Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

65 questions · 67 findings · 40 reviews

No studies found 10 · 14.9%GRADE not reported 6 · 9%Very low 22 · 32.8%Low 19 · 28.4%Moderate 7 · 10.4%High 3 · 4.5%

Intervention not reported

All‐cause mortality · individuals with atrial fibrillation who are undergoing cardiac surgery

The intervention showed no clear difference in all‐cause mortality (low certainty).

1 finding from 1 review

Continuation vs discontinuation of antiplatelet therapy

Mortality within the longest · adults undergoing non‐cardiac surgery

Continuation showed no clear difference in all‐cause mortality (at longest compared with discontinuation of antiplatelet therapy (low certainty).

1 finding from 1 review

Summary of findings: Fibrin sealant vs usual care

All‐cause mortality up to 30 days · people aged 18 and over undergoing vascular surgery

It is very uncertain whether summary of findings: Fibrin sealant changes all‐cause mortality up to 30 days compared with usual care (very low certainty).

1 finding from 1 review

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Mortality within the longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

It is very uncertain whether pulmonary artery perfusion with blood changes all‐cause mortality within longest compared with no perfusion during cardiopulmonary bypass (very low certainty).

1 finding from 1 review

Perioperative restrictive fluid therapy vs goal‐directed fluid therapy

Mortality within the longest · adults receiving intravenous fluids while undergoing major non‐cardiac surgery

It is very uncertain whether perioperative restrictive fluid therapy changes all‐cause mortality (during longest compared with goal‐directed fluid therapy (very low certainty).

1 finding from 1 review

Epidural analgesia vs intravenous patient‐controlled analgesia

All‐cause mortality rate at 30 days · adults having abdominal surgery

Epidural analgesia showed no clear difference in all‐cause mortality rate at 30 days compared with intravenous patient‐controlled analgesia (low certainty).

1 finding from 1 review

Continuation vs discontinuation of antiplatelet therapy

All‐cause mortality (up to 30 days) · adults undergoing non‐cardiac surgery

Continuation showed no clear difference in all‐cause mortality (up to 30 days) compared with discontinuation of antiplatelet therapy (low certainty).

1 finding from 1 review