Search review questions

Periodontal disease prevalence · Adult residents of slums and non-slum urban settings of LMICs · Cross-sectional

Dental caries · Primary school children in Ethiopia

Parental concern / caregiver stress indices (parental perception and parenting stress about the child's oral health) · Parents/caregivers of children with disabilities (special needs; autism spectrum disorder or unspecified disability)… · Cross-sectional

Periodontitis (prevalence) · Adults · Adjusted OR

Dental caries in children · Children of mothers assessed for smoking status during pregnancy (early childhood dental caries) · Exposure during pregnancy; caries assessed in early childhood, Study region: USA

Dental caries prevalence (any DMFT), dichotomous · Brazilian children/adolescents in permanent dentition (BMI classified by CDC 2000 growth charts)

Effects of non-stevia high-intensity sweeteners (aspartame, sucralose, saccharin) on cariogenic bacteria in dental plaque or saliva · Generally healthy individuals across all age groups

Inter-examiner reliability · Children and adults with primary or permanent dentition · Overall

Spontaneous space closure · Children and adolescents with maxillary permanent first molar extraction · Follow-up to complete eruption of the permanent second molar, Maxilla

Dental caries (early childhood caries) · Narrative single study (Matee 1994): nocturnal breast-feeding

dmfs index score · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes,…

Dental caries (ECC) · Preschool children under 6 years of age · First dental examination before age 6 years, Cohort studies; sensitivity analysis excluding study 39

Change in Mutans streptococci (MS) count in saliva · Generally healthy individuals across all age groups (infants to elderly) · Post-consumption endpoint (varied durations across trials), Xylitol chewing gum vs no intervention/no gum (3 studies)

Dental caries (early childhood caries) · Preschool children (<6 years) · Cohort studies

Pulp exposure rate · Patients with deep carious lesions in permanent (mainly posterior) teeth · 1 to 5 years (follow-up varied by study)

Dental caries, prevalence · Primary school children in Ethiopia · Sampling technique: systematic random sampling

Mother microbiological presence (high-level mutans streptococci / lactobacilli) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6…

Dental caries / early childhood caries (ECC) · Children (approx. 4-18 years) · Region: Asian countries

Caries arrestment at the surface level · Children and adults without systemic diseases affecting dental health · 12 months to 18 months

Intra-examiner reliability · Children and adults with primary or permanent dentition undergoing dental caries assessment · Cross-sectional diagnostic accuracy (index test vs reference standard, in-vivo), Overall (studies reporting intra-examiner reliability; narrative synthesis)

Caries presence in primary teeth · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6… · Children assessed at 4 yrs

Dental service utilization · Adults in LMIC urban and slum settings

Dental caries (prevalence) · Adults · Non-standard periodontitis definition

Early childhood caries (ECC) · Children aged <6 years · Study location: America/Canada/Brazil

Mother microbiological presence · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6…

Dental caries · Children (<18 years) with vs without dental caries · Recessive model (TT vs TC+CC), PCR-RFLP genotyping

Incidence of new ICLs (mean number of new lesions per subject) · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new… · During fixed orthodontic treatment (development of new lesions), Overall (random-effects model)

White spot lesion incidence, area, and depth · Patients undergoing fixed orthodontic treatment · 2 and 4 months after treatment start

Caries presence in top front four teeth · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes,… · Children assessed at 3 yrs, Higher-protein diet trial

Prevalence of ICLs (mean number of lesions per subject) · Patients (permanent dentition) during or after fixed orthodontic treatment with fixed (multibracket) appliances · During or after fixed orthodontic treatment (cross-sectional/at debonding), Overall (random-effects model)

Dental caries in children · Children of mothers assessed for smoking status during pregnancy (early childhood dental caries) · Exposure during pregnancy; caries assessed in early childhood, Dental examination: Clinical and radiographic examinations

Dental caries (proportion of patients with caries) · Children and adolescents aged 0-18 years with non-syndromic cleft lip and palate (CLP)

Periodontopathogenic microbiota composition · Narrative: Campylobacter/Fusobacterium/F. nucleatum/Prevotella intermedia-nigrescens/Parvimonas micra/Porphyromonas gingivalis in CLP

Secondary prevention of caries · Children and adults (with or without carious lesions)

Lactobacillus spp. salivary/plaque counts (cariogenic microbiota) · Children and adolescents aged 0-18 years with non-syndromic cleft lip and palate (CLP)

Overall success (composite of clinical and radiographic success) · Mature teeth, irreversible pulpitis

Dental caries (prevalence) · Adults · Adjusted OR

Fluoride ion release · Human enamel specimens around orthodontic brackets (in vitro) · up to 6 months, Overall

Dental caries · Children (<18 years) with vs without dental caries · Dominant model (TT+TC vs CC), Caucasian ethnicity

Bacterial growth inhibition (MIC/MBC) · Streptococcus mutans (in vitro cultures and biofilms)

Dental caries (prevalence) · Children (<18 years) with intellectual and developmental disabilities (IDD) in India · Overall

Dental caries prevalence · Children aged 2 to 8 years · Maternal pregnancy to child age 2 to 8 years, Children of mothers with low prenatal vitamin D

Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years · Fluorosis assessed when most permanent teeth of interest had erupted (6 to 18 years)

Early childhood caries (ECC) · Children aged <6 years · Study design: Cross-sectional

dmfs index score (decayed, missing, filled primary surfaces; range 0-80) · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes,… · Children assessed at 1-3 yrs

Periodontal disease (prevalence) · Children (<18 years) with intellectual and developmental disabilities (IDD) in India

Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Time period: before 2017

Bacterial cell death · Streptococcus mutans cultures and biofilms

Serum vitamin D (25(OH)D): ECC vs caries-free · Case-control studies (Fig 3)

White spot lesion area · Patients undergoing fixed orthodontic treatment · During orthodontic treatment