role of butyrate in the reverse transformation reaction in mammalian cells. PMID:201654 | 1978 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Levin et al., 2016 The Correlation Between Immediate Implant Insertion Torque and Implant Stability Quotient. PMID:27740644 | 2016 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Lombardi et al., 2025 Spin labels and biological membranes. PMID:202555 | 1977 | this review only | not stated | not extracted yet |
| Lombardi et al., 2025 Clinical Outcomes of Bone-Level and Tissue-Level Short Implants Placed in Posterior Maxilla: A Case-Control Study. PMID:39676168 | 2025 | this review only | not stated | not extracted yet |
| Malchiodi et al., 2016 Role of Ca2+ in preserving viability of Friend erythroleukaemic cells after ultramicroinjection. PMID:201656 | 1977 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Malchiodi et al., 2016 Primary and Secondary Stability of Implants in Postextraction and Healed Sites: A Randomized Controlled Clinical Trial. PMID:27861670 | 2016 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Noaman and Bede, 2022 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Norton et al., 2017 The Influence of Low Insertion Torque on Primary Stability, Implant Survival, and Maintenance of Marginal Bone Levels: A Closed-Cohort… PMID:28708918 | 2017 | this review only | not stated | not extracted yet |
| Pardo‐Zamora et al., 2021 Morphology and hormonal responsiveness of renal cortical tubules in vitro. PMID:202159 | 1977 | this review only | not stated | not extracted yet |
| Pardo‐Zamora et al., 2021 Short Dental Implants (≤8.5 mm) versus Standard Dental Implants (≥10 mm): A One-Year Post-Loading Prospective Observational Study. PMID:34073250 | 2021 | this review only | not stated | not extracted yet |
| Park et al., 2012 Chromosome complement and SV40 transformation of cells from patients susceptible to malignant disease. PMID:201260 | 1977 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Park et al., 2012 The relationship between implant stability quotient values and implant insertion variables: a clinical study. PMID:21923718 | 2012 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Park et al., 2019 Resonance Frequency Analysis of Tapered Implants Placed at Maxillary Posterior Sites After Lateral Sinus Augmentation: A 1.5-year… PMID:30640311 | 2019 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Rabel et al., 2007 Induction of hepatic tumors in a teleost (Oryzias latipes) after treatment with methylazoxymethanol acetate: brief communication. PMID:200762 | 1977 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Rabel et al., 2007 Clinical study on the primary stability of two dental implant systems with resonance frequency analysis. PMID:17401588 | 2007 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Rosen et al., 2018 Foot-shock induced stress increases beta-endorphin levels in blood but not brain. PMID:201864 | 1977 | this review only | Mean difference in baseline ISQ between surviving and failed implants | not extracted yet |
| Rosen et al., 2018 A 1-7 year retrospective follow-up on consecutively placed 7-mm-long dental implants with an electrowetted surface. PMID:30136010 | 2018 | this review only | Mean difference in baseline ISQ between surviving and failed implants | not extracted yet |
| Sarfaraz et al., 2018 alpha Adrenoreceptors but not beta adrenoreceptors increase in rabbit uterus with oestrogen. PMID:201865 | 1977 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Sarfaraz et al., 2018 Study to assess the relationship between insertion torque value and implant stability quotient and its influence on timing of functional… PMID:29692567 | 2018 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Simmons et al., 2017 Polybrominated biphenyls: inducers of hepatic microsomal enzymes and type A cytochrome P450 in the rat. PMID:201767 | 1977 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Simmons et al., 2017 Comparative evaluation of the stability of two different dental implant designs and surgical protocols-a pilot study. PMID:28466248 | 2017 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Tan et al., 2025 [What is certain in the chemotherapy of solid tumors?]. PMID:202568 | 1977 | this review only | not stated | not extracted yet |
| Tan et al., 2025 Time-dependent changes in implant stability and the influence of clinical parameters: A 12-week resonance frequency analysis-based study. PMID:40947098 | 2026 | this review only | not stated | not extracted yet |
| Turkyilmaz and McGlumphy, 2008 Influence of bone density on implant stability parameters and implant success: a retrospective clinical study. PMID:19025637 | 2008 | this review only | Pearson correlation (r) between ISQ and insertion torque; Mean difference in baseline ISQ between surviving and failed implants | not extracted yet |
| Turkyilmaz et al., 2008 matched by author and year (probable) | NR | this review only | Pearson correlation (r) between ISQ and insertion torque; Mean difference in baseline ISQ between surviving and failed implants | not extracted yet |
| Turkyilmaz et al., 2008 Prevalence of precipitating antibodies to avian adenoviruses in diagnostic serums. PMID:200869 | 1977 | this review only | not stated | not extracted yet |
| Turkyilmaz et al., 2008 Two alternative surgical techniques for enhancing primary implant stability in the posterior maxilla: a clinical study including bone… PMID:18384409 | 2008 | this review only | not stated | not extracted yet |
| Waechter et al., 2017 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Waechter et al., 2017 Comparison between tapered and cylindrical implants in the posterior regions of the mandible: A prospective, randomized, split-mouth… PMID:28557376 | 2017 | this review only | not stated | not extracted yet |
| Zita Gomes et al., 2017 Plasma osmolality and electrolytes during the post partum months in Ghanaian women. PMID:201770 | 1977 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
| Zita Gomes et al., 2017 Implant Stability in the Posterior Maxilla: A Controlled Clinical Trial. PMID:28626763 | 2017 | this review only | Pearson correlation (r) between ISQ and insertion torque | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Systemically healthy human adults (over 18 years) undergoing implant placement for partial edentulism; minimum 20 patients per study | 48 studies, 3631 participants, over 8000 implants; mean age mostly 50 to 60 years; maxilla and mandible |
| Intervention | Quantification of ISQ by resonance frequency analysis during implant therapy | ISQ by Osstell (most studies) or Penguin RFA (2 studies); IT meta-analysis 20 studies (6160 implants); survival meta-analysis 3 studies (769 implants) |
| Comparison | Not applicable (association/prognostic question; no comparator) | Not applicable (correlation; failed versus surviving implants for survival) |
| Outcomes | Association of ISQ with insertion torque, marginal bone loss, implant survival and implant success | ISQ-IT pooled r = 0.44 (0.32-0.55; I2 93.3%); ISQ-survival MD 10.22 (-2.14 to 22.58); MBL and implant success not pooled |
| Study designs | RCTs, prospective and retrospective cohorts, case-control studies, comparative and single-arm observational studies, case series | RCTs, CCTs, prospective and retrospective cohorts, cross-sectional studies, case series (2007 to 2025) |
| Timing | ISQ at implant placement and follow-up time points | Implant placement (T0) up to 10 years follow-up |