Cochrane · systematic review · CD013096
Interventions for altering blood pressure in people with acute subarachnoid haemorrhage
Maagaard, M, Karlsson, WK, Ovesen, C, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
7
No studies
7
Included studies
NR
No studies 7 · 50%Ungraded 0 · 0%Very low 7 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Induced hypertension versus placebo or no intervention for people with acute subarachnoid haemorrhage
Population: people with acute subarachnoid haemorrhage
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death from all causes (primary outcome) Induced hypertension vs placebo or no intervention | RR 1.6 [0.57, 4.42] | 2 studies · 61 participants | Very low Downgraded: risk of bias, imprecision |
Death or dependency (primary outcome) Induced hypertension vs placebo or no intervention | RR 1.29 [0.78, 2.13] | 2 studies · 61 participants | Very low Downgraded: risk of bias, imprecision |
Proportion of participants with ≥ 1 serious adverse events Induced hypertension vs placebo or no intervention | RR 2.24 [1.01, 4.99] | 2 studies · 61 participants | Very low Downgraded: risk of bias, imprecision |
Quality of life Induced hypertension vs placebo or no intervention | no estimate extracted | 1 study · 20 participants | Very low Downgraded: risk of bias, imprecision |
Rebleeding Induced hypertension vs placebo or no intervention | no estimate extracted | 1 study · 41 participants | Very low Downgraded: risk of bias, imprecision |
Delayed cerebral ischaemia Induced hypertension vs placebo or no intervention | RR 0.33 [0.02, 7.32] | 1 study · 20 participants | Very low Downgraded: risk of bias, imprecision |
Hydrocephalus Induced hypertension vs placebo or no intervention | no estimate extracted | NR | No studies |
Lowered blood pressure versus placebo for people with subarachnoid haemorrhage
Population: people with acute subarachnoid haemorrhage
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death from all causes (primary outcome) Lowered blood pressure vs placebo | RR 0.52 [0.28, 0.98] | 1 study · 204 participants | Very low Downgraded: risk of bias, imprecision |
Death or dependency (primary outcome) Lowered blood pressure vs placebo | no estimate extracted | NR | No studies |
Proportion of participants with ≥ 1 serious adverse events Lowered blood pressure vs placebo | no estimate extracted | NR | No studies |
Quality of life Lowered blood pressure vs placebo | no estimate extracted | NR | No studies |
Rebleeding Lowered blood pressure vs placebo | no estimate extracted | NR | No studies |
Delayed cerebral ischaemia Lowered blood pressure vs placebo | no estimate extracted | NR | No studies |
Hydrocephalus Lowered blood pressure vs placebo | no estimate extracted | NR | No studies |