Cochrane Review Group

Airways

216 systematic reviews in Airways ask 2,325 questions. 10.7% have no studies to answer them, 11.9% rest on very low certainty evidence and 40.5% reach moderate or high certainty.

Reviews

216

Questions

2,325

current versions

No studies

10.7%

Moderate or high

40.5%

No studies 249 · 10.7%Ungraded 107 · 4.6%Very low 276 · 11.9%Low 751 · 32.3%Moderate 718 · 30.9%High 224 · 9.6%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Airways

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Psychological interventions vs usual care, no intervention, or treatment with no psychological component Symptoms of anxiety · adolescents with asthma Psychological interventions for asthma in children and adolescents (2024) · Cochrane	no estimate extracted	5 studies · 431 participants	Very low
Psychological interventions vs usual care, no intervention, or treatment with no psychological component Symptoms of depression · adolescents with asthma Psychological interventions for asthma in children and adolescents (2024) · Cochrane	no estimate extracted	2 studies · 166 participants	Very low
Psychological interventions vs usual care, no intervention, or treatment with no psychological component Medical contacts Assessed as hospital admissions, ED presentations or asthma‐related urgent care visits. · adolescents with asthma Psychological interventions for asthma in children and adolescents (2024) · Cochrane	no estimate extracted	5 studies · 636 participants	Very low
Psychological interventions vs usual care, no intervention, or treatment with no psychological component Asthma attacks · adolescents with asthma Psychological interventions for asthma in children and adolescents (2024) · Cochrane	no estimate extracted	3 studies · 129 participants	Very low
Psychological interventions vs usual care, no intervention, or treatment with no psychological component Asthma symptoms · adolescents with asthma Psychological interventions for asthma in children and adolescents (2024) · Cochrane	no estimate extracted	11 studies · 720 participants	Very low
Psychological interventions vs usual care, no intervention, or treatment with no psychological component Medication use · adolescents with asthma Psychological interventions for asthma in children and adolescents (2024) · Cochrane	no estimate extracted	8 studies · 822 participants	Very low
Psychological interventions vs usual care, no intervention, or treatment with no psychological component Quality of life · adolescents with asthma Psychological interventions for asthma in children and adolescents (2024) · Cochrane	no estimate extracted	6 studies · 653 participants	Very low
Triple therapy vs LABA/LAMA combination Outcomes (weighted · people with stable COPD Inhaled corticosteroids with combination inhaled long‐acting beta2‐agonists and long‐acting muscarinic… (2023) · Cochrane	no estimate extracted	NR	No studies
Carbonic anhydrase inhibitors vs inactive control cAHI · adults with central sleep apnoea associated with heart failure Pharmacological treatment for central sleep apnoea in adults (2023) · Cochrane	no estimate extracted	1 study · 12 participants	Very low
Anxiolytics vs inactive control Cardiovascular mortality · adults with central sleep apnoea associated with heart failure Pharmacological treatment for central sleep apnoea in adults (2023) · Cochrane	no estimate extracted	NR	No studies
Anxiolytics vs inactive control Serious adverse events · adults with central sleep apnoea associated with heart failure Pharmacological treatment for central sleep apnoea in adults (2023) · Cochrane	no estimate extracted	NR	No studies
Anxiolytics vs inactive control Quality of sleep · adults with central sleep apnoea associated with heart failure Pharmacological treatment for central sleep apnoea in adults (2023) · Cochrane	no estimate extracted	NR	No studies

Reviews 216

Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease

Poole, P, Sathananthan, K, et al. · Cochrane Database of Systematic Reviews · 2019

Airways

Thinnest evidence

Reviews 216

Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease

Intra‐pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult parapneumonic effusions and empyema

Pressure modification or humidification for improving usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea

Inhaled steroids with and without regular formoterol for asthma: serious adverse events

Inhaled corticosteroids in children with persistent asthma: effects of different drugs and delivery devices on growth

Positional therapy for obstructive sleep apnoea

School‐based self‐management interventions for asthma in children and adolescents: a mixed methods systematic review

Statins versus placebo for people with chronic obstructive pulmonary disease

Phosphodiesterase 5 inhibitors for pulmonary hypertension

Prostacyclin for pulmonary arterial hypertension

Once daily long‐acting beta2‐agonists and long‐acting muscarinic antagonists in a combined inhaler versus placebo for chronic obstructive pulmonary disease

Head‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease

Speech and language therapy for management of chronic cough

Inhaled corticosteroids for bronchiectasis

Influenza vaccine for chronic obstructive pulmonary disease (COPD)

Antibiotics for exacerbations of asthma

Nurse‐led versus doctor‐led care for bronchiectasis

Antibiotics for prolonged wet cough in children

Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease

Inhaled steroids with and without regular salmeterol for asthma: serious adverse events

Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD)

Antibiotics for exacerbations of chronic obstructive pulmonary disease

Neuromuscular electrostimulation for adults with chronic obstructive pulmonary disease

Cyclophosphamide for connective tissue disease–associated interstitial lung disease

Combined aclidinium bromide and long‐acting beta2‐agonist for chronic obstructive pulmonary disease (COPD)