Cochrane · systematic review · CD015187

Pharmacological interventions for prophylaxis of vestibular migraine

Webster, KE, Dor, A, Galbraith, K, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

ENTAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 4 · 57.1%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Beta‐blockers compared to placebo for prophylaxis of vestibular migraine

Population: people with vestibular migraine
3 questions
OutcomeEffectEvidenceStatus / GRADE
Improvement in vertigo
Beta‐blockers vs placebo
no estimate extractedNRNo studies
Change in vertigo frequency
Beta‐blockers vs placebo
no estimate extracted1 study · 114 participantsLow
Downgraded: risk of bias
Serious adverse events
Beta‐blockers vs placebo
RR 0.63 [0.24, 1.67]1 study · 121 participantsVery low
Downgraded: risk of bias

Calcium channel blockers compared to no intervention for prophylaxis of vestibular migraine

Population: people with vestibular migraine
4 questions
OutcomeEffectEvidenceStatus / GRADE
Improvement in vertigo severity
Calcium channel blockers vs no intervention
RR 1.45 [1.01, 2.07]1 study · 48 participantsVery low
Downgraded: risk of bias
Improvement in vertigo frequency
Calcium channel blockers vs no intervention
RR 1.65 [0.8, 3.41]1 study · 23 participantsVery low
Downgraded: risk of bias, imprecision
Change in vertigo frequency
Calcium channel blockers vs no intervention
no estimate extracted1 study · 23 participantsVery low
Downgraded: risk of bias, imprecision
Serious adverse events
Calcium channel blockers vs no intervention
no estimate extractedNRNo studies