Search review questions

Restoration success/failure · Children (5-7 years) with caries in primary teeth · 12 months

Treatment failure (annual failure rate) · Children with carious primary molars treated by pulpotomy (vital pulp therapy) · 1 year, University, Turkey (Sonmez and Duruturk 2010), Amalgam (A) arm

Difference in summary sensitivity (NMA, Analysis 2) · Transillumination vs Visual

Pocket closure (sites with PPD <=4 mm) · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive…

Early childhood caries (ECC) - association with genetically predicted expression of CDH17 (chr8q22.1) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), Population/community child cohorts: rural Appalachia (West Virginia, Pennsylvania) and Iowa (USA) and South West England; European / European non-Hispanic ancestry only, CDH17 (chr8q22.1); 23 (5) tissues; significant (Bonferroni p < 3.09x10-6)

Food preference · Children and adolescents aged 0-19 years · Predominantly high-income countries, Nonrandomized studies

Outcome NR · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance…

Oral problems prevalence · Pediatric leukemia patients in the United Arab Emirates · Overall

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Caries detection level

Specificity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Non-histology reference standard (excavation, radiographs, separation)

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Case-control studies of children and adults (China, India, Czech Republic, Turkey), Dentition: Mixed dentition caries

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies)

Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances · 1-24 months follow-up, Patients undergoing fixed (multibracket) orthodontic appliance treatment; clinical/dental setting; analysis at tooth level, Glass ionomer-based bonding agent

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Dentin detection level

Stability of crossbite correction (relapse of canine expansion) · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or… · 24 weeks after completion of expansion

Root resorption of the impacted canine or adjacent incisors and first premolars · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Case-control studies of children and adults (China, India, Czech Republic, Turkey), Ethnicity: Asian

Dental caries (presence) · Individuals in Ethiopia assessed for dental caries · Community-, school-, and hospital/clinic-based populations across regions of Ethiopia

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Caries detection level

Water samples with fluoride concentration below the acceptable range

Canine expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or… · post-treatment 3 weeks

Dental caries prevalence · Preschool children attending Al Ain pediatric dentistry department · Overall

Disease-free survival, chemotherapy regimen A vs regimen B · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

Change in diastolic blood pressure (DBP, mmHg) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension · Short term (follow-up 2 months), People diagnosed with periodontitis and hypertension

Samples with fluoride concentration outside the acceptable range · Brazilian cities with artificially fluoridated public water supplies · 1995-2013, Brazil, Sensitivity analysis excluding Silva et al.

Size of the lower jaw (arch length) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth · 6 months

Mean DMFT (decayed, missing, filled permanent teeth) · Individuals with permanent dentition in East Africa · Community- and school-based populations, East Africa, Ethiopia

Overall survival, induction cisplatin + 5-fluorouracil + docetaxel prior to concurrent chemoradiation (cisplatin) vs concurrent chemoradiation (cisplatin) · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro

Mean dmft (decayed, missing, filled primary teeth) · Children with primary dentition in East Africa · Community- and school-based populations, East Africa

Dental caries · Children · Community/population-based (multiple countries), Children's age: over 3 years

Severe early childhood caries · Children aged 5-6 years in Ajman schools · Overall

Dental caries prevalence · Somalia

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months

Locoregional control, induction cisplatin + 5-fluorouracil + docetaxel prior to concurrent chemoradiation vs concurrent chemoradiation · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

Size of the lower jaw (mandibular arch length, change) at 9 months · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth · 9 months

Probing depth (PD) · Adults (general and hospital populations assessed in case-control studies) · Hospital/clinic-based case-control studies from Asia, America and Europe

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Reference standard: enhanced visual (non-CBCT)

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Dentin detection level

Sensitivity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Primary/mixed dentition

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Permanent dentition (non-CBCT)

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 9 months

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious… · 12 months, Cavitated but not deep lesions, primary dentition

Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · In vivo (clinical); permanent posterior teeth, proximal surfaces, Dentin detection level

Specificity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies)

Dental caries prevalence · Preschool children in Sharjah day cares · Private day cares

Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 9 months

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Caries detection level

Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · In vivo (clinical); permanent posterior teeth, proximal surfaces, Dentin detection level

Incidence of eruption of the PDC into the mouth · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC) · 48 months (maximum; mITT)