evidence/gaps
Cochrane · systematic review · CD002733

Influenza vaccine for chronic obstructive pulmonary disease (COPD)

Kopsaftis, Z, Wood‐Baker, R, Poole, P · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 0 · 0%Low 6 · 85.7%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Influenza vaccine compared to placebo for chronic obstructive pulmonary disease (COPD)

Population: chronic obstructive pulmonary disease (COPD)
7 questions
OutcomeEffectEvidenceStatus / GRADE
Total exacerbations per participant
Influenza vaccine vs placebo
no estimate extracted2 studies · 180 participantsLow
Downgraded: imprecision, indirectness
Early exacerbations per participant
Influenza vaccine vs placebo
no estimate extracted2 studies · 180 participantsLow
Downgraded: imprecision, indirectness
Late exacerbations per participant
Influenza vaccine vs placebo
no estimate extracted2 studies · 180 participantsLow
Downgraded: imprecision, indirectness
Days disability from respiratory illness
Influenza vaccine vs placebo
no estimate extractedNRNo studies
Hospital admissions
Influenza vaccine vs placebo
OR 0.33 [0.09, 1.24]2 studies · 180 participantsLow
Downgraded: imprecision, indirectness
Mortality
Influenza vaccine vs placebo
OR 0.87 [0.28, 2.7]2 studies · 180 participantsLow
Downgraded: imprecision, indirectness
Local effects at injection site
Influenza vaccine vs placebo
OR 5.57 [1.75, 17.71]1 study · 125 participantsLow
Downgraded: imprecision, indirectness