Cochrane · systematic review · CD010801
Transfusion of red blood cells stored for shorter versus longer duration for all conditions
Shah, A, Brunskill, SJ, Desborough, MJR, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
InjuriesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 37.5%Low 2 · 25%Moderate 3 · 37.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Transfusion of RBCs of shorter vs longer storage duration
Population: all conditions
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality: in‐hospital mortality (within 24 hours) Transfusion of RBCs of shorter vs longer storage duration | RR 1.71 [0.41, 7.1] | 1 study · 290 participants | Low Downgraded: indirectness |
Mortality: in‐hospital mortality (within 7 days) Transfusion of RBCs of shorter vs longer storage duration | RR 3 [0.13, 71.34] | 1 study · 74 participants | Very low Downgraded: indirectness |
Mortality: time‐point not defined Transfusion of RBCs of shorter vs longer storage duration | RR 2.25 [0.55, 9.17] | 1 study · 17 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Mortality: short term (up to 30 days) Transfusion of RBCs of shorter vs longer storage duration | RR 1.44 [0.46, 4.48] | 1 study · 290 participants | Low Downgraded: indirectness |
Transfusion of RBCs of shorter vs standard practice storage duration
Population: all conditions
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality: in‐hospital mortality (time points varied) Transfusion of RBCs of shorter vs standard practice storage duration | RR 1.05 [0.97, 1.14] | 4 studies · 25754 participants | Moderate Downgraded: risk of bias |
Mortality: in‐ICU mortality Transfusion of RBCs of shorter vs standard practice storage duration | RR 1.06 [0.98, 1.15] | 3 studies · 13066 participants | Moderate Downgraded: risk of bias, imprecision, indirectness |
Mortality: short‐term mortality (up to 30 days) ‐ neonates Transfusion of RBCs of shorter vs standard practice storage duration | RR 0.3 [0.01, 7.02] | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Mortality: short‐term mortality (up to 30 days) ‐ adults Transfusion of RBCs of shorter vs standard practice storage duration | RR 1.04 [0.96, 1.13] | 4 studies · 7510 participants | Moderate Downgraded: risk of bias, imprecision, indirectness |