Search review questions

Generalized gingivitis prevalence · Autistic children and young adults in Dubai · Overall

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 36 months

All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report, Crude

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro

Changes in intensity of pain (VAS 0 to 10) tested through tactile stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation · Medium term (24 hours to 2 months)

Dental caries · Children · Community/population-based (multiple countries), Study region: United States

Periodontal disease (periodontitis) coincidence · Patients with Crohn's disease (CD) and controls without IBD; adults, both sexes · Hospital/clinic-based case-control and cross-sectional studies in 11 countries; 15 studies total (1748 participants: 1104 Crohn's disease, 534 ulcerative colitis, 110 IBD-form unspecified); 5 studies pooled for this analysis, Crohn's disease (CD) vs healthy controls

Plasma level of hs-CRP (mg/L) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension · Long term, People diagnosed with periodontitis and other cardiovascular diseases except hypertension

Adverse events · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible;…

Subjective evaluation of the treatments by participants · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious…

Number of participants referred for surgical exposure of the PDC · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC) · 48 months (maximum; mITT)

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report

Mean dmft/DMFT · Arab children with special health care needs in Ras Al Khaimah · Overall

Amount of crowding (change in mandibular crowding) at 8 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth · 8 weeks

Endothelial function (flow-mediated dilation) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension · Short term, People diagnosed with periodontitis

Canine expansion (maxillary intercanine width) · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or…

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Case-control studies of children and adults (China, India, Czech Republic, Turkey), Dentition: Deciduous tooth decay

Hemoglobin (HGB) level · Preschool children (<6 years) · Overall

Mean DMFT (decayed, missing, filled permanent teeth) · Somalia

Oral health status (caries, calculus, gingivitis) · Children with beta-thalassemia major in the United Arab Emirates (Dubai) · Dubai, UAE

Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · In vivo (clinical); permanent posterior teeth, proximal surfaces, Dentin detection level

Change in systolic blood pressure (SBP, mmHg) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension · Short term (follow-up 2 months), People diagnosed with periodontitis and hypertension

Visible plaque prevalence · Schoolchildren aged 4-6 years in Dubai schools · Overall

Dental caries · Children · Community/population-based (multiple countries), Caries assessment: clinical and radiographic examination

Plasma level of hs-CRP (mg/L) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension · Long term, People diagnosed with periodontitis

Diagnostic accuracy for proximal caries detection (caries detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · In vivo (clinical); permanent posterior teeth, proximal surfaces, Caries detection level

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Dentin detection level

Outcome NR · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous…

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro

Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 36 months

All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report, Multivariable-adjusted

Specificity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Primary/mixed dentition

Oral hygiene knowledge and practices · Children and adolescents in the United Arab Emirates · UAE; schools/nurseries (Sharjah, Ajman; national survey)

Outcome NR · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance…

Dental caries · Children · Community/population-based (multiple countries), Sample size: 3,000 or fewer

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report, Crude

Survival rate of restorations (24 months) · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction) · 24 months, Primary molars (proximal atraumatic restorative treatment)

Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · In vivo (clinical); permanent posterior teeth, proximal surfaces, Dentin detection level

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report, Multivariable-adjusted

Diagnostic accuracy for proximal caries detection (caries detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · In vivo (clinical); permanent posterior teeth, proximal surfaces, Caries detection level

Dental caries prevalence · General Pakistani population (all ages and both sexes; predominantly children and adolescents) · Pakistan (school-, community-, and hospital/clinic-based cross-sectional surveys), Province: Sindh

Molar expansion (inter-molar distance) · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or… · Children (7 to 11 years)

Incidence of eruption of the PDC into the mouth · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC) · 24 months

Restoration failure rate · People with permanent or adult posterior teeth requiring restoration (parallel-group trials involved children aged 6… · Follow-up >= 3 years, Split-mouth trials

Changes in intensity of pain (VAS 0 to 10) tested through tactile stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation · Long term (more than 2 months)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro

Adverse events · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible;…

Diagnostic accuracy in previously restored teeth (secondary caries) · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Previously restored teeth (secondary caries)