Search review questions

Patient-reported outcomes (pain, discomfort and analgesic use) · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC) · Evening after extraction and one week later

Changes in intensity of pain (VAS 0 to 10) tested through tactile stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation · Medium term (24 hours to 2 months)

Periodontal disease (periodontitis) coincidence · Patients with inflammatory bowel disease (IBD) and controls without IBD; mostly adults (one pediatric study), both sexes · Hospital/clinic-based case-control and cross-sectional studies in 11 countries; 15 studies total (1748 participants: 1104 Crohn's disease, 534 ulcerative colitis, 110 IBD-form unspecified); 6 studies pooled for this analysis

Diagnostic accuracy for proximal caries detection (caries detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · In vivo (clinical); permanent posterior teeth, proximal surfaces, Caries detection level

Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or…

Dental caries prevalence · General population in Ethiopia (all ages, age range 6-100 years) · Community-, school-, and hospital/clinic-based populations across regions of Ethiopia, Tigray

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro

Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Caries detection level

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Primary dentition (non-CBCT)

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Proximal surfaces (CBCT)

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Dentin detection level

Tooth brushing less than once daily, males in 2016 · Nationally surveyed adolescents in the United Arab Emirates · Overall

Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 9 months

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Caries detection level

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Caries detection level

Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or…

Sensitivity · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous…

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Caries detection level

Dental caries · Children · Community/population-based (multiple countries), Children's age: 3 years or younger

Poor oral hygiene prevalence · Autistic children and young adults in Dubai · Overall

Swelling (7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1… · 7th day

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro

Changes in intensity of pain (VAS 0 to 10) tested through air blast stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation · Short term (0 to 24 hours)

Dental caries prevalence · General Pakistani population (all ages and both sexes; predominantly children and adolescents) · Pakistan (school-, community-, and hospital/clinic-based cross-sectional surveys), Dentition: primary

Reported improvement in the position of the ectopic canine measured from radiographs · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

Dental-care visit prevalence · Children with autism spectrum disorder in Dubai · Overall

Efficiency, costs or cost-effectiveness · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious… · Primary dentition

Patient-reported outcome measures (PROMs), including quality of life and pain · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

Pain (continuous, VAS 0-10 cm, 7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1… · 6th to 7th day

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Digital

Dental caries prevalence · General population in Ethiopia (all ages, age range 6-100 years) · Community-, school-, and hospital/clinic-based populations across regions of Ethiopia

Outcome NR · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

Change in diastolic blood pressure (DBP, mmHg) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension · Long term (follow-up 6 months), People diagnosed with periodontitis

Outcome NR · Teeth with previously applied restorations (secondary caries) or pit and fissure sealants; target condition =… · Up to 3 months between index test and reference standard (in vivo studies)

Upper incisors to maxilla (inclination, degrees) at 9 months · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth · 9 months

Simplified gingival index (s-GI) · Adolescents/teenagers undergoing orthodontic treatment · 1 month, Adolescents

Clinical attachment level (CAL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension · Long term, People diagnosed with periodontitis

Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 months

Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · In vivo (clinical); permanent posterior teeth, proximal surfaces, Dentin detection level

Dental caries (presence) · Individuals in East Africa assessed for dental caries · Community- and school-based populations, East Africa

Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces · in vivo

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces · in vivo

Mean dmft/DMFT · School children aged 12-14 years in Dubai schools · Overall

Dental caries · Healthy children and adolescents in the United Arab Emirates · UAE; schools/nurseries

Oral health problems (mucositis, caries, candidiasis) · Children with leukemia in the United Arab Emirates · UAE

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces · in vivo

Success rate at 5 years · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible;… · 5 years