Cochrane Review Group

Injuries

50 systematic reviews in Injuries ask 611 questions. 20.5% have no studies to answer them, 30.3% rest on very low certainty evidence and 17.7% reach moderate or high certainty.

Reviews

Questions

611

current versions

No studies

20.5%

Moderate or high

17.7%

No studies 125 · 20.5%Ungraded 22 · 3.6%Very low 185 · 30.3%Low 171 · 28%Moderate 77 · 12.6%High 31 · 5.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Injuries

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Intervention NR Crash‐related injury rates · drivers or passengers travelling in passenger or commercial vehicles Education, incentive, and engineering‐based interventions to promote the use of seat belts (2024) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Crash‐related mortality rates · drivers or passengers travelling in passenger or commercial vehicles Education, incentive, and engineering‐based interventions to promote the use of seat belts (2024) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Crash‐related injury rates · drivers or passengers travelling in passenger or commercial vehicles Education, incentive, and engineering‐based interventions to promote the use of seat belts (2024) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Crash‐related mortality rates · drivers or passengers travelling in passenger or commercial vehicles Education, incentive, and engineering‐based interventions to promote the use of seat belts (2024) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Crash‐related injury rates · drivers or passengers travelling in passenger or commercial vehicles Education, incentive, and engineering‐based interventions to promote the use of seat belts (2024) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Crash‐related mortality rates · drivers or passengers travelling in passenger or commercial vehicles Education, incentive, and engineering‐based interventions to promote the use of seat belts (2024) · Cochrane	no estimate extracted	NR	No studies
Intervention NR TXA given orally at a total dose of greater than 3 g pre‐incision and postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid,… Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee… (2024) · Cochrane	no estimate extracted	3 participants	Very low
Intervention NR TXA given intravenously and intra‐articularly at a total dose of 2 g pre‐incision and intraoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid,… Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee… (2024) · Cochrane	no estimate extracted	2 participants	Very low
Intervention NR TXA given intravenously at a total dose of 2 g pre‐incision and intraoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid,… Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee… (2024) · Cochrane	no estimate extracted	2 participants	Very low
Intervention NR EACA given intravenously · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid,… Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee… (2024) · Cochrane	no estimate extracted	NR	Very low
Intervention NR Fibrin (topical) · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid,… Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee… (2024) · Cochrane	no estimate extracted	NR	Very low
Intervention NR TXA given intravenously at a total dose of 2 g intraoperatively and postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid,… Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee… (2024) · Cochrane	no estimate extracted	2 participants	Very low

Reviews 50

Education, incentive, and engineering‐based interventions to promote the use of seat belts

Lourens, A, Sinclair, M, et al. · Cochrane Database of Systematic Reviews · 2024

Injuries

Thinnest evidence

Reviews 50

Education, incentive, and engineering‐based interventions to promote the use of seat belts

Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a systematic review and network meta‐analysis

Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery

Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures

Transfusion thresholds for guiding red blood cell transfusion

Glucocorticoid with cyclophosphamide for oral paraquat poisoning

Interventions to reduce body temperature to 35 ⁰C to 37 ⁰C in adults and children with traumatic brain injury

Mobility management to prevent, reduce, or delay driving a car in teenagers

Hypertonic saline versus other intracranial pressure–lowering agents for people with acute traumatic brain injury

Random drug and alcohol testing for preventing injury in workers

Interventions for frostbite injuries

Decompressive craniectomy for the treatment of high intracranial pressure in closed traumatic brain injury

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice

Iron therapy for preoperative anaemia

Indomethacin for intracranial hypertension secondary to severe traumatic brain injury in adults

Intravenous iron therapy for non‐anaemic, iron‐deficient adults

Colloids versus crystalloids for fluid resuscitation in critically ill people

Pro‐coagulant haemostatic factors for the prevention and treatment of bleeding in people without haemophilia

Transfusion of red blood cells stored for shorter versus longer duration for all conditions

First aid interventions by laypeople for acute oral poisoning

Hypothermia for traumatic brain injury

Desmopressin use for minimising perioperative blood transfusion

Fitness training for cardiorespiratory conditioning after traumatic brain injury

Interventions for managing skeletal muscle spasticity following traumatic brain injury

Elevation of the head during intensive care management in people with severe traumatic brain injury