Cochrane · systematic review · CD001955
Glucocorticoids for croup in children
Aregbesola, A, Tam, CM, Kothari, A, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
12
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 25%Low 9 · 75%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsAny glucocorticoid compared to placebo for croup
Population: children with croup
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in croup score. Any glucocorticoid vs placebo | no estimate extracted | 7 studies · 426 participants | Low Downgraded: risk of bias, inconsistency |
Change in croup score. Any glucocorticoid vs placebo | no estimate extracted | 11 studies · 959 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Change in croup score. Any glucocorticoid vs placebo | no estimate extracted | 8 studies · 571 participants | Low Downgraded: risk of bias, inconsistency |
Change in croup score. Any glucocorticoid vs placebo | no estimate extracted | 8 studies · 351 participants | Very low Downgraded: risk of bias, inconsistency |
Return visits or (re)admissions or both Any glucocorticoid vs placebo | RR 0.52 [0.36, 0.75] | 10 studies · 1679 participants | Low Downgraded: risk of bias, inconsistency |
Adverse events Any glucocorticoid vs placebo | no estimate extracted | 13 studies · 1399 participants | Low Downgraded: risk of bias, imprecision |
Any glucocorticoid compared to epinephrine for croup
Population: children with croup
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in croup score. Any glucocorticoid vs epinephrine | no estimate extracted | 2 studies · 130 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Change in croup score. Any glucocorticoid vs epinephrine | no estimate extracted | 2 studies · 63 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Change in croup score. Any glucocorticoid vs epinephrine | no estimate extracted | 3 studies · 129 participants | Low Downgraded: risk of bias, imprecision |
Change in croup score. Any glucocorticoid vs epinephrine | no estimate extracted | 3 studies · 129 participants | Low Downgraded: risk of bias, imprecision |
Return visits or (re)admissions or both Any glucocorticoid vs epinephrine | RD 0 | 2 studies · 130 participants | Low Downgraded: risk of bias, imprecision |
Adverse events Any glucocorticoid vs epinephrine | no estimate extracted | 3 studies · 162 participants | Low Downgraded: risk of bias, imprecision |