Findings

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Evidence found and GRADE certainty

2,745 questions · 4,389 findings · 203 reviews · Oral Health

No studies found 39 · 0.9%GRADE not reported 3,844 · 87.6%Very low 198 · 4.5%Low 137 · 3.1%Moderate 134 · 3.1%High 37 · 0.8%

Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)

Probing pocket depth · Adults (general and hospital populations assessed in case-control studies)

Probing depth is significantly increased in systemic sclerosis patients (SMD 3.10) with very high heterogeneity; certainty ungraded.

3 findings from 1 review

Conventional bitewing radiography (E-speed film) vs Histological validation of dental tissues (gold standard)

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)

Under in vitro conditions, conventional E-speed bitewing radiography had a pooled diagnostic odds ratio of 31.40 (95% CI 14.31, 68.93) for proximal caries detection at the dentin detection level; ungraded.

4 findings from 1 review
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Digital bitewing radiography, phosphor plate (PSP) vs Direct visual examination after tooth separation or bioptical cavity preparation

Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo)

Under in vivo conditions, phosphor-plate digital bitewing radiography had a pooled specificity of 0.60 (95% CI 0.20, 0.90) for proximal caries detection at the dentin detection level; ungraded.

4 findings from 1 review
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Private day care vs Public day care

Dental caries prevalence · Preschool children in Sharjah day cares

Caries prevalence was 77% in private day cares versus 22% in public day cares.

2 findings from 1 review

Laser fluorescence (DIAGNOdent 2190/pen) vs Direct visual examination after tooth separation or bioptical cavity preparation

Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo)

Under in vivo conditions, laser fluorescence (DIAGNOdent 2190) had a pooled specificity of 0.60 (95% CI 0.15, 0.93) for proximal caries detection at the dentin detection level; ungraded.

4 findings from 1 review
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Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)

Sites with probing depth >= 4 mm · Adults (general and hospital populations assessed in case-control studies)

Sites with probing depth >= 4 mm are significantly more frequent in SSc patients (SMD 2.07); certainty ungraded.

1 finding from 1 review

Dental imaging (analog or digital radiographs) vs Visual classification

Difference in sensitivity · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)

Imaging had lower sensitivity than visual classification in the fully within-person analysis.

1 finding from 1 review

TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs CC genotype vs CT/TT genotype (recessive model)

Dental caries susceptibility · Children and adults (no age limit) assessed for dental caries susceptibility

No significant association between the TaqI (rs731236 T>C) polymorphism and dental caries for mixed dentition caries under the recessive (CC vs CT/TT) model (OR 1.23, 95% CI 0.66 to 2.29); ungraded.

6 findings from 1 review
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Conventional bitewing radiography, F-speed film vs Histological validation of dental tissues (gold standard)

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)

Under in vitro conditions, conventional F-speed bitewing radiography had a pooled diagnostic odds ratio of 8.7 (95% CI 4.2, 18.1) for proximal caries detection at the dentin detection level; ungraded.

4 findings from 1 review
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TaqI (rs731236 T>C) polymorphism in the VDR gene (C allele / variant genotype) vs C allele vs T allele (allele contrast model)

Dental caries susceptibility · Children and adults (no age limit) assessed for dental caries susceptibility

No significant association between the TaqI (rs731236 T>C) polymorphism and dental caries in Caucasians under the allele contrast (C vs T) model (OR 1.16, 95% CI 0.90 to 1.50); ungraded.

6 findings from 1 review
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11-16 remaining teeth vs 25-32 remaining teeth

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, adults with 11-16 teeth had a higher cumulative incidence of ACVD-related events than adults with 25-32 teeth (RR 2.27, 95% CI 1.55 to 3.32; 4 cohort studies, I2=87%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

1 finding from 1 review

Intervention not reported

Dental caries prevalence · General population (children and adults) in East Africa

Caries prevalence in permanent dentition (>=12 years) was 50.2% (95% CI 38.4 to 62.1); certainty not graded.

1 finding from 1 review