Cochrane · systematic review · CD010954
Immunonutrition for patients undergoing surgery for head and neck cancer
Howes, N, Atkinson, C, Thomas, S, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
ENTAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 40%Low 3 · 60%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Immunonutrition compared to standard care for patients undergoing surgery for head and neck cancer
Population: patients undergoing surgery for head and neck cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Postoperative length of hospital stay (days) Immunonutrition vs standard care | MD 2.5 | 10 studies · 757 participants | Low Downgraded: imprecision |
Wound infection Immunonutrition vs standard care | RR 0.94 [0.7, 1.26] | 12 studies · 812 participants | Very low Downgraded: imprecision |
Fistula formation Immunonutrition vs standard care | RR 0.48 [0.27, 0.85] | 10 studies · 747 participants | Low Downgraded: imprecision |
Adverse events/tolerance of feeds Immunonutrition vs standard care | RR 1.33 [0.86, 2.06] | 9 studies · 719 participants | Very low Downgraded: imprecision |
All‐cause mortality Immunonutrition vs standard care | RR 1.33 [0.48, 3.66] | 14 studies · 776 participants | Low Downgraded: imprecision |