Cochrane · systematic review · CD006811
Interventions to reduce body temperature to 35 ⁰C to 37 ⁰C in adults and children with traumatic brain injury
Lewis, SR, Baker, PE, Andrews, PJD, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
InjuriesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
1
No studies
5
Included studies
NR
No studies 5 · 83.3%Ungraded 0 · 0%Very low 1 · 16.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Cooling to 35 °C to 37.5 °C for traumatic brain injury: pharmacological interventions
Population: adults with traumatic brain injury
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Poor outcome at the end of | no estimate extracted | NR | No studies |
Death from all causes during the | RR 2.86 [0.32, 25.24] | 1 study · 41 participants | Very low Downgraded: risk of bias, imprecision |
Serious intracranial haemorrhage | no estimate extracted | NR | No studies |
Extracranial haemorrhage | no estimate extracted | NR | No studies |
Abnormal intracranial pressure | no estimate extracted | NR | No studies |
Pneumonia or other serious infection | no estimate extracted | NR | No studies |