Cochrane · systematic review · CD012265
Probiotics for the postoperative management of term neonates after gastrointestinal surgery
Trivedi, A, Teo, E, Walker, KS · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 40%Very low 0 · 0%Low 3 · 60%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table ‐ Probiotics compared to placebo for neonates born from 35 weeks of gestation who have undergone gastrointestinal surgery
Population: neonates born from 35 weeks of gestation who have underdone gastrointestinal surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proven sepsis (positive bacterial culture, local or systemic) Summary of findings table ‐ Probiotics vs placebo | OR 0.64 [0.16, 2.55] | 1 study · 61 participants | Low Downgraded: imprecision |
All‐cause neonatal mortality (28 days) Summary of findings table ‐ Probiotics vs placebo | no estimate extracted | 0 studies · 0 participants | Ungraded |
Time to full enteral feeds in daysScale from: 0 to 100 Summary of findings table ‐ Probiotics vs placebo | no estimate extracted | 1 study · 61 participants | Low Downgraded: imprecision |
All‐cause mortality prior to discharge Summary of findings table ‐ Probiotics vs placebo | no estimate extracted | 1 study · 61 participants | Ungraded |
Non‐pathogenic intestinal microflora (relative abundance) Summary of findings table ‐ Probiotics vs placebo | no estimate extracted | 1 study · 39 participants | Low Downgraded: imprecision |