Search review questions

Caries severity (mean DMFT) · 12-year-old children (permanent dentition) in Africa · Country: Sao Tome

Dental caries (later in life) · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western… · Later in life

Study-specific disease-state discrimination · Oral microbiome samples in 15 case-controlled studies

Molar caries detection accuracy · Dental images of human beings · Lee et al., 2018; CNN

Caries experience - % dft (descriptive), primary dentition · CL/P vs no CL/P; Table 4 (1 group/1 study)

Sensitivity for detecting enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies) · Analysis 2: network meta-analysis (all studies evaluating >=2 index tests)

Adverse events · 'Healthy' children with caries-free second primary molars, aged 3-5 years (schools and kindergartens, India and China)

Treatment failure (annual failure rate) · Children with severely decayed maxillary primary incisors treated by pulpectomy (non-vital pulp therapy) · 1 year, Reverse metal post (RMP) arm

Contribution to total daily fluoride intake · Adults · Poor fluoride in water (<0.3 mg/L)

Caries experience · European adolescents aged 16 years · Exact age

Clinical and radiographic success rate (>=6 months) · Human permanent teeth with symptomatic irreversible pulpitis due to carious pulp exposure · >=6 months, Symptomatic irreversible pulpitis

Dentinal caries in permanent (newly erupted) teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of… · 7-year follow-up, Enamel caries in primary dentition

Occlusal caries detection accuracy · Dental images of human beings · Casalegno et al., 2018; CNN

Early childhood caries (ECC) - association at lead SNP rs74470773 (3:33958083; nearest gene(s) PDCD6IP) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), rs74470773 (3:33958083); effect/non-effect allele T/C; MAF 0.47; direction across 5 cohorts -----

Occlusal caries detection accuracy · Dental images of human beings · Moutselos et al., 2019; MASK R-CNN; most common class

Caries prevalence · 12-year-old children (permanent dentition) in Africa · Setting: Urban

Restoration failure · Children with carious primary teeth · 4 years, ART; Class I

Dental caries experience · Children and adolescents (<18 years) living with HIV (CLWH)

Progression of non-cavitated enamel caries · Children with caries-free primary first molars (with or without caries on other teeth), aged 1-5 years (paediatric…

Difference in summary specificity (NMA, Analysis 2) · Fluorescence vs Visual

Persistent parotid enlargement prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

Dental caries (association with sugary drinks/sweets consumption) · Children (deciduous and/or permanent dentition) in low- and middle-income countries

Occlusal caries detection accuracy · Dental images of human beings · Moutselos et al., 2019; MASK R-CNN; center pixel class

Treatment failure (annual failure rate) · Children with carious primary molars treated by pulpotomy (vital pulp therapy) · 1 year, Preformed metal crown (PMC) arm

Progression of non-cavitated enamel caries · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department,…

Restoration failure · Children with carious primary teeth · 3 years, ART; Class II

Caries prevalence · 12-year-old children (permanent dentition) in Africa · Country: Malawi

Dental caries severity (median DMFT/dmft/DMFS/dmfs) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point)

Caries experience (mean DMFS) · European adolescents aged 12–19 years · Region: non-Scandinavian

Restorative index (RI = f/[d+f]) in the primary dentition · Children in the primary dentition with non-syndromic cleft lip and/or palate (CL/P) and comparable children without CL/P

Specificity for detecting enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies) · Analysis 1: fully within-person comparison (studies evaluating >=3 index tests)

Caries severity (mean DMFT) · 12-year-old children (permanent dentition) in Africa · Country: Malawi

Pulpal disease (signs/symptoms of pulp necrosis) · Children with dentine caries in primary and permanent teeth · 12 months, 3 studies (primary and permanent teeth)

Restoration success/failure · Children (5-7 years) with caries in primary teeth · 12 months

Treatment failure (annual failure rate) · Children with carious primary molars treated by pulpotomy (vital pulp therapy) · 1 year, Amalgam (A) arm

Difference in summary sensitivity (NMA, Analysis 2) · Transillumination vs Visual

Early childhood caries (ECC) - association with genetically predicted expression of CDH17 (chr8q22.1) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), CDH17 (chr8q22.1); 23 (5) tissues; significant (Bonferroni p < 3.09x10-6)

Food preference · Children and adolescents aged 0-19 years · Nonrandomized studies

Outcome NR · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance…

Oral problems prevalence · Pediatric leukemia patients in the United Arab Emirates · Overall

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · Caries detection level

Specificity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Non-histology reference standard (excavation, radiographs, separation)

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Mixed dentition caries

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies)

Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances · 1-24 months follow-up, Glass ionomer-based bonding agent

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · Dentin detection level

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Ethnicity: Asian

Dental caries (presence) · Individuals in Ethiopia assessed for dental caries

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · Caries detection level

Water samples with fluoride concentration below the acceptable range