Non-Cochrane · intervention · PM41647248
The Effectiveness of Physical Adjunctive Interventions in the Acceleration of Orthodontic Tooth Movement: An Umbrella Review and Meta-Analysis.
Sirri Mohamad Radwan, Namera Mohammad Osama, Salahi Alasbahi Mohamad Yaman, et al. · International journal of dentistry · 2026 · PubMed · doi:10.1155/ijod/9131541
Findings
34 findings
| Population | ||||
|---|---|---|---|---|
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (leveling and alignment) | AcceleDent vibration device | Standard orthodontic treatment without the adjunctive intervention | Reduction in Little's irregularity index (LII), mm Leveling and alignment · Orthodontic patients; leveling and alignment · Maxilla without extraction | MD 0.21 [-0.52, 0.94] Low Downgraded: risk of bias, imprecision 3 studies · 108 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (leveling and alignment) | AcceleDent vibration device | Standard orthodontic treatment without the adjunctive intervention | Reduction in Little's irregularity index (LII), mm Leveling and alignment · Orthodontic patients; leveling and alignment · Mandible without extraction | MD 0.05 [-0.38, 0.49] Low Downgraded: risk of bias, imprecision 5 studies · 150 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (canine retraction) | Customized vibratory appliance | Standard orthodontic treatment without the adjunctive intervention | Mean canine retraction rate (mm/month) Orthodontic patients; canine retraction | MD 0.15 [-0.03, 0.34] Very low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 96 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (canine retraction) | AcceleDent vibration device | Standard orthodontic treatment without the adjunctive intervention | Mean canine retraction rate (mm/month) Orthodontic patients; canine retraction | MD 0.27 [0.19, 0.35] Very low Downgraded: risk of bias, imprecision, inconsistency 4 studies · 99 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (canine retraction) | Electric toothbrush vibration | Standard orthodontic treatment without the adjunctive intervention | Mean canine retraction at different time points (mm) Month 3 · Orthodontic patients; canine retraction | MD 0.11 [-0.11, 0.33] Very low Downgraded: risk of bias, imprecision, inconsistency 3 studies · 132 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (canine retraction) | Electric toothbrush vibration | Standard orthodontic treatment without the adjunctive intervention | Mean canine retraction at different time points (mm) Month 2 · Orthodontic patients; canine retraction | MD 0.14 [-0.11, 0.4] Very low Downgraded: risk of bias, imprecision, inconsistency 3 studies · 132 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (canine retraction) | Electric toothbrush vibration | Standard orthodontic treatment without the adjunctive intervention | Total canine retraction (mm) Total · Orthodontic patients; canine retraction | MD 0.67 [0.01, 1.32] Very low Downgraded: risk of bias, imprecision, inconsistency 3 studies · 112 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (canine retraction) | Electric toothbrush vibration | Standard orthodontic treatment without the adjunctive intervention | Mean canine retraction at different time points (mm) Month 1 · Orthodontic patients; canine retraction | MD 0.01 [-0.01, 0.02] Very low Downgraded: risk of bias, imprecision, inconsistency 3 studies · 132 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (en masse retraction) | Customized vibratory appliance | Standard orthodontic treatment without the adjunctive intervention | Mean en masse retraction rate (mm/month) Orthodontic patients; en masse retraction · Upper right quadrant | MD 0.19 [-0.25, 0.63] Very low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 65 participants |
| Patients undergoing orthodontic treatment (en masse retraction) | Customized vibratory appliance | No vibration device (standard orthodontic treatment) | Mean en masse retraction rate (mm/month) Orthodontic treatment with fixed or aligner appliances; pooled primary RCTs after removal of overlap among 17 systematic reviews · Upper left | MD 0.29 [-0.44, 1.03] Very low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 65 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (leveling and alignment) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Leveling and alignment improvement percentage, LAIP (%) Week 12 · Orthodontic patients; leveling and alignment · Mandible without extraction | MD 6.7 [-5.48, 18.88] Low Downgraded: risk of bias, imprecision 2 studies · 56 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (leveling and alignment) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Orthodontic leveling and alignment time, OLAT (days) Until alignment · Orthodontic patients; leveling and alignment · Mandible without extraction | MD -58.42 [-88.64, -28.21] Low Downgraded: risk of bias, inconsistency 2 studies · 66 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (leveling and alignment) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Leveling and alignment improvement percentage, LAIP (%) Week 4 · Orthodontic patients; leveling and alignment · Mandible without extraction | MD 2.46 [-4.4, 9.33] Low Downgraded: risk of bias, imprecision 2 studies · 56 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (leveling and alignment) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Leveling and alignment improvement percentage, LAIP (%) Week 8 · Orthodontic patients; leveling and alignment · Mandible without extraction | MD 7.58 [-7.25, 22.41] Low Downgraded: risk of bias, imprecision 2 studies · 56 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Light-emitting diode (LED) therapy | Standard orthodontic treatment without the adjunctive intervention | Monthly upper canine retraction (mm) Month 3 · Orthodontic patients; upper canine retraction | MD -0.06 [-0.59, 0.46] Low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 78 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Light-emitting diode (LED) therapy | Standard orthodontic treatment without the adjunctive intervention | Monthly upper canine retraction (mm) Month 2 · Orthodontic patients; upper canine retraction | MD 0.06 [-0.09, 0.21] Low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 78 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Light-emitting diode (LED) therapy | Standard orthodontic treatment without the adjunctive intervention | Monthly upper canine retraction (mm) Month 1 · Orthodontic patients; upper canine retraction | MD 0.19 [-0.47, 0.86] Low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 78 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Monthly upper canine retraction (mm) Month 3 · Orthodontic patients; upper canine retraction | MD 0.12 [-0.13, 0.37] Low Downgraded: risk of bias, imprecision, inconsistency 4 studies · 90 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Cumulative upper canine retraction from baseline (mm) 21 days · Orthodontic patients; upper canine retraction | MD 0.74 [0.17, 1.31] Low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 66 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Change in upper canine position (mm) Month 1 · Orthodontic patients; upper canine retraction | MD -0.13 [-0.58, 0.32] Very low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 42 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Cumulative upper canine retraction from baseline (mm) Month 3 · Orthodontic patients; upper canine retraction | MD 0.46 [0.06, 0.86] Low Downgraded: risk of bias, imprecision, inconsistency 6 studies · 202 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Change in upper canine position (mm) Month 4 · Orthodontic patients; upper canine retraction | MD -0.67 [-1.99, 0.66] Very low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 36 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Upper canine retraction rate (mm/month) Orthodontic patients; upper canine retraction | MD 0.66 [0.36, 0.96] Low Downgraded: risk of bias, imprecision 6 studies · 227 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Monthly upper canine retraction (mm) Month 2 · Orthodontic patients; upper canine retraction | MD 0.27 [0.08, 0.46] Moderate Downgraded: risk of bias 6 studies · 150 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Change in upper canine position (mm) Month 2 · Orthodontic patients; upper canine retraction | MD -0.41 [-1.24, 0.41] Very low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 42 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Cumulative upper canine retraction from baseline (mm) Month 2 · Orthodontic patients; upper canine retraction | MD 0.72 [0.18, 1.26] Low Downgraded: risk of bias, inconsistency 9 studies · 240 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Cumulative upper canine retraction from baseline (mm) Month 1 · Orthodontic patients; upper canine retraction | MD 0.31 [0.13, 0.49] Low Downgraded: risk of bias, imprecision, inconsistency 14 studies · 354 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Change in upper canine position (mm) Month 3 · Orthodontic patients; upper canine retraction | MD -0.4 [-1.18, 0.39] Very low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 38 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Total upper canine retraction post-treatment (mm) Post-treatment · Orthodontic patients; upper canine retraction | MD 1.08 [0.33, 1.82] Very low Downgraded: risk of bias, imprecision, inconsistency 4 studies · 130 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (lower canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Lower canine retraction rate (mm/month) Orthodontic patients; lower canine retraction | MD 0.58 [0.35, 0.81] Low Downgraded: risk of bias, imprecision 3 studies · 120 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (lower canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Monthly lower canine retraction (mm) Month 2 · Orthodontic patients; lower canine retraction | MD -0.14 [-0.8, 0.51] Low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 44 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (lower canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Monthly lower canine retraction (mm) Month 3 · Orthodontic patients; lower canine retraction | MD -0.06 [-0.74, 0.61] Low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 44 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (lower canine retraction) | Low-level laser therapy (LLLT) | Standard orthodontic treatment without the adjunctive intervention | Monthly lower canine retraction (mm) Month 1 · Orthodontic patients; lower canine retraction | MD 1.03 [0.67, 1.4] Low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 44 participants |
| Patients undergoing orthodontic treatment with fixed or clear aligner appliances (upper canine retraction) | Pulsed electromagnetic field (PEMF) bioelectric stimulation | Standard orthodontic treatment without the adjunctive intervention | Total upper canine retraction post-treatment (mm) Post-treatment · Orthodontic patients; upper canine retraction | MD 1.78 [0.99, 2.57] Low Downgraded: risk of bias, imprecision 2 studies · 58 participants |
Included primary studies 130
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Katchooi 2018 Effect of supplemental vibration on orthodontic treatment with aligners: A randomized trial. PMID:29501108 | 2018 | 2 other reviews | Reduction in Little's irregularity index (LII), mm | not extracted yet |
| Okla 2018 Effect of Photobiomodulation on Maxillary Decrowding and Root Resorption: A Randomized Clinical Trial DOI:10.4103/apos.apos_46_18 | 2018 | 2 other reviews | not stated | not extracted yet |
| Abellán 2021 Effects of Photobiomodulation on the Upper First Molar Intrusion Movement Using Mini-Screws Anchorage: A Randomized Controlled Trial DOI:10.1089/photob.2020.4979 | 2021 | 1 other review | not stated | not extracted yet |
| Alansari 2018 The effects of brief daily vibration on clear aligner orthodontic treatment DOI:10.1016/j.ejwf.2018.10.002 | 2018 | 1 other review | not stated | not extracted yet |
| Bhad 2022 Efficacy of pulsed electromagnetic field in reducing treatment time: A clinical investigation DOI:10.1016/j.ajodo.2020.12.025 | 2022 | 1 other review | not stated | not extracted yet |
| Bragassa 2018 matched by author and year (probable) | NR | 1 other review | not stated | not extracted yet |
| Doshi-Mehta 2012 Efficacy of low-intensity laser therapy in reducing treatment time and orthodontic pain: A clinical investigation DOI:10.1016/j.ajodo.2011.09.009 | 2012 | 1 other review | not stated | not extracted yet |
| Ekizer 2016 Light emitting diode mediated photobiomodulation therapy improves orthodontic tooth movement and miniscrew stability: A randomized… DOI:10.1002/lsm.22516 | 2016 | 1 other review | not stated | not extracted yet |
| Ghaffar 2022 Effect of low-level laser therapy on the time needed for leveling and alignment of mandibular anterior crowding. PMID:35344012 | 2022 | 1 other review | Orthodontic leveling and alignment time, OLAT (days); Leveling and alignment improvement percentage, LAIP (%) | not extracted yet |
| Guram 2018 Evaluation of Low-Level Laser Therapy on Orthodontic Tooth Movement: A Randomized Control Study. PMID:29599594 | 2018 | 1 other review | Upper canine retraction rate (mm/month); Lower canine retraction rate (mm/month) | not extracted yet |
| Katchooi 2018 Effect of supplemental vibration on orthodontic treatment with aligners: A randomized trial DOI:10.1016/j.ajodo.2017.10.017 | 2018 | 1 other review | not stated | not extracted yet |
| Kharat 2023 Accelerated Canine Retraction by Using Mini Implant With Low-Intensity Laser Therapy. PMID:36819422 | 2023 | 1 other review | Upper canine retraction rate (mm/month); Cumulative upper canine retraction from baseline (mm); Total upper canine retraction post-treatment (mm) | not extracted yet |
| Liao 2017 Computational and clinical investigation on the role of mechanical vibration on orthodontic tooth movement DOI:10.1016/j.jbiomech.2017.06.012 | 2017 | 1 other review | not stated | not extracted yet |
| Lombardo 2019 Does low-frequency vibration have an effect on aligner treatment? A single-centre, randomized controlled trial DOI:10.1093/ejo/cjy076 | 2018 | 1 other review | not stated | not extracted yet |
| Lombardo 2019 Does low-frequency vibration have an effect on aligner treatment? A single-centre, randomized controlled trial. PMID:30423130 | 2019 | 1 other review | not stated | not extracted yet |
| Mayama 2022 Effect of vibration on orthodontic tooth movement in a double blind prospective randomized controlled trial DOI:10.1038/s41598-022-05395-5 | 2022 | 1 other review | not stated | not extracted yet |
| Miles 2012 The effects of a vibrational appliance on tooth movement and patient discomfort: a prospective randomised clinical trial. PMID:23304970 | 2012 | 1 other review | not stated | not extracted yet |
| Mistry 2020 The effects of a clinically feasible application of low-level laser therapy on the rate of orthodontic tooth movement: A triple-blind,… DOI:10.1016/j.ajodo.2019.12.005 | 2020 | 1 other review | not stated | not extracted yet |
| Pescheret 2017 matched by author and year (probable) | NR | 1 other review | Reduction in Little's irregularity index (LII), mm | not extracted yet |
| Qamruddin 2017 Effects of low-level laser irradiation on the rate of orthodontic tooth movement and associated pain with self-ligating brackets. PMID:29103440 | 2017 | 1 other review | Cumulative upper canine retraction from baseline (mm) | not extracted yet |
| Souza 2014 matched by author and year (probable) | NR | 1 other review | Monthly upper canine retraction (mm); Cumulative upper canine retraction from baseline (mm); Monthly lower canine retraction (mm) | not extracted yet |
| Üretürk 2017 The effect of low-level laser therapy on tooth movement during canine distalization DOI:10.1007/s10103-017-2159-0 | 2017 | 1 other review | not stated | not extracted yet |
| Varella 2018 Low-level laser therapy increases interleukin-1β in gingival crevicular fluid and enhances the rate of orthodontic tooth movement DOI:10.1016/j.ajodo.2018.01.012 | 2018 | 1 other review | not stated | not extracted yet |
| Abellán 2021 Effects of Photobiomodulation on the Upper First Molar Intrusion Movement Using Mini-Screws Anchorage: A Randomized Controlled Trial. PMID:34328794 | 2021 | this review only | not stated | not extracted yet |
| Al-Shafi 2021 Effect of light-emitting diode–mediated photobiomodulation on extraction space closure in adolescents and young adults: A split-mouth,… DOI:10.1016/j.ajodo.2020.12.021 | 2021 | this review only | not stated | not extracted yet |
| Al-Shafi 2021 Effect of light-emitting diode-mediated photobiomodulation on extraction space closure in adolescents and young adults: A split-mouth,… PMID:33840531 | 2021 | this review only | Monthly upper canine retraction (mm) | not extracted yet |
| Alam 2019 Laser-Assisted Orthodontic Tooth Movement in Saudi Population: A Prospective Clinical Intervention of Low-Level Laser Therapy in the 1st… DOI:10.1155/2019/6271835 | 2019 | this review only | not stated | not extracted yet |
| Alam 2019 Laser-Assisted Orthodontic Tooth Movement in Saudi Population: A Prospective Clinical Intervention of Low-Level Laser Therapy in the 1st… PMID:31772695 | 2019 | this review only | not stated | not extracted yet |
| AlSayed 2017 Low-level laser therapy effectiveness in accelerating orthodontic tooth movement: A randomized controlled clinical trial DOI:10.2319/062716-503.1 | 2017 | this review only | not stated | not extracted yet |
| AlSayed Hasan 2017 Low-level laser therapy effectiveness in accelerating orthodontic tooth movement: A randomized controlled clinical trial. PMID:27869476 | 2017 | this review only | not stated | not extracted yet |
| Arumughan 2018 A Comparison of the Rate of Retraction with Low-level Laser Therapy and Conventional Retraction Technique. PMID:29875571 | 2018 | this review only | not stated | not extracted yet |
| Azeem 2019 Effectiveness of electric toothbrush as vibration method on orthodontic tooth movement: a split-mouth study DOI:10.1590/2177-6709.24.2.049-055.oar | 2019 | this review only | not stated | not extracted yet |
| Azeem 2019 Effectiveness of electric toothbrush as vibration method on orthodontic tooth movement: a split-mouth study. PMID:31116287 | 2019 | this review only | Mean canine retraction at different time points (mm); Total canine retraction (mm) | not extracted yet |
| Barsi 2023 Can bioelectrical stimulation favor orthodontic treatment? A randomized clinical trial to evaluate tooth movement, patient-centered, and… DOI:10.1016/j.xaor.2023.09.004 | 2023 | this review only | not stated | not extracted yet |
| Bhad (Patil) 2022 Efficacy of pulsed electromagnetic field in reducing treatment time: A clinical investigation. PMID:35039203 | 2022 | this review only | Total upper canine retraction post-treatment (mm) | not extracted yet |
| Bisht 2019 To Study the Effect of Vibrations on Pain and Rate of Anterior Teeth Alignment: An Invivo Study DOI:10.18231/j.jco.2019.011 | 2023 | this review only | not stated | not extracted yet |
| Bulic 2017 matched by author and year (probable) | NR | this review only | Reduction in Little's irregularity index (LII), mm | not extracted yet |
| C PSd 2014 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Caccianiga 2016 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Caccianiga 2016 Low-level laser therapy and invisible removal aligners. PMID:27469556 | 2016 | this review only | not stated | not extracted yet |
| Caccianiga 2017 Does Low-Level Laser Therapy Enhance the Efficiency of Orthodontic Dental Alignment? Results from a Randomized Pilot Study DOI:10.1089/pho.2016.4215 | 2017 | this review only | not stated | not extracted yet |
| Caccianiga 2017 Does Low-Level Laser Therapy Enhance the Efficiency of Orthodontic Dental Alignment? Results from a Randomized Pilot Study. PMID:28253073 | 2017 | this review only | Orthodontic leveling and alignment time, OLAT (days) | not extracted yet |
| Chouinard 2016 matched by author and year (probable) | NR | this review only | Reduction in Little's irregularity index (LII), mm | not extracted yet |
| Cruz 2004 Effects of low‐intensity laser therapy on the orthodontic movement velocity of human teeth: A preliminary study DOI:10.1002/lsm.20076 | 2004 | this review only | not stated | not extracted yet |
| Cruz 2004 Effects of low-intensity laser therapy on the orthodontic movement velocity of human teeth: a preliminary study. PMID:15334614 | 2004 | this review only | Cumulative upper canine retraction from baseline (mm) | not extracted yet |
| Dalaie 2015 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Dalaie 2015 Effect of Low-Level Laser Therapy on Orthodontic Tooth Movement: A Clinical Investigation. PMID:26622279 | 2015 | this review only | Cumulative upper canine retraction from baseline (mm); Total upper canine retraction post-treatment (mm) | not extracted yet |
| de SJ 2014 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| DiBiase 2018 Effects of supplemental vibrational force on space closure, treatment duration, and occlusal outcome: A multicenter randomized clinical… DOI:10.1016/j.ajodo.2017.10.021 | 2018 | this review only | not stated | not extracted yet |
| DiBiase 2018 Effects of supplemental vibrational force on space closure, treatment duration, and occlusal outcome: A multicenter randomized clinical… PMID:29602338 | 2018 | this review only | not stated | not extracted yet |
| Domínguez 2015 Effects of low-level laser therapy on orthodontics: rate of tooth movement, pain, and release of RANKL and OPG in GCF DOI:10.1007/s10103-013-1508-x | 2013 | this review only | not stated | not extracted yet |
| Domínguez 2015 Effects of low-level laser therapy on orthodontics: rate of tooth movement, pain, and release of RANKL and OPG in GCF. PMID:24346335 | 2015 | this review only | not stated | not extracted yet |
| Doshi-Mehta 2012 Efficacy of low-intensity laser therapy in reducing treatment time and orthodontic pain: a clinical investigation. PMID:22381489 | 2012 | this review only | Upper canine retraction rate (mm/month); Cumulative upper canine retraction from baseline (mm); Total upper canine retraction post-treatment (mm); Lower canine retraction rate (mm/month) | not extracted yet |
| Ekizer 2016 Light emitting diode mediated photobiomodulation therapy improves orthodontic tooth movement and miniscrew stability: A randomized… PMID:27039894 | 2016 | this review only | Monthly upper canine retraction (mm) | not extracted yet |
| El Shehawy 2020 Outcome of photodynamic therapy on orthodontic leveling and alignment of mandibular anterior segment: A controlled clinical trial DOI:10.1016/j.pdpdt.2020.101903 | 2020 | this review only | not stated | not extracted yet |
| El Shehawy 2020 Outcome of photodynamic therapy on orthodontic leveling and alignment of mandibular anterior segment: A controlled clinical trial. PMID:32619715 | 2020 | this review only | Leveling and alignment improvement percentage, LAIP (%) | not extracted yet |
| Farhadian 2021 The effect of intra-oral LED device and low-level laser therapy on orthodontic tooth movement in young adults: A randomized controlled trial DOI:10.1016/j.ortho.2021.09.002 | 2021 | this review only | not stated | not extracted yet |
| Farhadian 2021 The effect of intra-oral LED device and low-level laser therapy on orthodontic tooth movement in young adults: A randomized controlled… PMID:34607784 | 2021 | this review only | Upper canine retraction rate (mm/month) | not extracted yet |
| Ghaffar 2022 Effect of low-level laser therapy on the time needed for leveling and alignment of mandibular anterior crowding: DOI:10.2319/102721-795.1 | 2022 | this review only | not stated | not extracted yet |
| Gujar 2023 Effect of 125 Hz and 150 Hz vibrational frequency electric toothbrushes on the rate of orthodontic tooth movement and prostaglandin E2… PMID:37746776 | 2023 | this review only | Mean en masse retraction rate (mm/month); PM41647248-P5-O2 | not extracted yet |
| Hasan 2022 Evaluation of the acceleration, skeletal and dentoalveolar effects of low-level laser therapy combined with fixed posterior bite blocks in… DOI:10.1016/j.ortho.2021.10.005 | 2022 | this review only | not stated | not extracted yet |
| Hasan 2022 Evaluation of the acceleration, skeletal and dentoalveolar effects of low-level laser therapy combined with fixed posterior bite blocks in… PMID:34887236 | 2022 | this review only | not stated | not extracted yet |
| Heravi 2014 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Heravi 2014 The effect of low level laser therapy on the rate of tooth movement and pain perception during canine retraction. PMID:24984620 | 2014 | this review only | Monthly upper canine retraction (mm); Cumulative upper canine retraction from baseline (mm) | not extracted yet |
| Hosseini 2011 matched by author and year (probable) | NR | this review only | Cumulative upper canine retraction from baseline (mm) | not extracted yet |
| Impellizzeri 2020 Photobiomodulation Therapy on Orthodontic Movement: Analysis of Preliminary Studies with a New Protocol DOI:10.3390/ijerph17103547 | 2020 | this review only | not stated | not extracted yet |
| Impellizzeri 2020 Photobiomodulation Therapy on Orthodontic Movement: Analysis of Preliminary Studies with a New Protocol. PMID:32438716 | 2020 | this review only | Cumulative upper canine retraction from baseline (mm) | not extracted yet |
| Isola 2019 Effectiveness of Low-Level Laser Therapy during Tooth Movement: A Randomized Clinical Trial. PMID:31288379 | 2019 | this review only | not stated | not extracted yet |
| Kalemaj 2017 Aligning Effectiveness, Secretion of Interleukin 1β and Pain Control During Fixed Orthodontic Treatment with Self-Ligating Appliances and… DOI:10.7150/jbm.17492 | 2017 | this review only | Reduction in Little's irregularity index (LII), mm | not extracted yet |
| Kannan 2019 Effectiveness and importance of powered tooth brushes in tooth movement. PMID:31463280 | 2019 | this review only | Mean canine retraction at different time points (mm) | not extracted yet |
| Kansal 2014 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Kansal 2014 Effects of low-intensity laser therapy on the rate of orthodontic tooth movement: A clinical trial. PMID:25225562 | 2014 | this review only | Monthly upper canine retraction (mm); Cumulative upper canine retraction from baseline (mm) | not extracted yet |
| Kau 2013 Photobiomodulation accelerates orthodontic alignment in the early phase of treatment DOI:10.1186/2196-1042-14-30 | 2013 | this review only | not stated | not extracted yet |
| Kau 2013 Photobiomodulation accelerates orthodontic alignment in the early phase of treatment. PMID:24326198 | 2013 | this review only | not stated | not extracted yet |
| Khera 2022 Effect of customized vibratory device on orthodontic tooth movement: A prospective randomized control trial. PMID:35754416 | 2022 | this review only | Mean canine retraction rate (mm/month) | not extracted yet |
| Kim 2008 The effects of electrical current from a micro-electrical device on tooth movement DOI:10.4041/kjod.2008.38.5.337 | 2008 | this review only | not stated | not extracted yet |
| Kochar 2017 Effect of Low-level Laser Therapy on Orthodontic Tooth Movement DOI:10.1177/0974909820170204 | 2017 | this review only | not stated | not extracted yet |
| Kochar 2017 Effect of Low-level Laser Therapy on Orthodontic Tooth Movement DOI:10.4103/jios.jios_200_16 | 2017 | this review only | Upper canine retraction rate (mm/month); Lower canine retraction rate (mm/month) | not extracted yet |
| Kumar 2020 Comparative assessment of the rate of orthodontic tooth movement in adolescent patients undergoing treatment by first bicuspid extraction… DOI:10.1016/j.ortho.2020.08.003 | 2020 | this review only | not stated | not extracted yet |
| Kumar 2020 Comparative assessment of the rate of orthodontic tooth movement in adolescent patients undergoing treatment by first bicuspid extraction… PMID:33162347 | 2020 | this review only | Mean en masse retraction rate (mm/month); PM41647248-P5-O2 | not extracted yet |
| Lalnunpuii 2020 Comparison of rate of orthodontic tooth movement in adolescent patients undergoing treatment by first bicuspid extraction and en-mass… DOI:10.1016/j.ortho.2020.05.008 | 2020 | this review only | not stated | not extracted yet |
| Lalnunpuii 2020 Comparison of rate of orthodontic tooth movement in adolescent patients undergoing treatment by first bicuspid extraction and en-mass… PMID:32571649 | 2020 | this review only | not stated | not extracted yet |
| Leethanakul 2016 Vibratory stimulation increases interleukin-1 beta secretion during orthodontic tooth movement DOI:10.2319/111914-830.1 | 2016 | this review only | not stated | not extracted yet |
| Leethanakul 2016 Vibratory stimulation increases interleukin-1 beta secretion during orthodontic tooth movement. PMID:25811245 | 2016 | this review only | Mean canine retraction at different time points (mm); Total canine retraction (mm) | not extracted yet |
| Liao 2017 Computational and clinical investigation on the role of mechanical vibration on orthodontic tooth movement. PMID:28743370 | 2017 | this review only | Total canine retraction (mm) | not extracted yet |
| Limpanichkul 2006 Effects of low‐level laser therapy on the rate of orthodontic tooth movement DOI:10.1111/j.1601-6343.2006.00338.x | 2006 | this review only | not stated | not extracted yet |
| Limpanichkul 2006 Effects of low-level laser therapy on the rate of orthodontic tooth movement. PMID:16420273 | 2006 | this review only | Cumulative upper canine retraction from baseline (mm) | not extracted yet |
| Lo Giudice 2020 A Comparative Assessment of the Efficiency of Orthodontic Treatment With and Without Photobiomodulation During Mandibular Decrowding in… DOI:10.1089/photob.2019.4747 | 2020 | this review only | not stated | not extracted yet |
| Lo Giudice 2020 A Comparative Assessment of the Efficiency of Orthodontic Treatment With and Without Photobiomodulation During Mandibular Decrowding in… PMID:31944878 | 2020 | this review only | not stated | not extracted yet |
| Mal 2018 Evaluation of the effects of laser irradiation on the rate of tooth movement: A split-mouth study DOI:10.4103/kleuhsj.kleuhsj_249_17 | 2018 | this review only | Monthly upper canine retraction (mm); Change in upper canine position (mm); Cumulative upper canine retraction from baseline (mm) | not extracted yet |
| Mayama 2022 Effect of vibration on orthodontic tooth movement in a double blind prospective randomized controlled trial. PMID:35079071 | 2022 | this review only | Mean canine retraction rate (mm/month) | not extracted yet |
| Miles 2012 The effects of a vibrational appliance on tooth movement and patient discomfort: a prospective randomised clinical trial DOI:10.2478/aoj-2012-0019 | 2012 | this review only | not stated | not extracted yet |
| Miles 2016 Assessment of the changes in arch perimeter and irregularity in the mandibular arch during initial alignment with the AcceleDent Aura… DOI:10.1016/j.ajodo.2016.07.016 | 2016 | this review only | not stated | not extracted yet |
| Miles 2016 Assessment of the changes in arch perimeter and irregularity in the mandibular arch during initial alignment with the AcceleDent Aura… PMID:27894541 | 2016 | this review only | not stated | not extracted yet |
| Miles 2018 Assessment of the rate of premolar extraction space closure in the maxillary arch with the AcceleDent Aura appliance vs no appliance in… DOI:10.1016/j.ajodo.2017.08.007 | 2018 | this review only | not stated | not extracted yet |
| Miles 2018 Assessment of the rate of premolar extraction space closure in the maxillary arch with the AcceleDent Aura appliance vs no appliance in… PMID:29287658 | 2018 | this review only | not stated | not extracted yet |
| Mistry 2020 The effects of a clinically feasible application of low-level laser therapy on the rate of orthodontic tooth movement: A triple-blind,… PMID:32241351 | 2020 | this review only | Cumulative upper canine retraction from baseline (mm) | not extracted yet |
| Nahas 2017 Decrowding of lower anterior segment with and without photobiomodulation: a single center, randomized clinical trial DOI:10.1007/s10103-016-2094-5 | 2016 | this review only | not stated | not extracted yet |
| Nahas 2017 Decrowding of lower anterior segment with and without photobiomodulation: a single center, randomized clinical trial. PMID:27761668 | 2017 | this review only | not stated | not extracted yet |
| Pavlin 2015 Cyclic loading (vibration) accelerates tooth movement in orthodontic patients: A double-blind, randomized controlled trial DOI:10.1053/j.sodo.2015.06.005 | 2015 | this review only | Mean canine retraction rate (mm/month) | not extracted yet |
| Pereira 2014 matched by author and year (probable) | NR | this review only | Monthly upper canine retraction (mm); Cumulative upper canine retraction from baseline (mm); Monthly lower canine retraction (mm) | not extracted yet |
| Pérignon 2021 Effect of 970 nm low-level laser therapy on orthodontic tooth movement during Class II intermaxillary elastics treatment: a RCT DOI:10.1038/s41598-021-02610-7 | 2021 | this review only | not stated | not extracted yet |
| Pérignon 2021 Effect of 970 nm low-level laser therapy on orthodontic tooth movement during Class II intermaxillary elastics treatment: a RCT. PMID:34853360 | 2021 | this review only | not stated | not extracted yet |
| Qamruddin 2017 Effects of low-level laser irradiation on the rate of orthodontic tooth movement and associated pain with self-ligating brackets DOI:10.1016/j.ajodo.2017.03.023 | 2017 | this review only | not stated | not extracted yet |
| Reiss 2020 Biomarkers of orthodontic tooth movement with fixed appliances and vibration appliance therapy: a pilot study DOI:10.1093/ejo/cjaa026 | 2020 | this review only | not stated | not extracted yet |
| Reiss 2020 Biomarkers of orthodontic tooth movement with fixed appliances and vibration appliance therapy: a pilot study. PMID:32572439 | 2020 | this review only | not stated | not extracted yet |
| Samara 2018 Velocity of orthodontic active space closure with and without photobiomodulation therapy: a single-center, cluster randomized clinical trial DOI:10.1007/s41547-018-0026-3 | 2018 | this review only | not stated | not extracted yet |
| Sandoval 2017 Efficacy of Diode Laser Therapy in Acceleration of Orthodontic Space Closure: A Split-Mouth Randomized Clinical Trial DOI:10.16966/2378-7090.229 | 2017 | this review only | not stated | not extracted yet |
| Sandoval 2017 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Showkatbakhsh 2010 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Showkatbakhsh 2010 The effect of pulsed electromagnetic fields on the acceleration of tooth movement. PMID:21490989 | 2010 | this review only | Total upper canine retraction post-treatment (mm) | not extracted yet |
| Siriphan 2019 Effects of two frequencies of vibration on the maxillary canine distalization rate and <scp>RANKL</scp> and <scp>OPG</scp> secretion: A… DOI:10.1111/ocr.12301 | 2019 | this review only | not stated | not extracted yet |
| Siriphan 2019 Effects of two frequencies of vibration on the maxillary canine distalization rate and RANKL and OPG secretion: A randomized controlled… PMID:30758896 | 2019 | this review only | not stated | not extracted yet |
| Sousa 2011 Influence of Low-Level Laser on the Speed of Orthodontic Movement DOI:10.1089/pho.2009.2652 | 2011 | this review only | not stated | not extracted yet |
| Sousa 2011 Influence of low-level laser on the speed of orthodontic movement. PMID:21254890 | 2011 | this review only | Monthly upper canine retraction (mm); Cumulative upper canine retraction from baseline (mm); Total upper canine retraction post-treatment (mm) | not extracted yet |
| Taha 2020 Effects of mechanical vibrations on maxillary canine retraction and perceived pain: a pilot, single-center, randomized-controlled clinical… DOI:10.1007/s10266-019-00480-0 | 2020 | this review only | not stated | not extracted yet |
| Taha 2020 Effects of mechanical vibrations on maxillary canine retraction and perceived pain: a pilot, single-center, randomized-controlled clinical… PMID:31912371 | 2020 | this review only | Mean canine retraction rate (mm/month) | not extracted yet |
| Telatar 2021 Effectiveness of vibrational forces on orthodontic treatment DOI:10.1007/s00056-020-00257-z | 2020 | this review only | not stated | not extracted yet |
| Telatar 2021 Effectiveness of vibrational forces on orthodontic treatment : A randomized, controlled clinical trial. PMID:33125510 | 2021 | this review only | Mean canine retraction rate (mm/month) | not extracted yet |
| Üretürk 2017 The effect of low-level laser therapy on tooth movement during canine distalization. PMID:28289894 | 2017 | this review only | Cumulative upper canine retraction from baseline (mm) | not extracted yet |
| Varella 2018 Low-level laser therapy increases interleukin-1β in gingival crevicular fluid and enhances the rate of orthodontic tooth movement. PMID:30268264 | 2018 | this review only | Cumulative upper canine retraction from baseline (mm) | not extracted yet |
| Woodhouse 2015 Supplemental Vibrational Force During Orthodontic Alignment DOI:10.1177/0022034515576195 | 2015 | this review only | not stated | not extracted yet |
| Woodhouse 2015 Supplemental vibrational force during orthodontic alignment: a randomized trial. PMID:25758457 | 2015 | this review only | not stated | not extracted yet |
| Yassaei 2016 Effects of diode laser (980 nm) on orthodontic tooth movement and interleukin 6 levels in gingival crevicular fluid in female subjects DOI:10.1007/s10103-016-2045-1 | 2016 | this review only | not stated | not extracted yet |
| Yassaei 2016 Effects of diode laser (980 nm) on orthodontic tooth movement and interleukin 6 levels in gingival crevicular fluid in female subjects. PMID:27680969 | 2016 | this review only | Change in upper canine position (mm) | not extracted yet |
| Yildiz 2023 A different method to accelerate orthodontic tooth movement: Randomized controlled trial DOI:10.5937/bjdm2301051y | 2023 | this review only | Mean canine retraction rate (mm/month) | not extracted yet |
| Youssef 2008 The effect of low-level laser therapy during orthodontic movement: a preliminary study DOI:10.1007/s10103-007-0449-7 | 2007 | this review only | not stated | not extracted yet |
| Youssef 2008 The effect of low-level laser therapy during orthodontic movement: a preliminary study. PMID:17361391 | 2008 | this review only | Upper canine retraction rate (mm/month) | not extracted yet |
| Zheng 2021 Clinical research: low-level laser therapy in accelerating orthodontic tooth movement DOI:10.1186/s12903-021-01684-z | 2021 | this review only | not stated | not extracted yet |
| Zheng 2021 Clinical research: low-level laser therapy in accelerating orthodontic tooth movement. PMID:34182967 | 2021 | this review only | Cumulative upper canine retraction from baseline (mm) | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Healthy individuals of any age, gender or ethnicity undergoing orthodontic treatment | Orthodontic patients in 76 primary RCTs from 17 systematic reviews (leveling and alignment, canine retraction, en masse retraction, molar intrusion) |
| Intervention | Physical adjunctive interventions for accelerating orthodontic tooth movement (mechanical vibration, photobiomodulation, bioelectric stimulation) | Vibration devices (AcceleDent, customized appliances, powered toothbrush; 28 RCTs); photobiomodulation (LLLT and LED; 44 RCTs); bioelectric stimulation (BM, LIDEC, PEMF; 4 RCTs) |
| Comparison | Control groups receiving standard orthodontic treatment without adjunctive interventions | Standard orthodontic treatment without the adjunct |
| Outcomes | Rate of tooth displacement (e.g., mm/week/month) or equivalent efficacy metrics | Little irregularity index, orthodontic leveling and alignment time, canine retraction (rate, monthly, cumulative, total), en masse retraction rate, molar intrusion |
| Study designs | Systematic reviews/meta-analyses of RCTs (parallel or split-mouth designs) | RCTs (parallel and split-mouth), 76 primary studies published 2004 to 2024 |
| Timing | Not specified | Short-term follow-up; monthly time points up to 4 months, total post-treatment retraction |
AMSTAR 2 items
Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.
| Item | Extractor A | Extractor B | Agree |
|---|---|---|---|
| 1Research question includes PICO components | Yes | Yes | yes |
| 2Protocol established before the reviewcritical | Partial Yes | Partial Yes | yes |
| 3Choice of study designs explained | No | No | yes |
| 4Comprehensive literature searchcritical | Partial Yes | Partial Yes | yes |
| 5Study selection in duplicate | Yes | Yes | yes |
| 6Data extraction in duplicate | No | Yes | no |
| 7List of excluded studies with reasonscritical | Yes | Yes | yes |
| 8Included studies described in detail | Yes | Yes | yes |
| 9Risk of bias assessed satisfactorilycritical | RCT: Yes · NRSI: N/A | NRSI: N/A · RCT: Yes | no |
| 10Funding of included studies reported | No | No | yes |
| 11Appropriate meta-analysis methodscritical | RCT: No · NRSI: N/A | NRSI: N/A · RCT: Yes | no |
| 12Impact of risk of bias on the pooled results | No | No | yes |
| 13Risk of bias accounted for in interpretationcritical | Yes | Yes | yes |
| 14Heterogeneity explained | Yes | Yes | yes |
| 15Publication bias investigatedcritical | Yes | Yes | yes |
| 16Conflicts of interest reported | Yes | Yes | yes |
| Overall | Low | Moderate | no |