Non-Cochrane · DTA · PM42290012

Accuracy and Reliability of Dental Age Estimation Methods in Iranian Children: A Systematic Review and Meta-Analysis.

Jabbarian Razieh, Ranjbaran Mehdi, Mokhlesi Aida · BioMed research international · 2026 · PubMed · doi:10.1155/bmri/9351167

Findings

12 findings

Population
Iranian children aged 3-18 years with dental radiographsDemirjian method of dental age (DA) estimationChronological age (CA)Mean dental age by Demirjian (years)
Iran (panoramic radiographs) · Females
MEAN 10.195 [9.244, 11.147]
GRADE not reported
Studies not reported
Iranian children aged 3-18 years with dental radiographsDemirjian method of dental age (DA) estimationChronological age (CA)Mean difference CA-DA (years)
Iran (panoramic radiographs) · Sensitivity: omitting Javadinejad 2015
MD -0.33 [-0.46, -0.21]
GRADE not reported
11 studies
Iranian children aged 3-18 years with dental radiographsDemirjian method of dental age (DA) estimationChronological age (CA)Mean chronological age (years)
Iran (panoramic radiographs) · Males
MEAN 9.467 [8.281, 10.653]
GRADE not reported
Studies not reported
Iranian children aged 3-18 years with dental radiographsDemirjian method of dental age (DA) estimationChronological age (CA)Mean chronological age (years)
Iran (panoramic radiographs) · Females
MEAN 9.875 [8.800, 10.949]
GRADE not reported
Studies not reported
Iranian children aged 3-18 years with dental radiographsDemirjian method of dental age (DA) estimationChronological age (CA)Mean difference CA-DA (years)
Iran (panoramic radiographs) · Overall (males and females)
MD -0.40 [-0.56, -0.23]
GRADE not reported
12 studies
Iranian children aged 3-18 years with dental radiographsDemirjian method of dental age (DA) estimationChronological age (CA)Mean difference CA-DA (years)
Iran (panoramic radiographs) · Sensitivity: omitting Talaeipour 2022
MD -0.44 [-0.61, -0.27]
GRADE not reported
11 studies
Iranian children aged 3-18 years with dental radiographsDemirjian method of dental age (DA) estimationChronological age (CA)Mean dental age by Demirjian (years)
Iran (panoramic radiographs) · Males
MEAN 10.243 [9.265, 11.221]
GRADE not reported
Studies not reported
Iranian children aged 3-18 years with dental radiographsDemirjian method of dental age (DA) estimationChronological age (CA)Mean difference CA-DA (years)
Iran (panoramic radiographs) · Females
MD -0.323 [-0.468, -0.178]
GRADE not reported
14 studies
Healthy Iranian children and adolescents aged 3-18 years with dental radiographsDemirjian's dental age estimation methodChronological ageMean difference CA minus DA (years)
Iran; panoramic radiographs of seven left permanent mandibular teeth · Overall, sex-stratified estimates combined (Figure 3 overall diamond)
MD -0.52 [-0.66, -0.37]
GRADE not reported
14 studies
Iranian children aged 3-18 years with dental radiographsDemirjian method of dental age (DA) estimationChronological age (CA)Mean dental age by Demirjian (years)
Iran (panoramic radiographs) · Overall (males and females)
MEAN 10.29 [9.16, 11.42]
GRADE not reported
Studies not reported
Iranian children aged 3-18 years with dental radiographsDemirjian method of dental age (DA) estimationChronological age (CA)Mean difference CA-DA (years)
Iran (panoramic radiographs) · Males
MD -0.784 [-1.087, -0.482]
GRADE not reported
14 studies
Iranian children aged 3-18 years with dental radiographsDemirjian method of dental age (DA) estimationChronological age (CA)Mean chronological age (years)
Iran (panoramic radiographs) · Overall (males and females)
MEAN 9.88 [8.65, 11.11]
GRADE not reported
Studies not reported

Included primary studies 50

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Abesi 2013
Hydrolysis of triphosphoinositides in developing central and peripheral nervous systems of the chicken.
PMID:201341
19772 other reviewsMean difference CA-DA (years)not extracted yet
Derayatifar 2018
The induction of chromosome aberrations in mouse dictyate oocytes by X-rays and chemical mutagens.
PMID:201837
19772 other reviewsnot statednot extracted yet
Bagherian 2011
[Plastic reorganization of the activity of sensorimotor cortex neurons during elaboration of a cellular analog of a temporary connection].
PMID:201124
19771 other reviewMean difference CA-DA (years)not extracted yet
Bagherpour 2010
Free radical increases in cancer: evidence that there is not a real increase.
PMID:201025
19771 other reviewMean difference CA-DA (years)not extracted yet
Barati 2022
Rescue of host-dependent conditional lethal mutants of vaccinia and rabbitpox viruses by yaba virus. Brief report.
PMID:202231
19771 other reviewnot statednot extracted yet
Hedayati 2014
[Gonadotropin receptors].
PMID:201442
19771 other reviewMean difference CA-DA (years)not extracted yet
Javadi Nejad 2013
Bell's palsy and herpes simplex.
PMID:201338
19771 other reviewnot statednot extracted yet
Kamali-Sabeti 2018
The effects of smoking on immunocompetence.
PMID:201813
19781 other reviewMean difference CA-DA (years)not extracted yet
Abesi 2013
matched by author and year (probable)
NRthis review onlyMean difference CA-DA (years)not extracted yet
Anbiaee 2013
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
Anbiaee 2013
Cannabis, catecholamines, rapid eye movement sleep and aggressive behaviour.
PMID:201320
1977this review onlynot statednot extracted yet
Bagherian 2011
Assessment of dental maturity of children aged 3.5 to 13.5 years using the Demirjian method in an Iranian population
DOI:10.2334/josnusd.53.37
2011this review onlyMean difference CA-DA (years)not extracted yet
Bagherpour 2010
Dental age assessment among Iranian children aged 6–13 years using the Demirjian method
DOI:10.1016/j.forsciint.2009.12.051
2010this review onlyMean difference CA-DA (years)not extracted yet
Barati 2022
Comparison of Demirjian and Willems Methods in Estimating Dental Age and Modification of Willems Method for 7 - 15 Year Olds Iranian…
DOI:10.5812/ijp-122126
2022this review onlynot statednot extracted yet
Derayatifar 2019
Investigating the Age of the Formation of Permanent Teeth in the Mandible in 5- to 16-Year-Old Children; A Study in Mashhad, Iran
DOI:10.34172/ajdr.2019.02
2019this review onlynot statednot extracted yet
Eshghi 2011
matched by author and year (probable)
NRthis review onlyMean difference CA-DA (years)not extracted yet
Eshghi 2011
S-100 protein and 2',3'-cyclic nucleotide 3'-phosphohydrolase in human brain tumors.
PMID:201144
1977this review onlyMean difference CA-DA (years)not extracted yet
Ghafari 2019
Comparison of the accuracy of the London atlas and Smith method in dental age estimation in 5–15.99-year-old Iranians using the panoramic…
DOI:10.1007/s00414-018-1808-6
2018this review onlynot statednot extracted yet
Ghafari 2019
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
Hedayati 2014
Effect of dexamethasone on pulmonary surfactant metabolism in hyperoxia-treated rat lungs.
PMID:2014154
1991this review onlyMean difference CA-DA (years)not extracted yet
Javadi Nejad 1391 (Cameriere)
Comprehensive rehabilitation of patients having chronic low back pain.
PMID:139136
1977this review onlynot statednot extracted yet
Javadi Nejad 2008
DOI:10.22038/jmds.2010.1195
NRthis review onlyMean difference CA-DA (years)not extracted yet
Javadi Nejad 2008 (1387)
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
Javadi Nejad 2013
DOI:10.22038/jmds.2013.1880
NRthis review onlyMean difference CA-DA (years)not extracted yet
Javadinejad 2010
matched by author and year (probable)
NRthis review onlyMean difference CA-DA (years)not extracted yet
Javadinejad 2012
DOI:10.48305/v8i4.532
NRthis review onlynot statednot extracted yet
Javadinejad 2015
A Comparison of the Accuracy of Four Age Estimation Methods Based on Panoramic Radiography of Developing Teeth
DOI:10.15171/joddd.2015.015
2015this review onlyMean difference CA-DA (years)not extracted yet
Javadinejad 2015
Rapid conversion by insulin of hepatic intermediary metabolism from glucose production to glucose utilization in the liver of…
PMID:201529
1977this review onlyMean difference CA-DA (years)not extracted yet
Kamali-Sabeti 2018
matched by author and year (probable)
NRthis review onlyMean difference CA-DA (years)not extracted yet
Kermani 2019
Evaluation of the accuracy of Demirjian's method for estimating chronological age from dental age in Shiraz, Iran: Using geometric…
DOI:10.1002/cre2.169
2019this review onlynot statednot extracted yet
Kermani 2019
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
Mohtavipour 2017
Dental Age Estimation of 6-14-Year-Old Guilanian Children Using Demirjian’s Method
DOI:10.5812/ajdr.12510
2017this review onlyMean difference CA-DA (years)not extracted yet
Movahedian 2018
matched by author and year (probable)
NRthis review onlyMean difference CA-DA (years)not extracted yet
Movahedian 2018
p-Chlorophenoxyisobutyrate enhanced retention of homologous lipoproteins by human aortic smooth muscle cells.
PMID:201816
1977this review onlyMean difference CA-DA (years)not extracted yet
Namadchian 2022
A Comparison of Demirjian and Cameriere Methods in Estimating Age and Development of a Modified Cameriere Method
DOI:10.5812/semj.117342
2021this review onlyMean difference CA-DA (years)not extracted yet
Namadchian 2022
matched by author and year (probable)
NRthis review onlyMean difference CA-DA (years)not extracted yet
Naseh 2011
matched by author and year (probable)
NRthis review onlyMean difference CA-DA (years)not extracted yet
Naseh 2016
matched by author and year (probable)
NRthis review onlyMean difference CA-DA (years)not extracted yet
Naseh 2016
Definition of cytochrome c binding domains by chemical modification. I. Reaction with 4-chloro-3,5-dinitrobenzoate and chromatographic…
PMID:201614
1978this review onlyMean difference CA-DA (years)not extracted yet
Naseh 2016 (468 participants)
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
Sheikhi 2012 Babol
DOI:10.48305/v7i5.411
NRthis review onlynot statednot extracted yet
Sheikhi 2013 Rasht
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
Sheykhi 1390 (Babol)
[Significance of body weight in degenerative skeletal diseases (author's transl)].
PMID:139040
1977this review onlynot statednot extracted yet
Sheykhi 1390 (Kerman)
Correlations between renal interstitium and level of serum creatinine. Morphometric investigations of biopsies in perimembranous…
PMID:139021
1977this review onlynot statednot extracted yet
Sheykhi 1390 (Rasht)
[Development and function of endocrine cells in the proventriculus of the chicken (author's transl)].
PMID:139019
1977this review onlynot statednot extracted yet
Tafakhori 2016
matched by author and year (probable)
NRthis review onlyMean difference CA-DA (years)not extracted yet
Tafakhori 2016
Purified cyclic GMP-dependent protein kinase catalyzes the phosphorylation of cardiac troponin inhibitory subunit (TN-1).
PMID:201627
1978this review onlynot statednot extracted yet
Tahereh Mohtavipour 2017
Characterization of the thyroid cell surface by labelling with 125I [proceedings].
PMID:201715
1977this review onlynot statednot extracted yet
Talaeipour 2022
Evaluation of the accuracy of Demirjian method in estimating chronological age
DOI:10.52547/jrds.19.2.159
2022this review onlyMean difference CA-DA (years)not extracted yet
Talaeipour 2022
Some mediator of inflammation increase the permeability coefficient of albumin in the rat mesentery. A probable role for cyclic nucleotides.
PMID:202243
1977this review onlyMean difference CA-DA (years)not extracted yet

Overlap with other reviews

Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.

Review question

ElementPlanned (methods)Found (results)
PopulationIranian children aged 3-18 years, healthy, with all permanent mandibular teethIranian children, 3-20 years, 12 cities/provinces (n=27 studies)
InterventionDental age estimation methods (exposure) using dental radiographsDemirjian (17 studies); Cameriere (3); Willem (3); Smith (2); Nolla (1); London Atlas (1); Moorrees (1)
ComparisonChronological ageChronological age
OutcomesMean difference between chronological age and dental age (accuracy), overall and by sexMean CA-DA: Demirjian overall -0.40 years (95% CI -0.56, -0.23); males -0.784; females -0.323; other methods synthesized narratively
Study designsCross-sectional or retrospective studiesCross-sectional or retrospective studies (n=27)
TimingNot specifiedNot specified