Cochrane · systematic review · CD010434
Epidural analgesia versus patient‐controlled intravenous analgesia for pain following intra‐abdominal surgery in adults
Salicath, JH, Yeoh, ECY, Bennett, MH · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 60%Moderate 2 · 40%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Epidural analgesia versus intravenous patient‐controlled analgesia for pain following intra‐abdominal surgery in adults
Population: adults undergoing intra‐abdominal surgery (including hysterectomies, radical prostatectomies, Caesarean sections, colorectal and upper gastrointestinal procedures)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain score at rest Epidural analgesia vs intravenous patient‐controlled analgesia | no estimate extracted | 7 studies · 384 participants | Moderate Downgraded: risk of bias |
Pain score on movement Epidural analgesia vs intravenous patient‐controlled analgesia | no estimate extracted | 2 studies · 80 participants | Low Downgraded: risk of bias, imprecision |
All‐cause mortality rate at 30 days Epidural analgesia vs intravenous patient‐controlled analgesia | RR 3.37 [0.72, 15.88] | 9 studies · 560 participants | Low Downgraded: risk of bias, imprecision |
Failure of analgesic technique requiring alternative approach (assessed at any time) Epidural analgesia vs intravenous patient‐controlled analgesia | RR 2.48 [1.13, 5.45] | 10 studies · 678 participants | Moderate Downgraded: risk of bias |
Adverse events (assessed at any time during Epidural analgesia vs intravenous patient‐controlled analgesia | RR 0.32 [0.03, 2.95] | 2 studies · 101 participants | Low Downgraded: risk of bias, imprecision |