Search review questions

Caries presence in primary teeth · For interventions, pregnant and lactating women; for outcomes, children up to 6 years of age · Children assessed at 5-6 yrs

Dental caries experience in primary dentition (early childhood caries) · Nigerian children with primary dentition (approximately 6 months to 5 years) · Primary dentition

White spot lesion incidence · Patients undergoing fixed orthodontic treatment · Before and after orthodontic treatment

Aesthetics · Children and adults (with or without carious lesions)

Mean DMFT (decayed, missing, filled teeth) · Adults · Overall

Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure · >=12 months, Normal pulp/reversible pulpitis

Dental caries / early childhood caries (ECC) · Children (approx. 4-18 years) · Country population: large

Secondary prevention of caries · Children and adults (with or without carious lesions) · 24 months, Primary dentition (coronal)

Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Study quality (NOS): good

Dental caries in children · Children of mothers assessed for smoking status during pregnancy (early childhood dental caries) · Exposure during pregnancy; caries assessed in early childhood, Dental examination: Visual/tactile examination

Early childhood caries experience (mean dmft) · Children younger than 71 months (under 6 years) · GNI <$5000

Caries arrest · Children and adults (with or without carious lesions) · 24 months, Mixed dentition (coronal)

DIAGNOdent white spot lesion measurement · Patients undergoing fixed orthodontic treatment · During orthodontic treatment

Periodontal pocket (odds), slum vs non-slum residence · Adult residents of slums and non-slum urban settings of LMICs · Cross-sectional, Slum vs non-slum urban (Osuh 2022, Nigeria)

Dental caries (prevalence) · Adults · Standard periodontitis definition

Dental caries risk · Institutionalized orphan children · Overall (pooled)

Biofilm morphology · Streptococcus mutans cultures and biofilms

Aesthetics · Children and adults (with or without carious lesions) · 6 to 12 months, Children

Bacterial adhesion (inhibition) · Streptococcus mutans (in vitro cultures and biofilms)

Photographic white spot lesion severity · Patients undergoing fixed orthodontic treatment · During orthodontic treatment

New white spot lesion incidence (and first-time bracket bond failure) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35) · During fixed appliance treatment

Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure · 12 months, 12-month follow-up

Aesthetics · Children and adults (with or without carious lesions)

Secondary prevention of caries · Children and adults (with or without carious lesions) · Primary and permanent dentition

Enamel demineralization (DIAGNOdent score) · Patients undergoing fixed orthodontic treatment · 1, 3, and 6 months after bonding

Proportion of ancient skulls with at least one non-carious cervical lesion (NCCL) · Ancient/prehistoric human skulls (excavated/archaeological skeletal remains) · Overall (all included studies)

Dental caries · Children (<18 years) with vs without dental caries · Allelic model (C vs T)

Enamel remineralization or anti-demineralization · Human teeth with early enamel lesions surrounding orthodontic brackets · 5 days to 6 months

Spontaneous space closure · Children and adolescents (<18 years) after extraction of a permanent first molar before eruption of the permanent… · Until eruption of the permanent second molar (median follow-up 4.0 years), Mandible

Dental caries (prevalence) · Adults · Age 30-64 years

Early childhood caries (ECC) · Children aged <6 years · Study quality (NOS): Low

Early childhood caries (ECC) · Children aged <6 years · Confounder adjustment: No

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar) · Until eruption of the permanent second molar (median follow-up 4.0 years), Mandible

Aesthetics · Children and adults (with or without carious lesions)

Dental caries · Children (<18 years) with vs without dental caries · Dominant model (CC+CT vs TT)

Early childhood caries (ECC) · Children with average age >3 years · Average age: >3 years

Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years · Fluorosis assessed when most permanent teeth of interest had erupted (6 to 18 years)

Veillonella spp. association with caries (qualitative)

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar) · Until eruption of the permanent second molar (median follow-up 4.0 years), Mandible

Early childhood caries (ECC) · Preschool children ≤6 years

Dental caries experience (mean DMFT) · Adult residents of slums and non-slum urban settings of LMICs · Cross-sectional

Dental caries in children · Children of mothers assessed for smoking status during pregnancy (early childhood dental caries) · Exposure during pregnancy; caries assessed in early childhood, Sample size: <=1000

Dental caries / early childhood caries (ECC) · Children (approx. 4-18 years) · Age: 7-15 years

Dental trauma prevalence · Adult residents of slums and non-slum urban settings of LMICs · Cross-sectional, Urban vs rural; slum vs non-slum

Dental caries (early childhood caries) · Narrative single study (Lima 2016): no nocturnal BF vs nocturnal BF at 16 months

Primary caries prevention · Children and adults (with or without carious lesions) · Permanent dentition (root)

Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Sample collection: saliva

Caries arrest · Children and adults (with or without carious lesions) · 24 months, Permanent dentition (root)

Dental caries · Children (<18 years) with vs without dental caries · Recessive model (AA vs AG+GG)

Negative predictive value for dental caries diagnosis · Children and adults with primary or permanent dentition · Overall