Non-Cochrane · DTA · PM34128130
Systematic review and meta-analysis of diagnostic methods for occlusal surface caries.
Kapor Svetlana, Rankovic Mila Janjic, Khazaei Yegane, et al. · Clinical oral investigations · 2021 · PubMed · doi:10.1007/s00784-021-04024-1
Full textEvery question was extracted from the full text, figures and supplements by two independent LLM extractors, disagreements adjudicated. Rows cite where in the review the value comes from.
Questions
85
current version
GRADE rated
0
No studies
1
Included studies
73
linked below
No studies 1 · 1.2%Ungraded 84 · 98.8%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Human permanent posterior teeth (premolars and molars); primary caries on occlusal (pit-and-fissure) surfaces; in vitro (extracted teeth) and in vivo (patients, any age) | 37 studies of human permanent posterior teeth (29 in vitro, 8 in vivo) |
| Intervention | Index tests: visual examination (VE); conventional bitewing radiography (D/E/F-speed); digital bitewing radiography (sensor/phosphor plate); laser fluorescence (DIAGNOdent 2095 and 2190/Pen); fibre-optic transillumination (FOTI); quantitative light-induced fluorescence (QLF) | Pooled estimates reported for VE, conventional BWR (D/E/F-speed), digital BWR (phosphor plates), LF 2095, LF pen 2190, and FOTI; no eligible QLF studies; no pooled in vivo digital BWR or FOTI |
| Comparison | Reference standard: histological validation (in vitro); cavity preparation or biopsy (in vivo) | Histological validation (in vitro); cavity preparation or biopsy (in vivo) |
| Outcomes | Diagnostic accuracy (sensitivity, specificity, diagnostic odds ratio, sROC AUC) and/or reliability at three thresholds: caries detection level (D0 vs D1-D4), dentin detection level (D0-2 vs D3-4), 1/3 dentin detection level (Ekstrand) | Pooled sensitivity, specificity, sROC AUC, and DOR by index test x threshold (Tables 3 [in vitro] and 4 [in vivo]); in vitro SP ranged 0.50 to 0.97; highest AUC 0.89 (VE, 1/3 dentin, in vitro) |
| Study designs | In vitro and in vivo diagnostic accuracy studies with a valid reference standard | In vitro (29 studies); in vivo (8 studies) |
| Timing | Not specified | Not specified |
Search date: 31 December 2018. Databases: MEDLINE (via PubMed); EMBASE (via Ovid); hand-searching of reference lists of included studies and reviews
Questions and results
Visual examination (VE) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)
Population: Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, visual examination pooled sensitivity was 0.46 (95% CI 0.20 to 0.73) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.46 [0.20, 0.73] | 8 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, visual examination pooled specificity was 0.87 (95% CI 0.72 to 0.95) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.87 [0.72, 0.95] | 8 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, visual examination pooled summary ROC AUC was 0.59 for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.59 | 3 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, visual examination pooled diagnostic odds ratio was 5.93 (95% CI 3.11 to 11.31) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 5.93 [3.11, 11.31] | 8 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, visual examination pooled specificity was 0.83 (95% CI 0.70 to 0.92) for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.83 [0.70, 0.92] | 3 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) In in vitro, visual examination pooled diagnostic odds ratio was 16.6 (95% CI 4.85 to 56.79) for occlusal caries at the 1/3 dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 16.6 [4.85, 56.79] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, visual examination pooled summary ROC AUC was 0.79 for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.79 | 8 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, visual examination pooled diagnostic odds ratio was 5.55 (95% CI 1.88 to 16.38) for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 5.55 [1.88, 16.38] | 3 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) In in vitro, visual examination pooled specificity was 0.88 (95% CI 0.83 to 0.92) for occlusal caries at the 1/3 dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.88 [0.83, 0.92] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, visual examination pooled sensitivity was 0.59 (95% CI 0.52 to 0.67) for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.59 [0.52, 0.67] | 3 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) In in vitro, visual examination pooled sensitivity was 0.69 (95% CI 0.51 to 0.82) for occlusal caries at the 1/3 dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.69 [0.51, 0.82] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) In in vitro, visual examination pooled summary ROC AUC was 0.89 for occlusal caries at the 1/3 dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.89 | 2 studies | Ungraded |
Conventional bitewing radiography (D-speed film) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)
Population: Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, conventional bitewing radiography (D-speed) pooled specificity was 0.73 (95% CI 0.53 to 0.87) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.73 [0.53, 0.87] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, conventional bitewing radiography (D-speed) pooled diagnostic odds ratio was 1.94 (95% CI 0.46 to 8.17) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 1.94 [0.46, 8.17] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, conventional bitewing radiography (D-speed) pooled sensitivity was 0.42 (95% CI 0.18 to 0.69) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.42 [0.18, 0.69] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, conventional bitewing radiography (D-speed) pooled summary ROC AUC was 0.60 for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.60 | 1 study | Ungraded |
Conventional bitewing radiography (E-speed film) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)
Population: Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, conventional bitewing radiography (E-speed) pooled diagnostic odds ratio was 10.69 (95% CI 3.67 to 31.15) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 10.69 [3.67, 31.15] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, conventional bitewing radiography (E-speed) pooled sensitivity was 0.48 (95% CI 0.21 to 0.77) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.48 [0.21, 0.77] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, conventional bitewing radiography (E-speed) pooled summary ROC AUC was 0.75 for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.75 | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, conventional bitewing radiography (E-speed) pooled specificity was 0.95 (95% CI 0.53 to 0.997) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.95 [0.53, 0.997] | 2 studies | Ungraded |
Conventional bitewing radiography (F-speed film) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)
Population: Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, conventional bitewing radiography (F-speed) pooled specificity was 0.97 (95% CI 0.71 to 0.998) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.97 [0.71, 0.998] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, conventional bitewing radiography (F-speed) pooled diagnostic odds ratio was 23.60 (95% CI 8.28 to 67.24) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 23.60 [8.28, 67.24] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, conventional bitewing radiography (F-speed) pooled summary ROC AUC was 0.82 for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.82 | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, conventional bitewing radiography (F-speed) pooled sensitivity was 0.50 (95% CI 0.22 to 0.79) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.50 [0.22, 0.79] | 2 studies | Ungraded |
Digital bitewing radiography (phosphor plates) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)
Population: Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, digital bitewing radiography (phosphor plates) pooled summary ROC AUC was 0.73 for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.73 | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, digital bitewing radiography (phosphor plates) pooled specificity was 0.95 (95% CI 0.59 to 0.995) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.95 [0.59, 0.995] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, digital bitewing radiography (phosphor plates) pooled sensitivity was 0.48 (95% CI 0.24 to 0.73) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.48 [0.24, 0.73] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, digital bitewing radiography (phosphor plates) pooled diagnostic odds ratio was 15.57 (95% CI 0.47 to 515.27) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 15.57 [0.47, 515.27] | 2 studies | Ungraded |
Laser fluorescence (DIAGNOdent 2095) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)
Population: Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, laser fluorescence (DIAGNOdent 2095) pooled summary ROC AUC was 0.81 for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.81 | 6 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, laser fluorescence (DIAGNOdent 2095) pooled summary ROC AUC was 0.79 for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.79 | 7 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, laser fluorescence (DIAGNOdent 2095) pooled specificity was 0.78 (95% CI 0.68 to 0.85) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.78 [0.68, 0.85] | 7 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, laser fluorescence (DIAGNOdent 2095) pooled sensitivity was 0.75 (95% CI 0.58 to 0.86) for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.75 [0.58, 0.86] | 6 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, laser fluorescence (DIAGNOdent 2095) pooled specificity was 0.76 (95% CI 0.60 to 0.87) for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.76 [0.60, 0.87] | 6 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, laser fluorescence (DIAGNOdent 2095) pooled sensitivity was 0.68 (95% CI 0.54 to 0.79) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.68 [0.54, 0.79] | 7 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, laser fluorescence (DIAGNOdent 2095) pooled diagnostic odds ratio was 8.01 (95% CI 4.04 to 15.88) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 8.01 [4.04, 15.88] | 7 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, laser fluorescence (DIAGNOdent 2095) pooled diagnostic odds ratio was 10.28 (95% CI 4.35 to 24.28) for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 10.28 [4.35, 24.28] | 6 studies | Ungraded |
Laser fluorescence pen (DIAGNOdent 2190/Pen) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)
Population: Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, laser fluorescence pen (2190) pooled diagnostic odds ratio was 11.83 (95% CI 2.66 to 52.63) for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 11.83 [2.66, 52.63] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, laser fluorescence pen (2190) pooled summary ROC AUC was 0.78 for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.78 | 4 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, laser fluorescence pen (2190) pooled specificity was 0.77 (95% CI 0.62 to 0.88) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.77 [0.62, 0.88] | 4 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, laser fluorescence pen (2190) pooled sensitivity was 0.63 (95% CI 0.37 to 0.83) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.63 [0.37, 0.83] | 4 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, laser fluorescence pen (2190) pooled sensitivity was 0.78 (95% CI 0.44 to 0.94) for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.78 [0.44, 0.94] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, laser fluorescence pen (2190) pooled diagnostic odds ratio was 5.85 (95% CI 1.77 to 19.30) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 5.85 [1.77, 19.30] | 4 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, laser fluorescence pen (2190) pooled summary ROC AUC was 0.77 for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.77 | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, laser fluorescence pen (2190) pooled specificity was 0.77 (95% CI 0.62 to 0.87) for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.77 [0.62, 0.87] | 2 studies | Ungraded |
Fibre-optic transillumination (FOTI) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)
Population: Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, fibre-optic transillumination pooled summary ROC AUC was 0.92 for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.92 | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, fibre-optic transillumination pooled sensitivity was 0.97 (95% CI -0.92 to 0.99) for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.97 [-0.92, 0.99] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, fibre-optic transillumination pooled specificity was 0.97 (95% CI 0.89 to 0.994) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.97 [0.89, 0.994] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, fibre-optic transillumination pooled diagnostic odds ratio was 37.77 (95% CI 13.69 to 104.19) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 37.77 [13.69, 104.19] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, fibre-optic transillumination pooled summary ROC AUC was 0.92 for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | AUC 0.92 | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, fibre-optic transillumination pooled diagnostic odds ratio was 38.33 (95% CI 10.15 to 144.77) for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | DOR 38.33 [10.15, 144.77] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vitro, fibre-optic transillumination pooled specificity was 0.50 (95% CI 0.34 to 0.66) for occlusal caries at the caries detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Specificity 0.50 [0.34, 0.66] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vitro, fibre-optic transillumination pooled sensitivity was 0.49 (95% CI 0.20 to 0.79) for occlusal caries at the dentin detection level; ungraded. Source: Table 3 (bivariate meta-analysis, in vitro studies) · same question in other reviews | Sensitivity 0.49 [0.20, 0.79] | 2 studies | Ungraded |
Visual examination (VE) vs Cavity preparation or biopsy (operative validation)
Population: Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) In in vivo, visual examination pooled specificity was 0.77 (95% CI 0.67 to 0.85) for occlusal caries at the 1/3 dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Specificity 0.77 [0.67, 0.85] | 3 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, visual examination pooled specificity was 0.47 (95% CI 0.26 to 0.70) for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Specificity 0.47 [0.26, 0.70] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, visual examination pooled summary ROC AUC was 0.70 for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | AUC 0.70 | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) In in vivo, visual examination pooled sensitivity was 0.72 (95% CI 0.52 to 0.86) for occlusal caries at the 1/3 dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Sensitivity 0.72 [0.52, 0.86] | 3 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) In in vivo, visual examination pooled diagnostic odds ratio was 10.18 (95% CI 3.94 to 26.29) for occlusal caries at the 1/3 dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | DOR 10.18 [3.94, 26.29] | 3 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, visual examination pooled sensitivity was 0.70 (95% CI 0.59 to 0.80) for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Sensitivity 0.70 [0.59, 0.80] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) In in vivo, visual examination pooled summary ROC AUC was 0.77 for occlusal caries at the 1/3 dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | AUC 0.77 | 3 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, visual examination pooled diagnostic odds ratio was 2.14 (95% CI 0.73 to 6.28) for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | DOR 2.14 [0.73, 6.28] | 2 studies | Ungraded |
Conventional bitewing radiography (D-speed film) vs Cavity preparation or biopsy (operative validation)
Population: Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, conventional bitewing radiography (D-speed) pooled sensitivity was 0.65 (95% CI 0.57 to 0.73) for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Sensitivity 0.65 [0.57, 0.73] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vivo, conventional bitewing radiography (D-speed) pooled specificity was 0.75 (95% CI 0.68 to 0.82) for occlusal caries at the dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Specificity 0.75 [0.68, 0.82] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, conventional bitewing radiography (D-speed) pooled summary ROC AUC was 0.65 for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | AUC 0.65 | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vivo, conventional bitewing radiography (D-speed) pooled sensitivity was 0.79 (95% CI 0.41 to 0.96) for occlusal caries at the dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Sensitivity 0.79 [0.41, 0.96] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, conventional bitewing radiography (D-speed) pooled specificity was 0.58 (95% CI 0.42 to 0.72) for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Specificity 0.58 [0.42, 0.72] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vivo, conventional bitewing radiography (D-speed) pooled summary ROC AUC was 0.77 for occlusal caries at the dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | AUC 0.77 | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vivo, conventional bitewing radiography (D-speed) pooled diagnostic odds ratio was 11.79 (95% CI 2.43 to 57.24) for occlusal caries at the dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | DOR 11.79 [2.43, 57.24] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, conventional bitewing radiography (D-speed) pooled diagnostic odds ratio was 2.59 (95% CI 1.24 to 5.44) for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | DOR 2.59 [1.24, 5.44] | 1 study | Ungraded |
Conventional bitewing radiography (E-speed film) vs Cavity preparation or biopsy (operative validation)
Population: Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vivo, conventional bitewing radiography (E-speed) pooled diagnostic odds ratio was 127.56 (95% CI 7.38 to 2203.70) for occlusal caries at the dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | DOR 127.56 [7.38, 2203.70] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, conventional bitewing radiography (E-speed) pooled summary ROC AUC was 0.94 for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | AUC 0.94 | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, conventional bitewing radiography (E-speed) pooled sensitivity was 0.80 (95% CI 0.71 to 0.87) for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Sensitivity 0.80 [0.71, 0.87] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, conventional bitewing radiography (E-speed) pooled diagnostic odds ratio was 60.37 (95% CI 3.31 to 1100.70) for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | DOR 60.37 [3.31, 1100.70] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, conventional bitewing radiography (E-speed) pooled specificity was 0.94 (95% CI 0.46 to 0.996) for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Specificity 0.94 [0.46, 0.996] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vivo, conventional bitewing radiography (E-speed) pooled specificity was 0.98 (95% CI 0.79 to 0.998) for occlusal caries at the dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Specificity 0.98 [0.79, 0.998] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vivo, conventional bitewing radiography (E-speed) pooled summary ROC AUC was 0.90 for occlusal caries at the dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | AUC 0.90 | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vivo, conventional bitewing radiography (E-speed) pooled sensitivity was 0.76 (95% CI 0.61 to 0.87) for occlusal caries at the dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Sensitivity 0.76 [0.61, 0.87] | 2 studies | Ungraded |
Laser fluorescence (DIAGNOdent 2095) vs Cavity preparation or biopsy (operative validation)
Population: Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, laser fluorescence (DIAGNOdent 2095) pooled diagnostic odds ratio was 18.33 (95% CI 7.57 to 44.37) for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | DOR 18.33 [7.57, 44.37] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vivo, laser fluorescence (DIAGNOdent 2095) pooled summary ROC AUC was 0.92 for occlusal caries at the dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | AUC 0.92 | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, laser fluorescence (DIAGNOdent 2095) pooled sensitivity was 0.88 (95% CI 0.81 to 0.93) for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Sensitivity 0.88 [0.81, 0.93] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vivo, laser fluorescence (DIAGNOdent 2095) pooled diagnostic odds ratio was 35.90 (95% CI 13.43 to 96.00) for occlusal caries at the dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | DOR 35.90 [13.43, 96.00] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, laser fluorescence (DIAGNOdent 2095) pooled specificity was 0.71 (95% CI 0.55 to 0.83) for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Specificity 0.71 [0.55, 0.83] | 1 study | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vivo, laser fluorescence (DIAGNOdent 2095) pooled specificity was 0.78 (95% CI 0.46 to 0.94) for occlusal caries at the dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Specificity 0.78 [0.46, 0.94] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) In in vivo, laser fluorescence (DIAGNOdent 2095) pooled sensitivity was 0.91 (95% CI 0.86 to 0.95) for occlusal caries at the dentin detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | Sensitivity 0.91 [0.86, 0.95] | 2 studies | Ungraded |
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) In in vivo, laser fluorescence (DIAGNOdent 2095) pooled summary ROC AUC was 0.88 for occlusal caries at the caries detection level; ungraded. Source: Table 4 (bivariate meta-analysis, in vivo studies) · same question in other reviews | AUC 0.88 | 1 study | Ungraded |
Quantitative light-induced fluorescence (QLF) vs Histological validation (in vitro) or cavity preparation/biopsy (in vivo)
Population: Human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Diagnostic accuracy for occlusal caries detection (any threshold) No eligible QLF studies met the meta-analysis inclusion criteria (candidate QLF studies were identified but none had acceptable index/reference tests and reporting quality). Source: Results ('none used QLF'); Table 2 (QLF: 0 studies with acceptable index/reference test) · same question in other reviews | no estimate extracted | 0 studies | No studies |
Included primary studies 73
Open as a trial list| Study | Also included by | Outcomes it informs here | Trial PICO | Results |
|---|---|---|---|---|
| Akarsu 2006 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Akarsu 2006 In vivo comparison of the efficacy of DIAGNOdent by visual inspection and radiographic diagnostic techniques in the diagnosis of occlusal… PMID:17022365 | this review only | not stated | not extracted yet | not extracted yet |
| Aktan 2012 A novel LED-based device for occlusal caries detection DOI:10.1007/s10103-011-1020-0 | this review only | not stated | not extracted yet | not extracted yet |
| Aktan 2012 A novel LED-based device for occlusal caries detection. PMID:22080431 | this review only | not stated | not extracted yet | not extracted yet |
| Angnes 2005 Occlusal caries diagnosis in permanent teeth: an in vitro study DOI:10.1590/s1806-83242005000400002 | this review only | not stated | not extracted yet | not extracted yet |
| Angnes 2005 Occlusal caries diagnosis in permanent teeth: an in vitro study. PMID:16491250 | this review only | not stated | not extracted yet | not extracted yet |
| Bahrololoomi 2015 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Bahrololoomi 2015 Comparison of Radiography, Laser Fluorescence and Visual Examination for Diagnosing Incipient Occlusal Caries of Permanent First Molars. PMID:26877727 | this review only | not stated | not extracted yet | not extracted yet |
| Baseren 2003 Validity of a laser fluorescence system (DIAGNOdent) for detection of occlusal caries in third molars: an <i>in vitro</i> study DOI:10.1111/j.1365-2842.2003.01164.x | this review only | not stated | not extracted yet | not extracted yet |
| Baseren 2003 Validity of a laser fluorescence system (DIAGNOdent) for detection of occlusal caries in third molars: an in vitro study. PMID:14641662 | this review only | not stated | not extracted yet | not extracted yet |
| Bozdemir 2013 <i>In Vivo</i> Performance of Two Devices for Occlusal Caries Detection DOI:10.1089/pho.2012.3458 | this review only | not stated | not extracted yet | not extracted yet |
| Bozdemir 2013 In vivo performance of two devices for occlusal caries detection. PMID:23763480 | this review only | not stated | not extracted yet | not extracted yet |
| Bucher 2015 Occlusal Caries Extension in Relation to Visual and Radiographic Diagnostic Criteria: Results from a Microcomputed Tomography Study DOI:10.2341/13-128-l | this review only | not stated | not extracted yet | not extracted yet |
| Bucher 2015 Occlusal caries extension in relation to visual and radiographic diagnostic criteria: results from a microcomputed tomography study. PMID:25695643 | this review only | not stated | not extracted yet | not extracted yet |
| Castilho 2016 Validation of <scp>DIAGNO</scp>dent laser fluorescence and the International Caries Detection and Assessment System (<scp>ICDAS</scp>) in… DOI:10.1111/eos.12257 | this review only | not stated | not extracted yet | not extracted yet |
| Castilho 2016 Validation of DIAGNOdent laser fluorescence and the International Caries Detection and Assessment System (ICDAS) in diagnosis of occlusal… PMID:26917102 | this review only | not stated | not extracted yet | not extracted yet |
| Cortes 2000 An in vitro Comparison of the Ability of Fibre–Optic Transillumination, Visual Inspection and Radiographs to Detect Occlusal Caries and… DOI:10.1159/000016621 | this review only | not stated | not extracted yet | not extracted yet |
| Cortes 2000 An in vitro comparison of the ability of fibre-optic transillumination, visual inspection and radiographs to detect occlusal caries and… PMID:11093016 | this review only | not stated | not extracted yet | not extracted yet |
| Cortes 2003 An in vitro Comparison of a Combined FOTI/Visual Examination of Occlusal Caries with Other Caries Diagnostic Methods and the Effect of… DOI:10.1159/000068230 | this review only | not stated | not extracted yet | not extracted yet |
| Cortes 2003 An in vitro comparison of a combined FOTI/visual examination of occlusal caries with other caries diagnostic methods and the effect of… PMID:12566633 | this review only | not stated | not extracted yet | not extracted yet |
| Cotta 2015 Lesion Activity Assessment (LAA) in Conjunction With International Caries Detection and Assessment System (ICDAS) for Occlusal Caries… DOI:10.2341/13-332-c | this review only | not stated | not extracted yet | not extracted yet |
| Cotta 2015 Lesion Activity Assessment (LAA) in Conjunction With International Caries Detection and Assessment System (ICDAS) for Occlusal Caries… PMID:26381850 | this review only | not stated | not extracted yet | not extracted yet |
| de Paula 2011 In situ and in vitro comparison of laser fluorescence with visual inspection in detecting occlusal caries lesions DOI:10.1007/s10103-009-0731-y | this review only | not stated | not extracted yet | not extracted yet |
| de Paula 2011 In situ and in vitro comparison of laser fluorescence with visual inspection in detecting occlusal caries lesions. PMID:19784712 | this review only | not stated | not extracted yet | not extracted yet |
| Deery 1995 The Effect of Placing a Clear Pit and Fissure Sealant on the Validity and Reproducibility of Occlusal Caries Diagnosis DOI:10.1159/000262096 | this review only | not stated | not extracted yet | not extracted yet |
| Deery 1995 The effect of placing a clear pit and fissure sealant on the validity and reproducibility of occlusal caries diagnosis. PMID:8521440 | this review only | not stated | not extracted yet | not extracted yet |
| Erten 2005 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Erten 2005 The assessment of unaided visual examination, intraoral camera and operating microscope for the detection of occlusal caries lesions. PMID:15853104 | this review only | not stated | not extracted yet | not extracted yet |
| Francescut 2003 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Francescut 2003 Correlation between fissure discoloration, Diagnodent measurements, and caries depth: an in vitro study. PMID:14733470 | this review only | not stated | not extracted yet | not extracted yet |
| Fung 2004 Diagnostic comparison of three groups of examiners using visual and laser fluorescence methods to detect occlusal caries <i>in vitro</i> DOI:10.1111/j.1834-7819.2004.tb00052.x | this review only | not stated | not extracted yet | not extracted yet |
| Fung 2004 Diagnostic comparison of three groups of examiners using visual and laser fluorescence methods to detect occlusal caries in vitro. PMID:15293816 | this review only | not stated | not extracted yet | not extracted yet |
| Gray 1997 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Gray 1997 Fissure caries diagnosis and resulting treatment decisions by clinical community dental officers and general dental practitioners. PMID:9594734 | this review only | not stated | not extracted yet | not extracted yet |
| Heinrich-Weltzien 2002 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Heinrich-Weltzien 2002 Clinical evaluation of visual, radiographic, and laser fluorescence methods for detection of occlusal caries. PMID:12515052 | this review only | not stated | not extracted yet | not extracted yet |
| Huth 2008 Clinical performance of a new laser fluorescence device for detection of occlusal caries lesions in permanent molars DOI:10.1016/j.jdent.2008.08.013 | this review only | not stated | not extracted yet | not extracted yet |
| Huth 2008 Clinical performance of a new laser fluorescence device for detection of occlusal caries lesions in permanent molars. PMID:18930575 | this review only | not stated | not extracted yet | not extracted yet |
| Ie 1995 Electrical Conductance of Fissure Enamel in Recently Erupted Molar Teeth as Related to Caries Status DOI:10.1159/000262048 | this review only | not stated | not extracted yet | not extracted yet |
| Ie 1995 Electrical conductance of fissure enamel in recently erupted molar teeth as related to caries status. PMID:7728835 | this review only | not stated | not extracted yet | not extracted yet |
| Ketley 1993 Visual and radiographic diagnosis of occlusal caries in first permanent molars and in second primary molars DOI:10.1038/sj.bdj.4808172 | this review only | not stated | not extracted yet | not extracted yet |
| Ketley 1993 Visual and radiographic diagnosis of occlusal caries in first permanent molars and in second primary molars. PMID:8494666 | this review only | not stated | not extracted yet | not extracted yet |
| Lussi 1993 Comparison of Different Methods for the Diagnosis of Fissure Caries without Cavitation DOI:10.1159/000261572 | this review only | not stated | not extracted yet | not extracted yet |
| Lussi 1993 Comparison of different methods for the diagnosis of fissure caries without cavitation. PMID:8242679 | this review only | not stated | not extracted yet | not extracted yet |
| Lussi 1995 In vivo Diagnosis of Fissure Caries Using a New Electrical Resistance Monitor DOI:10.1159/000262046 | this review only | not stated | not extracted yet | not extracted yet |
| Lussi 1995 In vivo diagnosis of fissure caries using a new electrical resistance monitor. PMID:7728833 | this review only | not stated | not extracted yet | not extracted yet |
| Lussi 2006 Performance of a new laser fluorescence device for the detection of occlusal caries in vitro DOI:10.1016/j.jdent.2005.11.002 | this review only | not stated | not extracted yet | not extracted yet |
| Lussi 2006 Performance of a new laser fluorescence device for the detection of occlusal caries in vitro. PMID:16431009 | this review only | not stated | not extracted yet | not extracted yet |
| Manton 2007 The Effect of Pit and Fissure Sealants on the Detection of Occlusal Caries in vitro DOI:10.1007/bf03262569 | this review only | not stated | not extracted yet | not extracted yet |
| Manton 2007 The effect of pit and fissure sealants on the detection of occlusal caries in vitro. PMID:17394890 | this review only | not stated | not extracted yet | not extracted yet |
| Mestriner 2005 Comparison of different methods for the occlusal dentine caries diagnosis DOI:10.1590/s1678-77572005000100007 | this review only | not stated | not extracted yet | not extracted yet |
| Mestriner 2005 Comparison of different methods for the occlusal dentine caries diagnosis. PMID:20944877 | this review only | not stated | not extracted yet | not extracted yet |
| Mortensen 2014 Detection of non-cavitated occlusal caries with impedance spectroscopy and laser fluorescence: an in vitro study. PMID:24799965 | this review only | not stated | not extracted yet | not extracted yet |
| Nytun 1992 Diagnosis of dentin involvement in occlusal caries based on visual and radiographic examination of the teeth DOI:10.1111/j.1600-0722.1992.tb01730.x | this review only | not stated | not extracted yet | not extracted yet |
| Nytun 1992 Diagnosis of dentin involvement in occlusal caries based on visual and radiographic examination of the teeth. PMID:1631482 | this review only | not stated | not extracted yet | not extracted yet |
| Pereira 2001 Caries Detection Methods: Can They Aid Decision Making for Invasive Sealant Treatment? DOI:10.1159/000047437 | this review only | not stated | not extracted yet | not extracted yet |
| Pereira 2001 Caries detection methods: can they aid decision making for invasive sealant treatment? PMID:11275666 | this review only | not stated | not extracted yet | not extracted yet |
| Reis 2006 Performance of methods of occlusal caries detection in permanent teeth under clinical and laboratory conditions DOI:10.1016/j.jdent.2005.04.002 | this review only | not stated | not extracted yet | not extracted yet |
| Reis 2006 Performance of methods of occlusal caries detection in permanent teeth under clinical and laboratory conditions. PMID:15970371 | this review only | not stated | not extracted yet | not extracted yet |
| Ricketts 1995 Clinical and radiographic diagnosis of occlusal caries. a study <i>in vitro</i> DOI:10.1111/j.1365-2842.1995.tb00205.x | this review only | not stated | not extracted yet | not extracted yet |
| Ricketts 1995 Clinical and radiographic diagnosis of occlusal caries: a study in vitro. PMID:7897553 | this review only | not stated | not extracted yet | not extracted yet |
| Rodrigues 2009 In vitro comparison of laser fluorescence performance with visual examination for detection of occlusal caries in permanent and primary… PMID:18373155 | this review only | not stated | not extracted yet | not extracted yet |
| Rodrigues 2009 The influence of PVC wrapping on the performance of two laser fluorescence devices on occlusal surfaces in vitro. PMID:19416005 | this review only | not stated | not extracted yet | not extracted yet |
| Rodrigues 2009 (Laser Med Sci) In vitro comparison of laser fluorescence performance with visual examination for detection of occlusal caries in permanent and primary… DOI:10.1007/s10103-008-0552-4 | this review only | not stated | not extracted yet | not extracted yet |
| Rodrigues 2009 (Photomed Laser Surg) The Influence of PVC Wrapping on the Performance of Two Laser Fluorescence Devices on Occlusal Surfaces <i>in Vitro</i> DOI:10.1089/pho.2008.2333 | this review only | not stated | not extracted yet | not extracted yet |
| Rodrigues 2011 Light-emitting diode and laser fluorescence-based devices in detecting occlusal caries DOI:10.1117/1.3631796 | this review only | not stated | not extracted yet | not extracted yet |
| Rodrigues 2011 Light-emitting diode and laser fluorescence-based devices in detecting occlusal caries. PMID:22029365 | this review only | not stated | not extracted yet | not extracted yet |
| Souza-Zaroni 2006 Validity and Reproducibility of Different Combinations of Methods for Occlusal Caries Detection: An in vitro Comparison DOI:10.1159/000092225 | this review only | not stated | not extracted yet | not extracted yet |
| Souza-Zaroni 2006 Validity and reproducibility of different combinations of methods for occlusal caries detection: an in vitro comparison. PMID:16707866 | this review only | not stated | not extracted yet | not extracted yet |
| Tranaeus 2004 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Tranaeus 2004 In vivo validity and reliability of IR fluorescence measurements for caries detection and quantification. PMID:15779494 | this review only | not stated | not extracted yet | not extracted yet |
| Wenzel 1991 Radiographic detection of occlusal caries in noncavitated teeth DOI:10.1016/0030-4220(91)90504-6 | this review only | not stated | not extracted yet | not extracted yet |
| Wenzel 1991 Radiographic detection of occlusal caries in noncavitated teeth. A comparison of conventional film radiographs, digitized film… PMID:1745523 | this review only | not stated | not extracted yet | not extracted yet |