Cochrane Review Group
Neuromuscular
89 systematic reviews in Neuromuscular ask 1,173 questions. 25.7% have no studies to answer them, 22.8% rest on very low certainty evidence and 21% reach moderate or high certainty.
Reviews
89
Questions
1,173
current versions
No studies
25.7%
Moderate or high
21%
No studies 302 · 25.7%Ungraded 119 · 10.1%Very low 267 · 22.8%Low 239 · 20.4%Moderate 177 · 15.1%High 69 · 5.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Thinnest evidence
All no studies and very low questions| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Surgery vs corticosteroid injection Health‐related quality of life ‐ Long‐term improvement: > 3 months · people with carpal tunnel syndrome Surgical versus non‐surgical treatment for carpal tunnel syndrome (2024) · Cochrane | no estimate extracted | NR | No studies |
Surgery vs corticosteroid injection Adverse effects · people with carpal tunnel syndrome Surgical versus non‐surgical treatment for carpal tunnel syndrome (2024) · Cochrane | RR 1.49 [0.25, 8.7] | 2 studies · 90 participants | Very low |
Surgery vs corticosteroid injection Need for surgery or secondary surgery during · people with carpal tunnel syndrome Surgical versus non‐surgical treatment for carpal tunnel syndrome (2024) · Cochrane | RR 0.61 [0.25, 1.46] | 1 study · 163 participants | Very low |
Surgery vs splint Pain ‐ Long‐term improvement: > 3 months · people with carpal tunnel syndrome Surgical versus non‐surgical treatment for carpal tunnel syndrome (2024) · Cochrane | no estimate extracted | NR | No studies |
Surgery vs splint Adverse effects · people with carpal tunnel syndrome Surgical versus non‐surgical treatment for carpal tunnel syndrome (2024) · Cochrane | RR 2.11 [0.37, 12.12] | 2 studies · 210 participants | Very low |
Surgery vs corticosteroid injection Clinical improvement ‐ Long‐term improvement: > 3 months · people with carpal tunnel syndrome Surgical versus non‐surgical treatment for carpal tunnel syndrome (2024) · Cochrane | RR 1.23 [0.73, 2.06] | 3 studies · 187 participants | Very low |
Surgery vs corticosteroid injection Symptoms ‐ Long‐term improvement: > 3 months · people with carpal tunnel syndrome Surgical versus non‐surgical treatment for carpal tunnel syndrome (2024) · Cochrane | no estimate extracted | 2 studies · 118 participants | Very low |
Intravenous immunoglobulin vs prednisolone Change in mean disability score at 24 weeks or later · patients with CIDP Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy (2024) · Cochrane | no estimate extracted | NR | No studies |
Intravenous immunoglobulin vs plasma exchange Significant improvement in disability within 6 weeks · people with CIDP Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy (2024) · Cochrane | no estimate extracted | NR | No studies |
Intravenous immunoglobulin vs plasma exchange Change in mean disability score on Rankin scale · people with CIDP Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy (2024) · Cochrane | no estimate extracted | NR | No studies |
Intravenous immunoglobulin vs plasma exchange Change in mean disability score at 24 weeks or later · people with CIDP Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy (2024) · Cochrane | no estimate extracted | NR | No studies |
Alpha‐lipoic acid vs placebo Change in any validated quality of life score · people with DPN Alpha‐lipoic acid for diabetic peripheral neuropathy (2024) · Cochrane | no estimate extracted | NR | No studies |
Reviews 89
Recombinant human insulin‐like growth factor I (rhIGF‐I) for the treatment of amyotrophic lateral sclerosis/motor neuron disease
CochraneSoF table
5 questions
Creatine for amyotrophic lateral sclerosis/motor neuron disease
CochraneSoF table
3 questions
Decompressive surgery for treating nerve damage in leprosy
CochraneSoF table
6 questions
Enhanced glucose control for preventing and treating diabetic neuropathy
CochraneSoF table
13 questions
Lacosamide for neuropathic pain and fibromyalgia in adults
CochraneSoF table
8 questions
Ergonomic positioning or equipment for treating carpal tunnel syndrome
CochraneSoF table
6 questions
Exercise and mobilisation interventions for carpal tunnel syndrome
CochraneSoF table
8 questions
Treatment for Lambert‐Eaton myasthenic syndrome
CochraneSoF table
3 questions
Vaccination for preventing postherpetic neuralgia
CochraneSoF table
4 questions
Interventions for increasing ankle range of motion in patients with neuromuscular disease
CochraneSoF table
1 questions
Psychostimulants for hypersomnia (excessive daytime sleepiness) in myotonic dystrophy
CochraneSoF table
4 questions
Exercise for people with peripheral neuropathy
CochraneSoF table
9 questions
Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease
CochraneSoF table
7 questions
Plasma exchange for generalised myasthenia gravis
CochraneSoF table
7 questions