Cochrane Review Group

ENT

76 systematic reviews in ENT ask 806 questions. 36.4% have no studies to answer them, 30.3% rest on very low certainty evidence and 11.5% reach moderate or high certainty.

Reviews
76
Questions
806
current versions
No studies
36.4%
Moderate or high
11.5%
No studies 293 · 36.4%Ungraded 6 · 0.7%Very low 244 · 30.3%Low 170 · 21.1%Moderate 85 · 10.5%High 8 · 1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Betahistine vs placebo/no treatment
Improvement in vertigo frequency · Ménière’s disease
Systemic pharmacological interventions for Ménière’s disease (2023) · Cochrane
RR 1.5 [0.98, 2.29]1 study · 70 participantsVery low
Betahistine vs placebo/no treatment
Improvement in vertigo frequency · Ménière’s disease
Systemic pharmacological interventions for Ménière’s disease (2023) · Cochrane
RR 1.11 [0.93, 1.32]1 study · 62 participantsVery low
Betahistine vs placebo/no treatment
Vertigo global score · Ménière’s disease
Systemic pharmacological interventions for Ménière’s disease (2023) · Cochrane
no estimate extracted1 study · 34 participantsVery low
Betahistine vs placebo/no treatment
Change in vertigo frequency · Ménière’s disease
Systemic pharmacological interventions for Ménière’s disease (2023) · Cochrane
no estimate extracted2 studies · 117 participantsVery low
Betahistine vs placebo/no treatment
Change in vertigo frequency · Ménière’s disease
Systemic pharmacological interventions for Ménière’s disease (2023) · Cochrane
no estimate extracted1 study · 214 participantsVery low
Betahistine vs placebo/no treatment
Serious adverse events · Ménière’s disease
Systemic pharmacological interventions for Ménière’s disease (2023) · Cochrane
RR 1.2 [0.63, 2.29]1 study · 220 participantsVery low
Diuretic vs placebo/no treatment
Improvement in vertigo frequency · Ménière’s disease
Systemic pharmacological interventions for Ménière’s disease (2023) · Cochrane
RR 1.69 [1.13, 2.53]1 study · 70 participantsVery low
Diuretic vs placebo/no treatment
Change in vertigo frequency · Ménière’s disease
Systemic pharmacological interventions for Ménière’s disease (2023) · Cochrane
no estimate extracted1 study · 220 participantsVery low
Beta‐blockers vs placebo
Improvement in vertigo · people with vestibular migraine
Pharmacological interventions for prophylaxis of vestibular migraine (2023) · Cochrane
no estimate extractedNRNo studies
Beta‐blockers vs placebo
Serious adverse events · people with vestibular migraine
Pharmacological interventions for prophylaxis of vestibular migraine (2023) · Cochrane
RR 0.63 [0.24, 1.67]1 study · 121 participantsVery low
Calcium channel blockers vs no intervention
Improvement in vertigo severity · people with vestibular migraine
Pharmacological interventions for prophylaxis of vestibular migraine (2023) · Cochrane
RR 1.45 [1.01, 2.07]1 study · 48 participantsVery low
Calcium channel blockers vs no intervention
Improvement in vertigo frequency · people with vestibular migraine
Pharmacological interventions for prophylaxis of vestibular migraine (2023) · Cochrane
RR 1.65 [0.8, 3.41]1 study · 23 participantsVery low

Reviews 76

Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery

Lourijsen, E, Avdeeva, K, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
7 questions

Systemic pharmacological interventions for Ménière’s disease

Webster, KE, Galbraith, K, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
8 questions

Pharmacological interventions for prophylaxis of vestibular migraine

Webster, KE, Dor, A, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
7 questions

Pharmacological interventions for persistent postural‐perceptual dizziness (PPPD)

Webster, KE, Harrington-Benton, NA, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
3 questions

Ventilation tubes (grommets) for otitis media with effusion (OME) in children

MacKeith, S, Mulvaney, CA, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
16 questions

Lifestyle and dietary interventions for Ménière’s disease

Webster, KE, George, B, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
9 questions

Intratympanic corticosteroids for Ménière’s disease

Webster, KE, Lee, A, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
7 questions

Intratympanic gentamicin for Ménière’s disease

Webster, KE, Galbraith, K, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
6 questions

Positive pressure therapy for Ménière’s disease

Webster, KE, George, B, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
4 questions

Surgical interventions for Ménière’s disease

Lee, A, Webster, KE, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
6 questions

Adenoidectomy for otitis media with effusion (OME) in children

MacKeith, S, Mulvaney, CA, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
16 questions

Autoinflation for otitis media with effusion (OME) in children

Webster, KE, Mulvaney, CA, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
4 questions

Antibiotics for otitis media with effusion (OME) in children

Mulvaney, CA, Galbraith, K, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
8 questions

Topical and oral steroids for otitis media with effusion (OME) in children

Mulvaney, CA, Galbraith, K, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
16 questions

Non‐pharmacological interventions for prophylaxis of vestibular migraine

Webster, KE, Dor, A, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
10 questions

Pharmacological interventions for acute attacks of vestibular migraine

Webster, KE, Dor, A, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
3 questions

Non‐pharmacological interventions for persistent postural‐perceptual dizziness (PPPD)

Webster, KE, Kamo, T, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
11 questions

Intratympanic corticosteroids for sudden sensorineural hearing loss

Plontke, SK, Meisner, C, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
36 questions

Antihistamines for motion sickness

Karrim, N, Byrne, R, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
24 questions

Ginkgo biloba for tinnitus

Sereda, M, Xia, J, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
10 questions

Interventions for the treatment of persistent post‐COVID‐19 olfactory dysfunction

O'Byrne, L, Webster, KE, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
14 questions

Interventions for the prevention of persistent post‐COVID‐19 olfactory dysfunction

Webster, KE, O'Byrne, L, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
17 questions

Topical azole treatments for otomycosis

Lee, A, Tysome, JR, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
4 questions

Systemic antibiotics for chronic suppurative otitis media

Chong, L-Y, Head, K, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
29 questions

Topical versus systemic antibiotics for chronic suppurative otitis media

Chong, L-Y, Head, K, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
21 questions