Cochrane · systematic review · CD013514
Ginkgo biloba for tinnitus
Sereda, M, Xia, J, Scutt, P, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
ENTAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
7
No studies
3
Included studies
NR
No studies 3 · 30%Ungraded 0 · 0%Very low 4 · 40%Low 3 · 30%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Ginkgo biloba compared to placebo for tinnitus
Population: adults with tinnitus
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Tinnitus symptom severity Ginkgo biloba vs placebo | no estimate extracted | 2 studies · 85 participants | Very low Downgraded: risk of bias, imprecision, indirectness, publication bias |
Serious adverse effects (bleeding or seizures) Yes or no Ginkgo biloba vs placebo | no estimate extracted | 4 studies · 1154 participants | Low Downgraded: risk of bias, imprecision |
Tinnitus loudness Ginkgo biloba vs placebo | no estimate extracted | 1 study · 73 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Health‐related quality of life Ginkgo biloba vs placebo | no estimate extracted | 1 study · 60 participants | Low Downgraded: risk of bias, imprecision |
Other adverse effects (gastrointestinal upset, headache, allergic reaction) Yes or no Ginkgo biloba vs placebo | RR 0.91 [0.52, 1.6] | 4 studies · 1175 participants | Low Downgraded: risk of bias, imprecision |
Gingko biloba with concurrent intervention versus concurrent intervention only
Population: adults with tinnitus
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Tinnitus symptom severity Gingko biloba with concurrent intervention vs concurrent intervention only | no estimate extracted | 1 study · 22 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Serious adverse effects (bleeding or seizures) Gingko biloba with concurrent intervention vs concurrent intervention only | no estimate extracted | NR | No studies |
Tinnitus loudness Gingko biloba with concurrent intervention vs concurrent intervention only | no estimate extracted | 1 study · 22 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Health‐related quality of life Gingko biloba with concurrent intervention vs concurrent intervention only | no estimate extracted | NR | No studies |
Other adverse effects (gastrointestinal upset, headache, allergic reaction) Gingko biloba with concurrent intervention vs concurrent intervention only | no estimate extracted | NR | No studies |