Cochrane · systematic review · CD010821

Neuromuscular electrostimulation for adults with chronic obstructive pulmonary disease

Hill, K, Cavalheri, V, Mathur, S, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
16
current version
GRADE rated
13
No studies
3
Included studies
NR
No studies 3 · 18.8%Ungraded 0 · 0%Very low 7 · 43.8%Low 6 · 37.5%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

NMES compared to usual care (with or without sham NMES) for COPD

Population: COPD
8 questions
OutcomeEffectEvidenceStatus / GRADE
Peripheral muscle force
NMES vs usual care (with or without sham NMES)
no estimate extracted6 studies · 159 participantsLow
Downgraded: risk of bias, imprecision
Peripheral muscle endurance/fatigability
NMES vs usual care (with or without sham NMES)
no estimate extracted2 studies · 35 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Thigh muscle size
NMES vs usual care (with or without sham NMES)
no estimate extracted4 studies · 124 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Exercise capacity
NMES vs usual care (with or without sham NMES)
no estimate extracted2 studies · 72 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Functional performance
NMES vs usual care (with or without sham NMES)
no estimate extractedNRNo studies
Symptoms of dyspnoea reported on completion of an exercise test
NMES vs usual care (with or without sham NMES)
no estimate extracted3 studies · 55 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Health‐related quality of life
NMES vs usual care (with or without sham NMES)
no estimate extracted2 studies · 72 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Minor adverse events assessed: related to intervention only (e.g. redness)
NMES vs usual care (with or without sham NMES)
RD 05 studies · 139 participantsLow
Downgraded: risk of bias, imprecision, inconsistency

NMES and exercise compared to exercise (with or without sham NMES) for COPD

Population: COPD
8 questions
OutcomeEffectEvidenceStatus / GRADE
Peripheral muscle force
NMES and exercise vs exercise (with or without sham NMES)
no estimate extracted4 studies · 84 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Peripheral muscle endurance/fatigability
NMES and exercise vs exercise (with or without sham NMES)
no estimate extractedNRNo studies
Thigh muscle size
NMES and exercise vs exercise (with or without sham NMES)
no estimate extractedNRNo studies
Exercise capacity
NMES and exercise vs exercise (with or without sham NMES)
no estimate extracted6 studies · 138 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Functional performance
NMES and exercise vs exercise (with or without sham NMES)
no estimate extracted2 studies · 44 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Symptoms of dyspnoea reported on completion of an exercise test
NMES and exercise vs exercise (with or without sham NMES)
no estimate extracted2 studies · 44 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Health‐related quality of life
NMES and exercise vs exercise (with or without sham NMES)
no estimate extracted5 studies · 122 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Minor adverse events assessed: related to intervention only (e.g. redness)
NMES and exercise vs exercise (with or without sham NMES)
no estimate extracted6 studies · 144 participantsLow
Downgraded: risk of bias, imprecision, inconsistency