Question · asked by 1 review

Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls): Probing pocket depth

Population
Adults (general and hospital populations assessed in case-control studies)
Intervention
Systemic sclerosis (SSc / scleroderma)
Comparison
SSc-free individuals (controls)
Outcome
Probing pocket depth

Probing depth is significantly increased in systemic sclerosis patients (SMD 3.10) with very high heterogeneity; certainty ungraded.

What each review found

Include earlier review versions
No studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)
Probing depth (PD) · Adults (general and hospital populations assessed in case-control studies) · Hospital/clinic-based case-control studies from Asia, America and Europe
Probing depth is significantly increased in systemic sclerosis patients (SMD 3.10) with very high heterogeneity; certainty ungraded.
Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies. (2021) All outcomes
SMD 3.101 [1.374, 4.829]7 studiesGRADE not reported
Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)
Probing depth (PD) · Adults (general and hospital populations assessed in case-control studies) · Hospital/clinic-based case-control studies from Asia, America and Europe, Other/non-Asia (Da Silva 2019, Iordache 2019, Isola 2017, Pischon 2016)
In the non-Asia subgroup, probing depth is significantly increased in SSc patients (SMD 4.86) with very high heterogeneity; certainty ungraded.
Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies. (2021) All outcomes
SMD 4.86 [1.61, 8.10]4 studiesGRADE not reported
Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)
Probing depth (PD) · Adults (general and hospital populations assessed in case-control studies) · Hospital/clinic-based case-control studies from Asia, America and Europe, Asia (Elimelech 2015, Leung 2011, Mayer 2013)
In the Asia subgroup, probing depth is significantly increased in SSc patients (SMD 1.11) with no heterogeneity; certainty ungraded.
Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies. (2021) All outcomes
SMD 1.113 [0.751, 1.476]3 studiesGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies.
2021 All outcomes
2020-0712Not applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.