Primary study · included by 1 review

Effect of light-emitting diode-mediated photobiomodulation on extraction space closure in adolescents and young adults: A split-mouth, randomized controlled trial.

Al-Shafi 2021 · Al-Shafi Safa, Pandis Nikolaos, Darendeliler M Ali, et al. · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics · 2021

Included by

The Effectiveness of Physical Adjunctive Interventions in the Acceleration of Orthodontic Tooth Movement: An Umbrella Review and Meta-Analysis.

Non-Cochrane · intervention · 2026 · cited as Al-Shafi 2021 · References 36-111; Supporting Information Tables S4-S6

Outcome this study informs	Pooled effect	Evidence	Certainty
Monthly upper canine retraction (mm) Light-emitting diode (LED) therapy vs Standard orthodontic treatment without the adjunctive intervention · Month 3	MD -0.06 [-0.59, 0.46]	2 studies · 78 participants	Low
Monthly upper canine retraction (mm) Light-emitting diode (LED) therapy vs Standard orthodontic treatment without the adjunctive intervention · Month 2	MD 0.06 [-0.09, 0.21]	2 studies · 78 participants	Low
Monthly upper canine retraction (mm) Light-emitting diode (LED) therapy vs Standard orthodontic treatment without the adjunctive intervention · Month 1	MD 0.19 [-0.47, 0.86]	2 studies · 78 participants	Low

1 including review in total.