Cochrane · systematic review · CD004822
Antibiotics for prolonged wet cough in children
Marchant, JM, Petsky, HL, Morris, PS, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Antibiotics compared to placebo for prolonged wet cough in children
Population: prolonged wet cough in children
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Children not cured or substantially improved at Antibiotics vs placebo | OR 0.15 [0.07, 0.31] | 3 studies · 190 participants | Moderate Downgraded: risk of bias, imprecision |
Children with progression of the disease resulting in additional medical therapy (complications) (measured as proportion of participants) Antibiotics vs placebo | OR 0.1 [0.03, 0.34] | 2 studies · 125 participants | Moderate Downgraded: risk of bias, imprecision |
Children experiencing adverse effects of antibiotics (e.g. diarrhoea, nausea, skin rash, allergic reactions (measured as proportion of participants)) Antibiotics vs placebo | OR 1.88 [0.62, 5.69] | 3 studies · 190 participants | Low Downgraded: risk of bias, imprecision |