Non-Cochrane · aetiology · PM39709412
A systematic review and meta-analysis of the association between sugar intake and dental caries in Nigeria.
Akinsolu Folahanmi Tomiwa, Gbaja-Biamila Titilola Abike, Salako Abideen Olurotimi, et al. · BMC oral health · 2024 · PubMed · doi:10.1186/s12903-024-05309-z
Full textEvery question was extracted from the full text, figures and supplements by two independent LLM extractors, disagreements adjudicated. Rows cite where in the review the value comes from.
Questions
3
current version
GRADE rated
0
No studies
0
Included studies
15
linked below
No studies 0 · 0%Ungraded 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Nigerian individuals, including children and adults, with primary or permanent dentition | 14 cross-sectional studies, 10,272 participants (5091 female, 4261 male); 12 of 14 (85.7%) in Southwest Nigeria; conducted 2007 to 2023 |
| Intervention | Frequency and amount of sugar consumption (high or frequent sugar intake) | Sugar consumption measured by frequency (daily consumption, consumption at mealtimes, interval measures); high frequency defined as three or more times daily |
| Comparison | Individuals with lower or minimal sugar intake | Low sugar intake (fewer than three times daily) |
| Outcomes | Prevalence of dental caries in primary and permanent dentitions | Dental caries prevalence (present/absent); study-level caries prevalence ranged 3.7% to 48.9% |
| Study designs | Cross-sectional, cohort, and case-control (observational) studies; published, unpublished and grey literature; no language restriction | All 14 studies observational (cross-sectional); sample sizes 180 to 1549 |
| Timing | Not specified (cross-sectional prevalence; no follow-up period) | Not specified (cross-sectional) |
Search date: January 2001 to November 2024 (per Methods; Abstract states January 2001 to March 2023). Databases: PubMed; Web of Science; Scopus; Embase; reference lists of included articles
Questions and results
High-frequency sugar consumption (three or more times daily) vs Low sugar intake (fewer than three times daily)
Population: Nigerian individuals, including children and adults, with primary or permanent dentition
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries experience (prevalence) Overall (all dentitions pooled) High-frequency sugar consumption was associated with 18% higher but non-significant odds of dental caries in Nigeria (OR 1.18, 95% CI 0.87 to 1.59; I2=36%; ungraded). Source: Figure 2 (forest plot; overall diamond); Results 'Quantitative analysis'; Abstract · same question in other reviews | OR 1.18 [0.87, 1.59] | 7 studies | Ungraded |
High-frequency sugar consumption (three or more times daily) vs Low sugar intake (fewer than three times daily)
Population: Nigerian children with primary dentition (approximately 6 months to 5 years)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries experience in primary dentition (early childhood caries) Primary dentition In primary dentition, high-frequency sugar consumption was associated with slightly higher, non-significant odds of caries (OR 1.13, 95% CI 0.23 to 5.44), with high heterogeneity (I2=83%; ungraded). Source: Figure 3 (forest plot; overall diamond); Results 'Quantitative analysis' · same question in other reviews | OR 1.13 [0.23, 5.44] | 2 studies | Ungraded |
High-frequency sugar consumption (three or more times daily) vs Low sugar intake (fewer than three times daily)
Population: Nigerian individuals with permanent dentition (approximately 12 years and older)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries experience in permanent dentition Permanent dentition In permanent dentition, high-frequency sugar consumption was associated with non-significant 15% higher odds of caries (OR 1.15, 95% CI 0.88 to 1.52), with no heterogeneity (I2=0%; ungraded). Source: Figure 4 (forest plot; overall diamond); Results 'Quantitative analysis' · same question in other reviews | OR 1.15 [0.88, 1.52] | 4 studies | Ungraded |
Included primary studies 15
Open as a trial list| Study | Also included by | Outcomes it informs here | Trial PICO | Results |
|---|---|---|---|---|
| Olatosi 2021 matched by author and year (probable) | 1 other review | not stated | not extracted yet | not extracted yet |
| Ajayi 2014 matched by author and year (probable) | this review only | Dental caries experience in permanent dentition | not extracted yet | not extracted yet |
| Egbunah 2022 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| El Tantawi 2021 matched by author and year (probable) | this review only | Dental caries experience (prevalence) | not extracted yet | not extracted yet |
| Folayan 2007 matched by author and year (probable) | this review only | Dental caries experience in permanent dentition | not extracted yet | not extracted yet |
| Folayan 2012 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Folayan 2015 matched by author and year (probable) | this review only | Dental caries experience in primary dentition (early childhood caries) | not extracted yet | not extracted yet |
| Folayan 2016 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Folayan 2019 [Changes of spirographic parameters in type 2 diabetes mellitus]. PMID:20191918 | this review only | Dental caries experience in primary dentition (early childhood caries) | not extracted yet | not extracted yet |
| Folayan 2020 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Folayan 2022 matched by author and year (probable) | this review only | Dental caries experience in permanent dentition | not extracted yet | not extracted yet |
| Folayan, 2019 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Kalejaiye 2016 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Oyedele 2017 matched by author and year (probable) | this review only | Dental caries experience in permanent dentition | not extracted yet | not extracted yet |
| Oziegbe 2023 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match).
| Review | Shared studies | Jaccard |
|---|---|---|
| A systematic review and meta-analysis on early-childhood-caries global data. (2024) | 1 | 0.01 |