Cochrane · systematic review · CD002275

Plasma exchange for generalised myasthenia gravis

Gajdos, P, Chevret, S, Toyka, KV · Cochrane Database of Systematic Reviews · 2002 · Cochrane Library

NeuromuscularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 28.6%Low 4 · 57.1%Moderate 0 · 0%High 1 · 14.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Prednisone versus prednisone and plasma exchange (Gajdos 1983)

2 questions
OutcomeEffectEvidenceStatus / GRADE
Score (MMS) day 30
Prednisone vs prednisone and plasma exchange (Gajdos 1983)
no estimate extracted1 study · 14 participantsLow
Score (MMS) month 12
Prednisone vs prednisone and plasma exchange (Gajdos 1983)
no estimate extracted1 study · 14 participantsLow

IVIg versus plasma exchange for chronic myasthenia gravis (Ronager 2001)

2 questions
OutcomeEffectEvidenceStatus / GRADE
Week 1
IVIg vs plasma exchange
no estimate extracted1 study · 12 participantsVery low
Week 4
IVIg vs plasma exchange
no estimate extracted1 study · 12 participantsVery low

PE versus IVIg for myasthenia gravis exacerbation (Gajdos 1997)

1 question
OutcomeEffectEvidenceStatus / GRADE
Change in score (MMS) day 0 to day 15
PE vs IVIg
no estimate extracted1 study · 87 participantsHigh

PE versus no plasma exchange before thymectomy (Kamel 2009)

2 questions
OutcomeEffectEvidenceStatus / GRADE
Duration of MV (days)
PE vs no plasma exchange before thymectomy (Kamel 2009)
no estimate extracted1 study · 45 participantsLow
Duration of ICU stay (days)
PE vs no plasma exchange before thymectomy (Kamel 2009)
no estimate extracted1 study · 45 participantsLow