Cochrane · systematic review · CD011098
Pulmonary artery perfusion versus no perfusion during cardiopulmonary bypass for open heart surgery in adults
Buggeskov, KB, Grønlykke, L, Risom, EC, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
3
No studies
1
Included studies
NR
No studies 1 · 25%Ungraded 0 · 0%Very low 3 · 75%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Pulmonary artery perfusion with blood versus no perfusion during cardiopulmonary bypass for open heart surgery in adults
Population: adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality within longest Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass | Peto OR 1.78 [0.43, 7.4] | 4 studies · 210 participants | Very low Downgraded: imprecision |
Number of participants with pulmonary events within longest Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass | no estimate extracted | NR | No studies |
Participants with ≥ 1SAE within longest Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass | RR 1.12 [0.66, 1.89] | 3 studies · 180 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Last measured PaO2/FiO2 ratio (mmHg) in all trials, irrespective of overall risk of bias Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass | no estimate extracted | 3 studies · 119 participants | Very low Downgraded: risk of bias, imprecision, indirectness |