Search review questions

Caries arrest · Children and adults (with or without carious lesions)

Spontaneous space closure · Children and adolescents (<18 years) after extraction of a permanent first molar before eruption of the permanent… · Until eruption of the permanent second molar (median follow-up 4.0 years), Overall

Periodontal pocket depth (PPD) in OC cases vs controls · Adults in case-control studies (oral cancer patients vs healthy controls) · Not specified, PPD (periodontal pocket depth)

Overall success (composite of clinical and radiographic success) · Partial pulpotomy, immature teeth

Spontaneous space closure · Mandible: M2 Demirjian E-F vs G-H

Dental caries · Children (<18 years) with vs without dental caries · Recessive model (CC vs CA+AA)

Early childhood caries experience (mean dmft) · Children younger than 71 months (under 6 years) · Region: Africa

Determinants of oral diseases · Adults in LMIC urban and slum settings

Dental caries (ECC) · Preschool children under 6 years of age · First dental examination before age 6 years, Cohort studies; sensitivity analysis excluding Peres et al. (2017)

Incidence of new ICLs (proportion of tooth surfaces developing new lesions) · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new… · During fixed orthodontic treatment (development of new lesions), Overall (random-effects model)

Caries arrest · Children and adults (with or without carious lesions) · Primary and permanent dentition

Dental caries (ECC) · Preschool children under 6 years of age · First dental examination before age 6 years, Cohort studies; sensitivity analysis excluding studies 37, 41, 45, 53, and 56

Salivary S. mutans level · Patients with aggressive periodontitis · Overall

Dental caries (odds), slum vs non-slum residence · Adult residents of slums and non-slum urban settings of LMICs · Cross-sectional, Slum vs non-slum urban (Osuh 2022, Nigeria)

Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Region: Europe

Enamel demineralization (DIAGNOdent score) · Patients undergoing fixed orthodontic treatment · Baseline, 1 month, and 6 months after bonding

Overall success (composite of clinical and radiographic success) · Immature teeth, irreversible pulpitis

Change in Mutans streptococci (MS) count in saliva · Generally healthy individuals across all age groups (infants to elderly) · Post-consumption endpoint (varied durations across trials), Xylitol gum vs sorbitol gum (2 studies)

Dental caries · Children (<18 years) with vs without dental caries · Allelic model (T vs G)

Dental caries · Children (<18 years) with vs without dental caries · Allelic model (T vs C), Permanent dentition

Early childhood caries experience (mean dmft) · Children younger than 71 months (under 6 years) · GNI >$40000

Periodontitis (prevalence) · Adults · Crude OR

Regular toothbrushing usage (prevalence) · Children (<18 years) with intellectual and developmental disabilities (IDD) in India · Overall

Streptococcus mutans count · Patients undergoing fixed orthodontic treatment · 1 day, 2 months, and 6 months after bonding

Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure · >=12 months

Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years · Fluorosis assessed when most permanent teeth of interest had erupted (6 to 18 years)

Adverse effects · Children and adults (with or without carious lesions) · 48 hours to 24 months, Children

Caries presence in primary teeth · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes,… · Children assessed at 6 yrs

Salivary IL-6 level (pg/mL) · Children and young adults (3-25 years)

Demineralised lesion depth · Human tooth enamel specimens, sound/intact (in vitro) · After cariogenic acid challenge / pH cycling

Adverse events for mother or child · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6…

Dental caries (early childhood caries) · Preschool children (<6 years) · Cohort studies

Dental caries · Primary school children in Ethiopia

Primary caries prevention · Children and adults (with or without carious lesions)

Positive predictive value for dental caries diagnosis · Children and adults with primary or permanent dentition · Overall

dmft index score · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6…

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar) · Until eruption of the permanent second molar (median follow-up 4.0 years), Mandible

Dental caries in children · Children of mothers assessed for smoking status during pregnancy (early childhood dental caries) · Exposure during pregnancy; caries assessed in early childhood, Study region: Europe

Serum 25-hydroxyvitamin D level · Preschool children ≤6 years, Asia · Asia

Oral cancer (OC) · Adults in case-control studies of oral cancer; people assessed for periodontitis · Not specified, Overall (random-effects pooled estimate)

Caries arrest · Children and adults (with or without carious lesions) · 36 months, Permanent dentition (coronal)

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar) · Until eruption of the permanent second molar (median follow-up 4.0 years), Mandible

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar) · Until eruption of the permanent second molar (median follow-up 4.0 years), Mandible

Early childhood caries (ECC) · Children aged <6 years · Study quality (NOS): Moderate

Streptococcus mutans population · Patients undergoing fixed orthodontic treatment · 1 to 6 months after bonding

Mother self-reported oral health behaviours · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes,…

Association between orthodontic treatment duration and ICLs prevalence · Patients (permanent dentition) during or after fixed orthodontic treatment with fixed (multibracket) appliances · During or after fixed orthodontic treatment, By orthodontic treatment duration (subgroup meta-analysis; positive association, P=.01)

Aesthetics · Children and adults (with or without carious lesions) · 24 months, Children

Early childhood caries (ECC) · Children aged <6 years · Sample size: <300

Number of dental caries (carious pieces) · Adolescents (12-18 years) without background systemic disease · Population: adolescents (vs children; p-interaction=0.02)