Cochrane Review Group
Acute Respiratory Infections
109 systematic reviews in Acute Respiratory Infections ask 1,080 questions. 12.2% have no studies to answer them, 15.6% rest on very low certainty evidence and 35.5% reach moderate or high certainty.
Reviews
109
Questions
1,080
current versions
No studies
12.2%
Moderate or high
35.5%
No studies 132 · 12.2%Ungraded 90 · 8.3%Very low 169 · 15.6%Low 306 · 28.3%Moderate 287 · 26.6%High 96 · 8.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Thinnest evidence
All no studies and very low questions| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Zinc vs placebo Risk of serious adverse events, including those that may be complications of the common cold · adults and children with colds and/or upper respiratory infections Zinc for prevention and treatment of the common cold (2024) · Cochrane | no estimate extracted | NR | No studies |
Zinc vs placebo Risk of adverse events, including those that may be due to zinc supplements Duration of · adults and children without colds Zinc for prevention and treatment of the common cold (2024) · Cochrane | no estimate extracted | 7 studies · 1517 participants | Very low |
Zinc vs placebo Risk of continuing colds at study end Duration of · adults and children with colds and/or upper respiratory infections Zinc for prevention and treatment of the common cold (2024) · Cochrane | no estimate extracted | 5 studies · 357 participants | Very low |
Zinc vs placebo Standardised mean global symptom severity Duration of · adults and children with colds and/or upper respiratory infections Zinc for prevention and treatment of the common cold (2024) · Cochrane | no estimate extracted | 2 studies · 261 participants | Very low |
Summary of findings table ‐ Vitamin A supplements vs placebo Adverse events · children up to the age of 7 at risk of upper respiratory tract infection Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years… (2024) · Cochrane | no estimate extracted | 1 study · 116 participants | Very low |
Summary of findings table ‐ Vitamin A supplements vs placebo Severity of subjective symptoms (mean duration of acute URTI) · children up to the age of 7 at risk of upper respiratory tract infection Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years… (2024) · Cochrane | no estimate extracted | 2 studies · 290 participants | Very low |
Summary of findings table ‐ Vitamin A supplements vs placebo Time to occurrence of acute URTI ‐ not reported · children up to the age of 7 at risk of upper respiratory tract infection Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years… (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Vitamin A supplements vs placebo Number of cases with complications ‐ not reported · children up to the age of 7 at risk of upper respiratory tract infection Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years… (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Vitamin A supplements vs placebo Rate of hospitalisation ‐ not reported · children up to the age of 7 at risk of upper respiratory tract infection Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years… (2024) · Cochrane | no estimate extracted | NR | No studies |
Any glucocorticoid vs placebo Change in croup score. · children with croup Glucocorticoids for croup in children (2023) · Cochrane | no estimate extracted | 8 studies · 351 participants | Very low |
Any glucocorticoid vs epinephrine Change in croup score. · children with croup Glucocorticoids for croup in children (2023) · Cochrane | no estimate extracted | 2 studies · 130 participants | Very low |
Any glucocorticoid vs epinephrine Change in croup score. · children with croup Glucocorticoids for croup in children (2023) · Cochrane | no estimate extracted | 2 studies · 63 participants | Very low |
Reviews 109
Heliox for croup in children
CochraneSoF table
18 questions
Antibiotic therapy versus no antibiotic therapy for children aged 2 to 59 months with WHO‐defined non‐severe pneumonia and wheeze
CochraneSoF table
4 questions
Vitamin C supplementation for prevention and treatment of pneumonia
CochraneSoF table
8 questions
Non‐corticosteroid adjuvant therapies for acute bacterial meningitis
CochraneSoF table
7 questions
Parenteral versus enteral fluid therapy for children hospitalised with bronchiolitis
CochraneSoF table
7 questions
Palivizumab for preventing severe respiratory syncytial virus (RSV) infection in children
CochraneSoF table
6 questions
Antibiotics for hospital‐acquired pneumonia in neonates and children
CochraneSoF table
12 questions
Pneumococcal conjugate vaccines for preventing acute otitis media in children
CochraneSoF table
7 questions
Corticosteroids as standalone or add‐on treatment for sore throat
CochraneSoF table
8 questions
Exercise versus no exercise for the occurrence, severity, and duration of acute respiratory infections
CochraneSoF table
5 questions
Efficacy and safety of rapid tests to guide antibiotic prescriptions for sore throat
CochraneSoF table
4 questions
Diagnostic test accuracy of jolt accentuation for headache in acute meningitis in the emergency setting
CochraneSoF table
12 questions
Magnesium sulphate for treating acute bronchiolitis in children up to two years of age
CochraneSoF table
28 questions
Chest physiotherapy for pneumonia in children
CochraneSoF table
4 questions
Corticosteroids as adjunctive therapy in the treatment of influenza
CochraneSoF table
4 questions
Adverse events in people taking macrolide antibiotics versus placebo for any indication
CochraneSoF table
10 questions
Probiotics for preventing acute otitis media in children
CochraneSoF table
8 questions
Vaccines for preventing influenza in healthy adults
CochraneSoF table
6 questions
Vaccines for preventing influenza in the elderly
CochraneSoF table
7 questions
Vaccines for preventing influenza in healthy children
CochraneSoF table
16 questions
Interventions to increase influenza vaccination rates of those 60 years and older in the community
CochraneSoF table
29 questions
Antibiotics for acute rhinosinusitis in adults
CochraneSoF table
7 questions
Honey for acute cough in children
CochraneSoF table
59 questions
Osmotic therapies added to antibiotics for acute bacterial meningitis
CochraneSoF table
6 questions
Cyclamen europaeum extract for acute sinusitis
CochraneSoF table
2 questions