evidence/gaps
Cochrane · systematic review · CD015249

Surgical interventions for Ménière’s disease

Lee, A, Webster, KE, George, B, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

ENTAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
3
No studies
3
Included studies
NR
No studies 3 · 50%Ungraded 0 · 0%Very low 3 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Ventilation tubes compared to no treatment for Ménière’s disease

Population: Ménière’s disease
3 questions
OutcomeEffectEvidenceStatus / GRADE
Improvement in frequency of vertigo (complete resolution) at > 12 months
Ventilation tubes vs no treatment
RR 1.55 [1.22, 1.97]1 study · 133 participantsVery low
Change in frequency of vertigo
Ventilation tubes vs no treatment
no estimate extractedNRNo studies
Serious adverse events
Ventilation tubes vs no treatment
no estimate extractedNRNo studies

Endolymphatic sac decompression compared to placebo (sham surgery) for Ménière’s disease

Population: adults with Ménière’s disease
3 questions
OutcomeEffectEvidenceStatus / GRADE
Improvement in vertigo (complete resolution) at 6 to ≤ 12 months (12 months)
Endolymphatic sac decompression vs placebo (sham surgery)
RR 1.3 [0.86, 1.96]1 study · 30 participantsVery low
Downgraded: risk of bias
Change in vertigo at 6 to ≤ 12 months (12 months)
Endolymphatic sac decompression vs placebo (sham surgery)
no estimate extracted1 study · 29 participantsVery low
Downgraded: risk of bias
Serious adverse events
Endolymphatic sac decompression vs placebo (sham surgery)
no estimate extractedNRNo studies