Cochrane · systematic review · CD005225

Creatine for amyotrophic lateral sclerosis/motor neuron disease

Pastula, DM, Moore, DH, Bedlack, RS · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library

Neuromuscular2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 3 · 100%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Creatine for amyotrophic lateral sclerosis

Population: patients with amyotrophic lateral sclerosis
3 questions
OutcomeEffectEvidenceStatus / GRADE
Tracheostomy‐free survival
no estimate extracted3 studies · 386 participantsHigh
ALSFRS‐R slope Change in ALSFRS‐R / month
no estimate extracted3 studies · 386 participantsHigh
FVC Slope Change in FVC / month
no estimate extracted2 studies · 211 participantsHigh