Cochrane · systematic review · CD011561
Band ligation versus sham or no intervention for primary prophylaxis of oesophageal variceal bleeding in children and adolescents with chronic liver disease or portal vein thrombosis
Cifuentes, LI, Gattini, D, Torres-Robles, R, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
3
No studies
2
Included studies
NR
No studies 2 · 40%Ungraded 0 · 0%Very low 3 · 60%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Band ligation compared to sham or no intervention for primary prophylaxis of oesophageal variceal bleeding in children and adolescents with chronic liver disease or portal vein thrombosis
Population: children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality Band ligation vs sham or no intervention | RR 2.54 [0.11, 56.25] | 1 study · 22 participants | Very low Downgraded: risk of bias, imprecision |
Serious adverse events Idiopathic thrombocytopaenic purpura Band ligation vs sham or no intervention | RR 0.28 [0.01, 6.25] | 1 study · 22 participants | Very low Downgraded: risk of bias, imprecision |
Health‐related quality of life Band ligation vs sham or no intervention | no estimate extracted | NR | No studies |
Oesophageal variceal bleeding Band ligation vs sham or no intervention | RR 0.28 [0.03, 2.27] | 1 study · 22 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events considered not serious Band ligation vs sham or no intervention | no estimate extracted | NR | No studies |