Search review questions

Participant acceptance/satisfaction · Dental patients undergoing restorative treatment (no age or gender restriction) · Pit and fissure sealing (permanent molars)

Overall survival, induction platinum + 5-fluorouracil prior to radiotherapy vs radiotherapy alone · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 36 months

Childhood dental caries · Children in cross-sectional studies · Poland, United States, Sweden, Italy, and Japan, Sensitivity: excluded Julihn et al. 2009

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Case-control studies of children and adults (China, India, Czech Republic, Turkey), Ethnicity: Caucasian

Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or… · 1 week after completion of expansion

Secondary caries · People with permanent or adult posterior teeth requiring restoration (parallel-group trials involved children aged 6… · Follow-up >= 3 years, Split-mouth trials

All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report, Crude

Gingival index (GI) · Adults undergoing orthodontic treatment · 6 to 12 weeks, Adults

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Caries detection level

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Case-control studies of children and adults (China, India, Czech Republic, Turkey), Ethnicity: Asian

Incidence of eruption of the PDC into the mouth · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC) · 18 months (mean; mITT)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro

Number of decayed teeth · Adults (general and hospital populations assessed in case-control studies) · Hospital/clinic-based case-control studies from Asia, America and Europe

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Caries detection level

Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months

Molar expansion (maxillary intermolar width) · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or…

Mean DMFT · School children aged 11-17 years in Sharjah · Overall

Diagnostic accuracy for proximal caries detection (1/3 dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, 1/3 dentin detection level

Molar-incisor hypomineralization prevalence · School children aged 8-12 years in Dubai public schools · Females

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Digital

Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances · 12-24 months follow-up, Patients undergoing fixed (multibracket) orthodontic appliance treatment; clinical/dental setting; analysis at tooth level

Childhood dental caries · Children in cross-sectional studies · Poland, United States, Sweden, Italy, and Japan, Sensitivity: excluded Majorana et al. 2014

Harms (pain) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth · first days

Canine expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or… · 3 months after completion of expansion

Radiographic proximal caries lesion progression · Patients with non-cavitated proximal caries lesions · Longest available follow-up

Change in diastolic blood pressure (DBP, mmHg) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension · Short term (follow-up 2-3 months), People diagnosed with periodontitis

Canine expansion (inter-canine distance) · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or…

Specificity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies)

Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or…

Dental caries prevalence · General population in Ethiopia (all ages, age range 6-100 years) · Community-, school-, and hospital/clinic-based populations across regions of Ethiopia, Others (Oromia, Harar town, SNNPR)

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Dentine-caries (D3) prevalence high >=35% or unreported (non-CBCT)

Sensitivity · Children, adolescents, or adults presenting asymptomatically or suspected of early enamel caries (in vivo), or… · Up to 3 months between index test and reference standard (in vivo studies)

Water samples with fluoride concentration above the acceptable range · Region: South Brazil

Disease-free survival, induction platinum + 5-fluorouracil prior to radiotherapy vs radiotherapy alone · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

Dental caries prevalence · Rwanda

Amount of crowding (Little's Irregularity Index) at 12 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth · 12 weeks

Plasma level of IL-6 (pg/mL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension · Short term, People diagnosed with periodontitis and hypertension

Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces · in vivo

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Caries detection level

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Proximal surfaces (non-CBCT)

Specificity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Occlusal surface

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces · in vivo

Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces · in vivo

Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces · in vivo

Canine expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or… · 12 weeks after start of treatment

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Caries detection level

Prevalence of early childhood caries (primary dentition) · Toddlers and preschool children, 2 to 6 years of age (primary dentition) · Caries assessed at 8 months to 6 years of age, Community/population-based; studies from Europe, Asia, South America and Israel