Cochrane · systematic review · CD015116

Lens extraction versus laser peripheral iridotomy for acute primary angle closure

Ong, AY, McCann, P, Perera, SA, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 42.9%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Phacoemulsification compared with laser peripheral iridotomy for acute primary angle closure

Population: Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure
7 questions
OutcomeEffectEvidenceStatus / GRADE
Proportion of participants with IOP control (higher number of events is better)
Phacoemulsification vs laser peripheral iridotomy
RR 1.66 [1.28, 2.15]2 studies · 97 participantsLow
Downgraded: risk of bias, inconsistency
Proportion of participants requiring further IOP‐lowering interventions (additional surgery, medications, or both) (lower number of events is better)
Phacoemulsification vs laser peripheral iridotomy
RR 0.07 [0.01, 0.51]2 studies · 99 participantsVery low
Downgraded: risk of bias, imprecision
Proportion of participants with 1 or more recurrent APAC episodes in the same eye (lower number of events is better)
Phacoemulsification vs laser peripheral iridotomy
RR 0.32 [0.01, 7.3]1 study · 37 participantsVery low
Downgraded: risk of bias, imprecision
Mean number of IOP‐lowering medications required (lower number of medications is better)
Phacoemulsification vs laser peripheral iridotomy
no estimate extracted1 study · 60 participantsLow
Downgraded: risk of bias, imprecision
Mean IOP, measured by any method (mmHg) (lower IOP is better)
Phacoemulsification vs laser peripheral iridotomy
no estimate extracted1 study · 62 participantsLow
Downgraded: risk of bias, imprecision
Mean change in angle findings, measured by any method
Phacoemulsification vs laser peripheral iridotomy
no estimate extracted2 studies · 94 participantsVery low
Downgraded: risk of bias, inconsistency
Adverse effects
Phacoemulsification vs laser peripheral iridotomy
no estimate extracted2 studies · 99 participantsLow
Downgraded: risk of bias, imprecision