Cochrane · systematic review · CD012980

Interventions for frostbite injuries

Lorentzen, AK, Davis, C, Penninga, L · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

InjuriesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
12
No studies
9
Included studies
NR
No studies 9 · 42.9%Ungraded 0 · 0%Very low 12 · 57.1%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings

Population: people with severe frostbite injuries
7 questions
OutcomeEffectEvidenceStatus / GRADE
Incidence of amputation in participants (3‐month
RR 0.051 study · 31 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Adverse events
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision, indirectness
Acute pain
no estimate extractedNRNo studies
Chronic pain
no estimate extractedNRNo studies
Withdrawal from intervention due to adverse events
no estimate extracted1 study · 31 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Occupational effects
no estimate extractedNRNo studies
Mortality
no estimate extracted1 study · 31 participantsVery low
Downgraded: risk of bias, imprecision, indirectness

Summary of findings

Population: people with severe frostbite injuries
7 questions
OutcomeEffectEvidenceStatus / GRADE
Incidence of amputation in participants (3‐month
RR 0.311 study · 31 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Adverse events
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision, indirectness
Acute pain
no estimate extractedNRNo studies
Chronic pain
no estimate extractedNRNo studies
Withdrawal from intervention due to adverse events
no estimate extracted1 study · 31 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Occupational effects
no estimate extractedNRNo studies
Mortality
no estimate extracted1 study · 31 participantsVery low
Downgraded: risk of bias, imprecision, indirectness

Summary of findings

Population: people with severe frostbite injuries
7 questions
OutcomeEffectEvidenceStatus / GRADE
Incidence of amputations in participants (3‐month
RR 0.141 study · 32 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Adverse events
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision, indirectness
Acute pain
no estimate extractedNRNo studies
Chronic pain
no estimate extractedNRNo studies
Withdrawal from intervention due to adverse events
no estimate extracted1 study · 32 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Occupational effects
no estimate extractedNRNo studies
Mortality
no estimate extracted1 study · 32 participantsVery low
Downgraded: risk of bias, imprecision, indirectness