Search review questions

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · Caries detection level

Full-mouth bleeding score (FMBS) · Adolescents/teenagers undergoing orthodontic treatment · 12 months, Adolescents

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Mixed dentition caries

Optical/esthetic improvement (DIAGNOdent reading) · Patients (mainly children) with white spot lesions (WSL) · 3 to 6 months, Severe lesions, DIAGNOdent score >14 (Gozetici et al. 2019)

Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances · 3-27 months follow-up

Periodontal disease (periodontitis) coincidence · Patients with ulcerative colitis (UC) and controls without IBD; adults, both sexes · Ulcerative colitis (UC) vs healthy controls

Iron deficiency anemia (IDA) · Preschool children (<6 years) · Overall

All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Adjusted for age/sex

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · Dentin detection level

Specificity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Approximal surface

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Adjusted for age/sex

Diagnostic accuracy on surfaces with pit and fissure sealants · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Pit and fissure sealants

Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · Dentin detection level

Mean dmft · Five-year-old preschool children in Sharjah · Males

Mean DMFT · School children aged 11-17 years in Sharjah · Overall

Radiographic proximal caries lesion progression · Patients with non-cavitated proximal (approximal) caries lesions (primary or permanent dentition) · Longest available follow-up, Caries risk: high

Dental caries prevalence · General Pakistani population (all ages and both sexes; predominantly children and adolescents) · Province: Punjab

Dental caries prevalence · Preschool children of incarcerated mothers in UAE prison nurseries · Overall

Oral health status (caries, gingivitis, calculus, treatment indices) · Children with cerebral palsy in the United Arab Emirates (Dubai)

Diagnostic accuracy for proximal caries detection (caries detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · Caries detection level

Maximum interincisor distance (mouth opening) · Adults (general and hospital populations assessed in case-control studies)

Mean DMFT · Children with cerebral palsy in Dubai · Overall

Optical/esthetic improvement (visual-tactile assessment) · Patients with post-orthodontic white spot lesions (WSL) · 4 weeks to 6 months, Spectroscopy delta-E (Knosel et al. 2013)

Outcome NR · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance…

Restorative index · Preschool children attending Al Ain pediatric dentistry department · Overall

Disease-free survival, adjuvant concurrent chemoradiation vs adjuvant radiotherapy (pooled) · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

DMFT (association with plaque) · Children aged 5-6 years in Ajman schools · Highest versus lowest plaque category

Serum ferritin level · Preschool children (<6 years) · Overall

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces

Sensitivity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Non-histology reference standard (excavation, radiographs, separation)

Enamel dissolution prevalence · Five-year-old preschool children in Sharjah · Overall

Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · Dentin detection level

Difference in specificity · Children or adults asymptomatic or suspected of enamel caries; extracted teeth · Analysis 1: fully within-person comparison

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · Dentin detection level

Outcome NR · Children/adolescents/adults or extracted teeth; target condition = non-cavitated enamel caries on PROXIMAL… · Up to 3 months between index test and reference standard (in vivo studies)

Exposed dentin prevalence · Five-year-old preschool children in Sharjah · Overall

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Setting: in vitro (non-CBCT)

White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances

Dental caries (presence) · Individuals in East Africa assessed for dental caries

Dental caries · Children

Number of teeth · Adults (general and hospital populations assessed in case-control studies)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

Mean dmft, overall · Preschool children in Abu Dhabi nurseries · Overall

Specificity for detection of enamel/early caries · Children or adults presenting asymptomatically or suspected of having enamel caries (clinical/in vivo studies);… · Up to 3 months between index test and reference standard (in vivo; in vitro no limit if stored appropriately)

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Sensitivity analysis: low dentine-caries prevalence <15%

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Permanent tooth caries

Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces

Dental caries prevalence · Preschool children in Abu Dhabi nurseries · Overall

Overall survival, adjuvant concurrent chemoradiation vs adjuvant radiotherapy · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer