Cochrane · systematic review · CD009289

Topical azole treatments for otomycosis

Lee, A, Tysome, JR, Saeed, SR · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

ENTAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 75%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Clotrimazole compared to another azole for otomycosis

Population: patients with otomycosis
4 questions
OutcomeEffectEvidenceStatus / GRADE
Complete clinical resolution
Clotrimazole vs another azole
RR 0.8 [0.59, 1.07]3 studies · 439 participantsVery low
Downgraded: risk of bias, inconsistency
Significant adverse events
Clotrimazole vs another azole
no estimate extracted1 study · 174 participantsVery low
Downgraded: imprecision
Mycological resolution
Clotrimazole vs another azole
RR 1.01 [0.96, 1.06]1 study · 174 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Other adverse events
Clotrimazole vs another azole
RR 0.79 [0.18, 3.41]1 study · 174 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness