Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

319 questions · 323 findings · 28 reviews · Eyes and Vision

No studies found 85 · 26.3%GRADE not reported 10 · 3.1%Very low 80 · 24.8%Low 103 · 31.9%Moderate 41 · 12.7%High 4 · 1.2%

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Change in foveation period durations of the waveform ‐ not reported · infantile nystagmus syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Quality of life at 6 months Assessed by 12‐Item Short Form Health Survey · older adults (aged 60 and over) with irreversible visual impairment

The intervention showed no clear difference in quality of life at 6 months Assessed by 12‐Item Short Form Health… (low certainty).

1 finding from 1 review

Intervention not reported

Corneal perforation or penetrating keratoplasty, or both, at 2 to 3 months · people with fungal ulcers

The intervention leads to lower corneal perforation or penetrating keratoplasty, or both, at 2 to 3… (high certainty).

1 finding from 1 review

Information video and counselling to improve access to cataract surgical services vs usual care

Service utilisation: uptake of referral · people with vision impairment caused by cataract

Information video and counselling to improve access to cataract… may leads to higher service utilisation: uptake of referral compared with standard care (low certainty).

1 finding from 1 review

Information video and counselling to improve access to cataract surgical services vs usual care

Service utilisation: uptake of surgery · people with vision impairment caused by cataract

Information video and counselling to improve access to cataract… may leads to higher service utilisation: uptake of surgery compared with standard care (low certainty).

1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants requiring further IOP‐lowering interventions (additional surgery, medications, or both) (lower number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

It is very uncertain whether phacoemulsification changes proportion of participants requiring further IOP‐lowering… compared with laser peripheral iridotomy (very low certainty).

1 finding from 1 review

Intervention not reported

Further surgical or laser interventions · adults with PACS or PAC, and previous PI

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Further surgical or laser interventions · adults with PAC or PACG, and previous PI
1 finding from 1 review

Oral antibiotics vs placebo

Economic costs and benefits of different interventions · adult participants with chronic blepharitis

The review found no eligible studies for this question.

1 finding from 1 review

Blue‐light filtering intraocular lenses (IOL) vs non blue‐light filtering IOL

Proportion of participants with adverse events with a probable causal link with the study interventions at six months · adults undergoing cataract surgery with IOL implantation

The review found no eligible studies for this question.

1 finding from 1 review