Antibiotics vs no intervention
Serious adverse events · newborns with congenital syphilis
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
254 questions · 255 findings · 98 reviews
No studies found 91 · 35.7%GRADE not reported 15 · 5.9%Very low 85 · 33.3%Low 36 · 14.1%Moderate 21 · 8.2%High 7 · 2.7%
Acarbose vs no intervention
Serious adverse events · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
- Alpha‐glucosidase inhibitors for prevention or delay of type 2 diabetes mellitus and its associated complications in… 2018 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Nutrition support vs no intervention, placebo, or treatment
Serious adverse events · hospitalised adults at nutritional risk
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Chinese herbal medicines vs no intervention
Serious adverse events · patients with osteoporosis
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Ursodeoxycholic acid vs placebo or no intervention
Serious adverse events · patients with primary biliary cirrhosis.
It is very uncertain whether ursodeoxycholic acid changes serious adverse events compared with placebo or no intervention (very low certainty).
1 finding from 1 review
- RR 0.87 [0.68, 1.12]14 studies · 1382 participantsVery low
Spinal manipulative therapy vs inert interventions
Serious adverse events · Patients with acute low‐back pain
1 finding from 1 review
- no estimate extracted2 studies · 2 participantsGRADE not reported
Spinal manipulative therapy vs other interventions
Serious adverse events · Patients with acute low‐back pain
1 finding from 1 review
- no estimate extracted2 studies · 2 participantsGRADE not reported
Non‐absorbable disaccharides vs placebo or no intervention
Non‐serious adverse events (secondary outcome) · prevention and treatment of hepatic encephalopathy in people with cirrhosis
It is very uncertain whether non‐absorbable disaccharides changes non‐serious adverse events (secondary outcome) compared with placebo/no intervention (very low certainty).
1 finding from 1 review
- Non‐absorbable disaccharides versus placebo/no intervention and lactulose versus lactitol for the prevention and… 2016 · Cochrane Headline outcomes onlyRR 2.47 [1.24, 4.93]9 studies · 739 participantsVery low
Exercise vs no exercise
Serious adverse events ( · adult patients with an implantable cardioverter defibrillator
Exercise showed no clear difference in serious adverse events ( compared with no exercise at the end of the intervention (low certainty).
1 finding from 1 review
- Exercise‐based cardiac rehabilitation for adult patients with an implantable cardioverter defibrillator 2019 · Cochrane Headline outcomes onlyRR 1.05 [0.77, 1.44]2 studies · 356 participantsLow
Induced hypertension vs placebo or no intervention
Proportion of participants with ≥ 1 serious adverse events · people with acute subarachnoid haemorrhage
It is very uncertain whether induced hypertension changes proportion of participants with ≥ 1 serious adverse events compared with placebo or no intervention (very low certainty).
1 finding from 1 review
- Interventions for altering blood pressure in people with acute subarachnoid haemorrhage 2021 · Cochrane Headline outcomes onlyRR 2.24 [1.01, 4.99]2 studies · 61 participantsVery low
Band ligation vs no intervention or a sham procedure
Serious adverse events Idiopathic thrombocytopaenic purpura · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment
It is very uncertain whether band ligation changes serious adverse events Idiopathic thrombocytopaenic purpura compared with sham or no intervention (very low certainty).
1 finding from 1 review
- Band ligation versus sham or no intervention for primary prophylaxis of oesophageal variceal bleeding in children and… 2021 · Cochrane Headline outcomes onlyRR 0.28 [0.01, 6.25]1 study · 22 participantsVery low
Antibiotics vs placebo or no intervention
Non‐serious adverse events · farmworkers, soldiers, and people in endemic areas
It is very uncertain whether summary of findings table ‐ Antibiotics changes non‐serious adverse events compared with placebo or no intervention (very low certainty).
1 finding from 1 review
- RR 10.13 [2.4, 42.71]3 studies · 1909 participantsVery low
Vitamin D vs placebo or no intervention
Non‐serious adverse events · people with chronic liver diseases
1 finding from 1 review
- Vitamin D supplementation for chronic liver diseases in adults 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedVery low
Summary of findings: pioglitazone monotherapy vs intensive behaviour‐changing intervention
Serious adverse events (N) · people at increased risk for developing type 2 diabetes
1 finding from 1 review
- Pioglitazone for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk… 2020 · Cochrane Headline outcomes onlyno estimate extracted1 study · 103 participantsLow
Summary of findings: pioglitazone monotherapy vs no intervention
Serious adverse events (N) · people at increased risk for developing type 2 diabetes
Summary of findings: pioglitazone monotherapy showed no clear difference in serious adverse events (N) compared with no intervention (low certainty).
1 finding from 1 review
- Pioglitazone for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk… 2020 · Cochrane Headline outcomes onlyRR 0.71 [0.38, 1.32]7 studies · 1211 participantsLow
Ursodeoxycholic acid vs placebo or no intervention
Non‐serious adverse events · patients with primary biliary cirrhosis.
It is very uncertain whether ursodeoxycholic acid changes non‐serious adverse events compared with placebo or no intervention (very low certainty).
1 finding from 1 review
- RR 1.46 [0.83, 2.56]12 studies · 1277 participantsVery low
Radix Sophorae flavescentis vs placebo or no intervention
Proportion of participants with 1 or more serious adverse events · chronic hepatitis B
1 finding from 1 review
- Radix Sophorae flavescentis versus no intervention or placebo for chronic hepatitis B 2019 · Cochrane Headline outcomes onlyno estimate extracted10 studies · 1140 participantsVery low
Sclerotherapy vs no intervention
Serious adverse events and liver‐related morbidity: incidence of gastric varices · primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis
It is very uncertain whether sclerotherapy changes serious adverse events and liver‐related morbidity: incidence of… compared with no intervention (very low certainty).
1 finding from 1 review
- Sclerotherapy versus sham or no intervention for primary prophylaxis of oesophageal variceal bleeding in children with… 2020 · Cochrane Headline outcomes onlyRR 1.11 [0.36, 3.43]1 study · 108 participantsVery low
Fibrin‐based haemostatic agents vs placebo or no intervention
Serious adverse events Median · adults undergoing liver resection for cancer or benign disease
It is very uncertain whether fibrin‐based haemostatic agents changes serious adverse events Median compared with no intervention or placebo (very low certainty).
1 finding from 1 review
- Fibrin‐based haemostatic agents for reducing blood loss in adult liver resection 2023 · Cochrane Headline outcomes onlyRR 0.96 [0.88, 1.05]4 studies · 782 participantsVery low
High vs low dose pegylated interferon alpha‐2a or alpha‐2b
Serious adverse events · patients on HD with HCV infection
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for dialysis patients with hepatitis C virus (HCV) infection 2023 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found